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Also according to Hakala Research with their test results they

explained that, besides a symporter defect which you describe in

which iodine is absorbed but not taken into the cells and is just

excreted, there can be what they called an iodine organification

problem where iodine gets into the cell but does not attach to the

lipid complex for activation. Both of these situations, they seemed

to think were occuring though if one is not taking iodine supplements

yet still excretes a high % of iodine in the 24 hour urine iodine

test. Again I wish I had known about the 24 hour urine iodine spot

test before I had started taking iodine months ago. Wow...so much to

learn here. Thanks for your help Marlena. V

>

> Some reflections about loading tests: Dr Flechas is a bit more

> expensive for testing but you get a free consultation with each

test,

> and I have found them invaluable. I did a spot test with my first

> loading test, even after I began iodine supplementation and I'm very

> glad I did because it helped Dr. Flechas to see that I was very

> deficient even though my first loading results came back around

70%. My

> second loading results 3 months later, on 50mg of iodine/day were

only

> around 60%! He explained I had a common defect in iodine deficient

> states (and the owner of this site helped me to further

> understand this) - where because one has been deficient for awhile,

many

> of the receptors are shutdown and you excrete iodine even though you

> need it. After taking high doses for awhile the iodine receptors

begin

> to wake up again and you excrete less, until you start getting

> sufficient. Now after several more months I got up to around 80%

> excretion (90% is the goal). 

> Marlena

>

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Hmmm, good question . How do you know which is which? I saw the spot

test but had no clue what it is. Guess maybe that would b the palce to

begin, huh?

/MI

In other words if I am excreting 89.6% iodine, how do I know if I

have reached a good saturation level or if receptors are just shut

down and I am just excreting it? If my receptors are shut down, then

I would think I would not decrease iodine dosage, but if saturation

level is really reached I would decrease dosage somewhat. I hope I am

being clear on this questiion. LOL If I had known about the spot test

I would have done that several months ago before starting iodine. I

had been on 3 Iodoral (37 1/2mg) for several months when I just took

this iodine loading test with 89.6% iodine excreted. Thanks. V

>

> Some reflections about loading tests: Dr Flechas is a bit more

> expensive for testing but you get a free consultation with each

test,

> and I have found them invaluable. I did a spot test with my first

> loading test, even after I began iodine supplementation and I'm very

> glad I did because it helped Dr. Flechas to see that I was very

> deficient even though my first loading results came back around

70%. My

> second loading results 3 months later, on 50mg of iodine/day were

only

> around 60%! He explained I had a common defect in iodine deficient

> states (and the owner of this site helped me to further

> understand this) - where because one has been deficient for awhile,

many

> of the receptors are shutdown and you excrete iodine even though you

> need it. After taking high doses for awhile the iodine receptors

begin

> to wake up again and you excrete less, until you start getting

> sufficient. Now after several more months I got up to around 80%

> excretion (90% is the goal). 

> Marlena

>

------------------------------------

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Hi ,I think understand your concern and question. Since you were on 37.5 mg of iodine for several months before you took the loading test, I'm going to guess that your results were pretty accurate. However you won't know for sure until you do another loading test, which I would do 3 months from the time of the last test. If your excretion level goes down, then you will see that more receptors woke up to receive the iodine. However, like I said, I doubt this is the case, since you were on a pretty substantial dose for several months. That usually does the trick to wake them up. How are your bowels and the sweating? Is it better when you are on 25mg of Iodine as opposed to 37.5mg? Until your next test, I would go by your symptoms to guide your dosage.Hope this helps,Marlena> >> > Some reflections about loading tests: Dr Flechas is a bit more> > expensive for testing but you get a free consultation with each > test,> > and I have found them invaluable. I did a spot test with my first> > loading test, even after I began iodine supplementation and I'm very> > glad I did because it helped Dr. Flechas to see that I was very> > deficient even though my first loading results came back around > 70%. My> > second loading results 3 months later, on 50mg of iodine/day were > only> > around 60%! He explained I had a common defect in iodine deficient> > states (and the owner of this site helped me to further> > understand this) - where because one has been deficient for awhile, > many> > of the receptors are shutdown and you excrete iodine even though you> > need it. After taking high doses for awhile the iodine receptors > begin> > to wake up again and you excrete less, until you start getting> > sufficient. Now after several more months I got up to around 80%> > excretion (90% is the goal). > > Marlena> >>

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Hi ,

I had a high result also on the loading test, 83%. I had not yet

started supplementing. I think medical and lifestyle history plays a

part in deciding if the results of the test are " you are iodine

sufficient " or " your NIS has shut down because you are so deficient

and you need to flood your body with iodine to wake them up " . My

medical history included a low salt diet for 40 years, and a Mountain

Dew (bromide) daily for the same time frame. So Dr. Flechas felt that

I was in the second category. He has had me take 100 mg Iodoral for 6

weeks, then down to 50 mg for the remainder of 3 mos, at which time I

will retake the loading test.I can tell you I have had major detoxing

symptoms, so Dr. Flechas is right on with his evaluation of the results.

I hope my experience will lend a little light on your question.

Blessings-

Vicki

> >

> > Some reflections about loading tests: Dr Flechas is a bit more

> > expensive for testing but you get a free consultation with each

> test,

> > and I have found them invaluable. I did a spot test with my first

> > loading test, even after I began iodine supplementation and I'm very

> > glad I did because it helped Dr. Flechas to see that I was very

> > deficient even though my first loading results came back around

> 70%. My

> > second loading results 3 months later, on 50mg of iodine/day were

> only

> > around 60%! He explained I had a common defect in iodine deficient

> > states (and the owner of this site helped me to further

> > understand this) - where because one has been deficient for awhile,

> many

> > of the receptors are shutdown and you excrete iodine even though you

> > need it. After taking high doses for awhile the iodine receptors

> begin

> > to wake up again and you excrete less, until you start getting

> > sufficient. Now after several more months I got up to around 80%

> > excretion (90% is the goal). 

> > Marlena

> >

>

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Hi Marlena, my computer froze up so I don't know if my post flew or

not. If this is a duplicate I apologize. I was thinking along the

same lines as you. I just dropped down to 2 iodoral (25mg) today so

it is too soon to really tell if there are any symptom changes. I

will let you know if anything changes. I will take the test again in

3 months. Thanks so much for your help. V

>

> Hi ,I think understand your concern and question. Since you

were on

> 37.5 mg of iodine for several months before you took the loading

test,

> I'm going to guess that your results were pretty accurate. However

you

> won't know for sure until you do another loading test, which I

would do

> 3 months from the time of the last test. If your excretion level

goes

> down, then you will see that more receptors woke up to receive the

> iodine. However, like I said, I doubt this is the case, since you

were

> on a pretty substantial dose for several months. That usually does

the

> trick to wake them up. How are your bowels and the sweating? Is it

> better when you are on 25mg of Iodine as opposed to 37.5mg? Until

your

> next test, I would go by your symptoms to guide your dosage.Hope

this

> helps,Marlena

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  • 2 months later...

I waited to see if any newbies would answer this.

In the past people have said about 7 to 10 days.

Hoping you got your results now! :)

Let us know how uou did!

Respectfully,

Jeanetta Mastron CPhT BS

Pharm Tech Educator

F/O

>

> I was just curious how long it took to get your test results back. I

took it Nov. 11th and they

> told me I would know by Dec. 1st. Does it usually take that long??

>

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Thanks Jeanetta. Still haven't heard anything yet. Will keep you

posted.

> >

> > I was just curious how long it took to get your test results back. I

> took it Nov. 11th and they

> > told me I would know by Dec. 1st. Does it usually take that long??

> >

>

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  • 1 month later...

The interpretation depends upon

whether you are taking thyroid hormone replacement medication or not .

Your T4 is rather high if you are not on medication showing perhaps that you

are not converting this mainly inactive hormone to the active hormone T3, as

this is below the reference range. You need T3 to make every cell in your body

and brain function. Do you have reference range for the antibodies - and yes,

untreated hypothyroidism would leave you with a cold scalp and face, as well as

other parts of your body. Have you mentioned your facial pain to your GP?

Luv - Sheila

Hi all, I posted a few weeks ago, but have now got my

full test

results.Perhaps someone can interpret them for me.

TSH .08 (0.05 - 5.5)

T4 20.3 (10 -26)

T3 1.1 (1.3 - 2.6)

Antibodies 89iu/ml

Also, does anyone else here experience a cold scalp and face, and

facial pain? I have to wear a hat in bed and around the house!

Thanks, A

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Hi Sheila, sorry, I meant to say I'm on 125mcg of thyroxine.

Yes I've mentioned the facial pain to my gp on many occasions. He just

seems to shrug it off. It's really bad at the moment, and in fact my

left cheek looks quite puffy and feels doughy! It's almost impossible

to get an appointment at the moment, in fact they've started doing

'telephone consultations'! Great, eh?

The antibody ref range was 50, so at 89 it is raised.

Thanks again for you kind support,

-- In thyroid treatment , " Sheila " <sheila@...>

wrote:

>

> The interpretation depends upon whether you are taking thyroid hormone

> replacement medication or not . Your T4 is rather high if you

are not

> on medication showing perhaps that you are not converting this mainly

> inactive hormone to the active hormone T3, as this is below the

reference

> range. You need T3 to make every cell in your body and brain

function. Do

> you have reference range for the antibodies - and yes, untreated

> hypothyroidism would leave you with a cold scalp and face, as well

as other

> parts of your body. Have you mentioned your facial pain to your GP?

>

>

>

> Luv - Sheila

>

> Hi all, I posted a few weeks ago, but have now got my full test

> results.Perhaps someone can interpret them for me.

>

> TSH .08 (0.05 - 5.5)

> T4 20.3 (10 -26)

> T3 1.1 (1.3 - 2.6)

>

> Antibodies 89iu/ml

>

> Also, does anyone else here experience a cold scalp and face, and

> facial pain? I have to wear a hat in bed and around the house!

>

> Thanks, A

>

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Hi

Having

antibodies to your thyroid means that the antibodies see your thyroid as public

enemy number one and set about its gradual destruction, so you will need to be

on thyroid hormone replacement for life. Can you ask your GP to refer you to a

specialist to find out if your face pain is anything to do with being

hypothyroid or something else.?

Luv -

Sheila

Hi Sheila, sorry, I meant to say I'm on 125mcg of

thyroxine.

Yes I've mentioned the facial pain to my gp on many occasions. He just

seems to shrug it off. It's really bad at the moment, and in fact my

left cheek looks quite puffy and feels doughy! It's almost impossible

to get an appointment at the moment, in fact they've started doing

'telephone consultations'! Great, eh?

The antibody ref range was 50, so at 89 it is raised.

Thanks again for you kind support,

--

_,_._,___

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Hi A,

Classic inability to convert the inactive T4 into the

active T3 as T4 is much higher in it's range than the T3. As you have

antibodies then the autoimmune attacks will eventually destroy your

thyroid. Are you on thyroid meds? If so what.

All body systems are lowered with thyroid disease therefore odd

symptoms, especially a lowered body temp, are to be expected until you

are properly treated.

Subject: test results

Hi all, I posted a few weeks ago, but have now got my full test

results.Perhaps someone can interpret them for me.

TSH .08 (0.05 - 5.5)

T4 20.3 (10 -26)

T3 1.1 (1.3 - 2.6)

Antibodies 89iu/ml

Also, does anyone else here experience a cold scalp and face, and

facial pain? I have to wear a hat in bed and around the house!

Thanks, A

------------------------------------

TPA is not medically qualified. Consult with a qualified medical

practitioner before changing medication.

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Hi,

We get phone doc too, but it's far better than waiting for 2 weeks

for an appointment with your own doc- they do 'on the day' appts for

really urgent stuff, but you'll only see whose on duty. The problems of

living in a fast growing town.

Could the facial pain be sinusitis? - does it feel worse if you tilt

your face to look at your feet? If so antibiotics may well be the

answer. Us hypos seem to be very prone to ENT infections.

Subject: Re: test results

Hi Sheila, sorry, I meant to say I'm on 125mcg of thyroxine.

Yes I've mentioned the facial pain to my gp on many occasions. He just

seems to shrug it off. It's really bad at the moment, and in fact my

left cheek looks quite puffy and feels doughy! It's almost impossible

to get an appointment at the moment, in fact they've started doing

'telephone consultations'! Great, eh?

>

------------------------------------

TPA is not medically qualified. Consult with a qualified medical

practitioner before changing medication.

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  • 1 month later...

Hi Helen, no, your results are not

adequate. If you lived in the US or Germany, you would have been given a

diagnosis of hypothyroidism. The TSH ref. range in the US is 0.3 to 3.0 - and

in Germany, 0.3 to 2.5. Your Free T3 I cannot help with because we need the

reference range for each individual test result. Let us know what that is please.

Unless you build up your ferritin stores,

you will become anaemic. Your ferritin is terribly low - the usual reference

range for ferritin is between 20 and 200. Yours should be somewhere in the

region of 70 to 90. How much Ferrous Sulphate has your GP put you on and how

many times a day do you have to take it. Did he tell you that you should take

high doses of vitamin C (3/4000mgs) daily to stop you becoming constipated. Did

your GP tell you that it is absolutely vital you do NOT take your levothyroxine

anywhere near taking your iron supplement. You MUST take your thyroxine at

least 3 to 4 hours apart from your iron. Having low ferritin will stop your

thyroid hormone replacement from being absorbed - this is probably the reason

you feel so unwell. You should also ask for your B12, Vitamin D, magnesium,

copper and zinc to be tested.

Have a look at the Adrenal and Candida

Questionnaires in our files section of this forum web site and answer the

questions to see whether you might be suffering with low adrenal reserve or with

candida albicans. These too could stop your thyroid hormone from being

absorbed.

Luv - Sheila

Hi,I have got my test results and wonder what you

think of them,

TSH 3.91 ( was 2.16 in 08)

Free T4 14 (was 16 in 08)

Total T3 1.4.

There was a finding that my iron stores are partically low but not

anemic.Ferritin 5.

_,___

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Hi Sheila,

I have the results of the ranges for the free t3 is 0.9_2.4 nmol/L.I

hope this is what you mean.

I had the tests for b12 which was 504 ng/1 (200_1001).i also had the

blood test for copper but can2t find it on the results sheet.

Where do you get your information from as I was trying to find what

the ranges of ferrin I should have.

The docter said it was very low but never advised on taking the

supplements 3-4 hours after thryoxine.I have to take one 3 times a

day and a hour before having tea,coffee,wholegrains,milk and

eggs.Also a hour after having these.I wasn " t told about the vitamin c

to take.She just said to do this for 3 months then take another blood

test and go from there.she said it is probably to do with the diet

but I said I eat a lot of beef and cereals.I think it has been ever

since I had the girls as I was anemic just after having them and it

should have been checked regulary in the 3 years.

I am totally confused now and scared.

Thanks for your help if you didn " t tell me to go and get my ferrin

checked I wouldn2t have known still today.I feel totally sick that

you have to ask for results.

From Helen.

>

>

>

> Have a look at the Adrenal and Candida Questionnaires in our files

section

> of this forum web site and answer the questions to see whether you

might be

> suffering with low adrenal reserve or with candida albicans. These

too could

> stop your thyroid hormone from being absorbed.

>

>

>

> Luv - Sheila

>

> Hi,I have got my test results and wonder what you think of them,

> TSH 3.91 ( was 2.16 in 08)

> Free T4 14 (was 16 in 08)

> Total T3 1.4.

> There was a finding that my iron stores are partically low but not

> anemic.Ferritin 5.

>

> _,___

>

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Hi madhattercharliechurch (however

did you come to create such a name *grin*)

I am

so sorry to hear you have been going through so much - and damn and blast these

doctors who keep telling us we are depressed/hypochondriac/neurotic or

whatever. Anything that stops them investigating our condition further. You

don't mention whether you were started on levothyroxine. If you were, how much

are you taking and when was the last time you had an increase?

It is

always best in such a situation to sit down and write a letter to your doctor

and ask for the letter to be placed in your medical notes. List all of your

symptoms (have a look on our website www.tpa-uk.org.uk

and click on '#Hypothyroidism' and then click on 'Symptoms and Signs' and check

how many of these you have got. Also, take your basal temperature before you

get out of bed in a morning for at least 4 or 5 mornings and write down what

these are. Normal temperature is 98.6. If your temperature is 97.8 or less,

your metabolism is too low. List all the medications you are taking. Ask in the

letter to be referred to an endocrinologist (one who has his specialty is

thyroid disease rather then diabetes). Many sufferers of hypothyroidism have a

problem converting the mainly inactive thyroid hormone thyroxine (T4) to the

active thyroid hormone (T3). T3 is needed by every cell in your body and brain

to make them function. If you have a conversion problem, and a large minority

of suffers do, it could be that your muscles and joints are not getting T3. I

had this problem and my muscles were constantly going into severe spasm. Once it

was realised this was happening, I was started on Armour thyroid, a

medication that contains all the thyroid hormones and the pains have never come

back. I'm not saying this could be your problem, but you need to get your Free

T3 tested. If your local laboratory refuses to do the test, you can get this

done privately through Genova Diagnostics www.gdx.uk.net

..

In

your letter to your GP, ask to have the following blood tests done, Ferritin (stored

iron), B12, Vitamin D, Magnesium, zinc and copper. Also, when on the tpa web

site, click on 'Hypothyroidism' and then on 'Associated Conditions' and read

every thing there. These are all conditions that are associated with

hypothyroidism and if you suffer with any of them, each stop your thyroid hormone

from being absorbed.

Luv -

Sheila

..

The reason that the lab were so worried?

T4 = 0.5

TSH = >100

Latest results 11/12/08

T4 = 14.3

TSH = 2.

I am starting to feel cold again and my skin is reverting to the way

it was before. I don't know if this is as a result of the methotrexate

I have to take for the RA or is my thyroid not under control again?

Would my doctor take my symptoms seriously this time or would I be

accused of being a hypochondriac?

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Hi Val

Hypoxia and/or hypothyroidism cause magnesium to be dumped out of the cells and then be discarded by the kidneys. There isn't a magnesium 'conservation process' such as there is with sodium.

Magnesium and zinc are both 'divalent' and can substitute for each other in many enzyme functions.

Zinc and copper together form the basis ( activators of ) of the antioxidant SOD ~ which is SuperOxide Dismutase along with many other enzyme activating functions, and particularly in red cells (carbonic anhydrase) and mitochondria (the cytochromes ).

If either of these 'systems' go down, morbidity goes up and so does mortality.

Low zinc can be a marker for carcinogenesis, as can be low selenium.

Low magnesium may predispose to heart attacks with no signs of arteriosclerosis. So, the cholesterol testing to sell statins may prove exquisitely futile if the simple test for low magnesium is avoided on cost grounds alone.

yer pays yer money and yer takes yer choice ( or the doctor does, and you get no say in the matter ) bit like giving you a choice of hospital in which to be badly treated.

best wishes

Bob

>> Hi Sheila,> > What is the reason to add these blood tests? My endo just refused them, saying that he can not justify asking the GP for them.> > Val> > Magnesium, zinc and copper

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Thanks Bob,

If I see my Gp I will see if can persuade him.

Val

yer pays yer money and yer takes yer choice ( or the doctor does, andyou get no say in the matter ) bit like giving you a choice of hospitalin which to be badly treated.best wishesBob

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Hi Mad Hatter,

As you were not told of your diagnosis when you should

have been I think that a mere suggestion of medical malpractice will

have them falling over themselves to do your every wish. If not then

contact PALS.

-----Original

Subject: Test results

Hi allIt was only when I

broke down that he tested my reflexes and ordered a blood test. The

lab phoned him with the results as they were so worried and he phoned

me.

The reason that the lab were so worried?

T4 = 0.5

TSH = >100

Latest results 11/12/08

T4 = 14.3

TSH = 2.0

I am so angry that my symptoms were ignored and that I was dismissed

as a neurotic middle aged woman. The fact that I hardly ever go to the

doctors should have alerted them to the fact that I am not one to moan.

Why is it that we have to fight to be heard?

------------------------------------

TPA is not medically qualified. Consult with a qualified medical

practitioner before changing medication.

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For many sweating issues are adrenal related. Are you taking any form of adrenal support? With a bromide level like that staying constant my hunch is you aren't really that saturated. I would love to see you on 50 mgs or more but if you can't tolerate it then you will probably be detoxing like this at a slow rate for several years. I know someone who has been detoxing bromide for 5 years and has been on 50 or more mgs. If you are getting exposed to it somewhere you will have more issues with getting rid of it too.

Steph

Test Results

I receivead my iodine loading test results today. Previously in August 08, I had 89.6 iodine excreted, with 20.7mg Bromide Excreted. Being bromide excretion was high I remained on 25mg iodide daily, instead of 37.5mg I was on. The results I received today revealed 91% iodine excreted with 19.3 mg bromide excreted. I would have thought my bromide level would have gone down more than that. Should I just stay on 25mg iodoral and then retest again in 3-6 months?? If I take any more than 25mg iodoral I sweat terribly all day long. Thanks. V

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Hi Sheila,

I'm sorry that I have taken so long to reply. I had to go to hospital

yesterday for a steroid injection as I am having a major flare with

multiple joints involved. I never do things by half!

I am on 125mg of levothyroxine. I last had an increase last July I

think. I have fortnightly blood tests for liver and kidney function as

well as blood counts etc to ensure that the methotrexate isn't

effecting me negatively. I will ask for the additional bloodtests as

you have recommended.

I have asked friends to forward your letter to their MP's and I have

also send it to a member of the House of Lords. Let us hope that

something is done and soon.

Best wishes

x

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Yes I am taking adrenal support. In fact I just took another saliva

test...the results I haven't received as yet. I was sort of thinking

along the same lines as you, as that high saturation with the high

bromide excretion I'm having doesn't sound logical to me. I will

probably up to 37.5mgs Iodoral again and see how that goes. If I

start sweating again I might drop thyroid hormone 1/4 grain and see

what happens. I did read somewhere that if too much sweating occurs

with iodine, a decrease in thyroid hormone might help. My TSH does

run almost depressed anyway to avoid palpitations. Most doctors go

nuts with a TSH as low as what I have, but if it rises then I really

get thyroid symptoms. Luckly I have found a doctor that understands

this. I don't think I am being exposed to much bromide as I have

celiac disease and stay away from breads etc and most everything else

that I know of that has bromide in it. Thanks Steph for your

response. V

>

> For many sweating issues are adrenal related. Are you taking any

form of adrenal support? With a bromide level like that staying

constant my hunch is you aren't really that saturated. I would love

to see you on 50 mgs or more but if you can't tolerate it then you

will probably be detoxing like this at a slow rate for several

years. I know someone who has been detoxing bromide for 5 years and

has been on 50 or more mgs. If you are getting exposed to it

somewhere you will have more issues with getting rid of it too.

>

> Steph

>

> Test Results

>

>

> I receivead my iodine loading test results today. Previously in

August

> 08, I had 89.6 iodine excreted, with 20.7mg Bromide Excreted.

Being

> bromide excretion was high I remained on 25mg iodide daily,

instead of

> 37.5mg I was on. The results I received today revealed 91% iodine

> excreted with 19.3 mg bromide excreted. I would have thought my

bromide

> level would have gone down more than that. Should I just stay on

25mg

> iodoral and then retest again in 3-6 months?? If I take any more

than

> 25mg iodoral I sweat terribly all day long. Thanks. V

>

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It's worth a try and if you get too fatigued then up it again. It's always a balancing act.

Steph

Test Results> > > I receivead my iodine loading test results today. Previously in August > 08, I had 89.6 iodine excreted, with 20.7mg Bromide Excreted. Being > bromide excretion was high I remained on 25mg iodide daily, instead of > 37.5mg I was on. The results I received today revealed 91% iodine > excreted with 19.3 mg bromide excreted. I would have thought my bromide > level would have gone down more than that. Should I just stay on 25mg > iodoral and then retest again in 3-6 months?? If I take any more than > 25mg iodoral I sweat terribly all day long. Thanks. V>

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That's a

thought - how do we get hold of the House of Lords members names and addresses.

We should send it to each of them as we are dealing here with the Royal College

who have the Royal Charter - and they are above the government.

Luv -

Sheila

I have asked friends to forward your letter to their MP's and I have

also send it to a member of the House of Lords. Let us hope that

something is done and soon.

Best wishes

x

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No individual details but this might help?

http://www.parliament.uk/about/how/members/lords_contact.cfm

Luv Justeen

>

> That's a thought - how do we get hold of the House of Lords members

names

> and addresses. We should send it to each of them as we are dealing

here with

> the Royal College who have the Royal Charter - and they are above the

> government.

>

> Luv - Sheila

>

>

> I have asked friends to forward your letter to their MP's and I have

> also send it to a member of the House of Lords. Let us hope that

> something is done and soon.

> Best wishes

> x

>

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