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Re: Time scale of t4 and FAQ

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I have read your very detailed email, thanks for answering my questions. I will

have to read it twice to get my head round it lol.

I will look again on google scholar, many journals iv looked at are on animals,

with medical terminology with makes tough reading.

I'm sure to have more questions, but thanks for now. X

Jay

On 10 Jan 2011, at 02:38, ChuckB <gumboyaya@...> wrote:

>

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On 1/10/2011 4:44 PM, Jay wrote:

> I have read your very detailed email, thanks for answering my questions.

> I will have to read it twice to get my head round it lol.

>

> I will look again on google scholar, many journals iv looked at are on

> animals, with medical terminology with makes tough reading.

Be careful with the animal models. Although the hormones are the same in

mammals, the half lives are very different. One of the most egregious

mistakes of the UK endocrinology society is that they based explanations

for the superiority of T4 only medications on mouse half lives. They

claimed the half life for T3 was only 8 hours, when it was really 1-2 days.

My hypoT dog (now deceased, lymphoma) took 1,600 mcg of levothyroxine

each day. A healthy dog could get into your monthly T4 supply and suffer

no ill effects.

Chuck

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