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http://pbcers.org/whatis.htm The

Liver

The liver is the largest solid organ in the body, and is also the largest gland.

It weighs about three and a half pounds (1.6 kilograms). It measures about 8

inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down)

and is 4.5 inches (12 cm) thick. See what the liver does and how it can do so

much. PBC

As the PBC progresses, some patients require vitamin A, vitamin D,

vitamin E and vitamin K replacement therapy to add back fat-soluble vitamins

which are lost in fatty stools. A calcium supplement may be prescribed to help

prevent osteomalacia and osteoporosis.

When medical treatments, such as URSO 250 & URSO Forte, Actigall and

methotrexate, no longer control the disease, the patient should be evaluated for

a liver transplant. The end stage of PBC is liver failure. Many signs indicate

liver failure: increased bilirubin, jaundice, fluid accumulation or ascites,

malnutrition, gastrointestinal bleeding, intractable itching, bone fractures and

hepatic coma. Transplant is recommended before most of these symptoms occur.

Recent studies suggest that about 30% of those diagnosed with PBC will require a

transplant. The transplant outcome for PBC patients is excellent.

As with any other chronic illness, support and understanding is very

important in helping the PBC patient cope with day to day living.

Educate your Family Members and Friends about PBC. (Printable version)

ABC's of PBC by Tropple (PBCer)

Poem Me & My PBC by Janice Hurst (PBCer)

Anatomy & Functions of the Biliary System But you look good!

Common Characteristics of Liver Disease Complications of cirrhosis

Diagnostic tests Donating Blood

Fatigue in PBC Feeling Misunderstood: Living with Chronic Illness

" Fuzzy Brain " Some refer to it as a symptom in PBC Gastroenterology

Notebook

Glossary of Terms High Blood Pressure (Hypertension)

Hepatology terms all PBCers should know J. Worman, M.D. -

PBC

M. Vierling, M.D PBC site Liver, it's function & diseases

MedicineNet's Primary Biliary Cirrhosis (PBC) Center PBC is not

considered a terminal illness

Questions and Answers About Autoimmunity Sjogrens Syndrome

Strokes, Antiphospholipid Antibody Syndrome & PBC Waiting List

process & links of interest

Abbreviations - Find out what those Medical abbreviations mean

Antiphospholipid Syndrome - what is it and what YOU should know.

Article PBC Disease Stages Canadian Liver Foundation

Clinical Trials on PBC & other liver diseases Costochondritis and

PBC

Hepatic Encephalopathy Hepatology interesting PBC & related

research articles

Hepatology terms all PBCers should know Liver Biopsy WSEC

Liver Study Unit at the University of Chicago Hospitals Lupus with

Liver Involvement, Article by J. Wallace, M.D.

Mayo Clinic - PBC Medical dictionary & scientific medical

dictionaries

NORD - Primary Biliary Cirrhosis Osteoporosis & Other Bone Diseases

Osteoporosis & Liver Disease Osteoporosis Management ECO-DG

Dispatch: New Diagnostic Technique

PBC UK Conference Notes Primary Biliary Cirrhosis Canadian Liver

Foundation

Primary Biliary Cirrhosis (PBC) West Shore Endoscopy Center

Questions you may want to ask your doctor

Transplant links URSO dosage by weight and cost chart

US (800) 950-8085 and Canada (800) 565-3255

NOW A NOTE ON PBC TREATMENT

People with PBC NEED to take URSO 250 or URSO 500 or the generic version of

ursodiol acid.. Standard dosing is 1000 MG daily of URSO.or if ursodiol acid

(generic) 900 MH or 1200 MG. The generic comes in capsules of 300 MG whereas

URSO comes in doseage of 250 mMGor 500 MG. Your doctor will prescribe the

proper dose for you. This medication is PROVEN treatment for PBC and in many

cases PBCers have had improved liver panels and have not progressed. We have

PBCers here who have remained at stages 3 and 4 with no progression and they

will most likely never need to have a transplant. One of our new members as

of December, Anne, has been able to remain stable all because of taking her

URSO. Even though I have had my transplant (2004) I am still taking my urso

as having a transplant is not a cure. Although I have no sign of PBC at all I

gave been on urso since one month post TX ..taken as a preventive. I take the

generic and take 4 a day.equaling 1200 MG. Blessings, Joanne

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