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a.. The most common side effects of CellCept include: diarrhea, leukopenia (a

decrease in white blood cells), sepsis (an infection in the blood), vomiting and

a higher incidence of certain infections. People taking CellCept in combination

with other antirejection medications have a greater chance of developing

lymphomas and other cancers, especially skin cancer.

b.. If you are a woman of childbearing age, you must use 2 highly effective

methods of contraception 4 weeks prior to starting CellCept therapy and continue

contraception until 6 weeks after stopping CellCept treatment, unless abstinence

is the chosen method. If you are considering pregnancy, be sure to talk to your

doctor, as CellCept should not be used unless you cannot be successfully treated

with other immunosuppressant drugs.

c.. Cases of progressive multifocal leukoencephalopathy (PML), an infection of

the brain that is sometimes fatal, have been reported in patients treated with

CellCept. In reported cases, patients generally had risk factors for PML,

including treatment with immunosuppressant therapies. The most common symptoms

may include: clumsiness, progressive weakness, loss of movement or function in

one side of the body, and changes in vision, speech or personality.

d.. Severe neutropenia (a decrease in neutrophils, a type of white blood cell)

has been reported in up to 2% of kidney, 2.8% of heart and 3.6% of liver

transplant patients receiving CellCept at a dose of 3 grams daily.

e.. Gastrointestinal bleeding (requiring hospitalization) has been reported in

approximately 3% of kidney, 1.7% of heart and 5.4% of liver transplant patients

treated with CellCept at a dose of 3 grams daily.

Please be sure to talk to your doctor if you have any questions about your

condition or treatment.

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