Reducing Stomache Irritation from Arthritis Meds

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Current Question & Answer

Category: Arthritis | Topic: Arthritis medications and ulcers

http://www.mayohealth.org/mayo/askphys/qa001204.htm

Q. I have arthritis and regularly take an NSAID (Feldene). One of the

potential side effects of the drug is damage to the lining of the

stomach (ulcers) when used for an extended period. I always take the

medication with food but wonder if there would be a benefit to diluting

it in some way, say mixing it with food or liquid. By diluting the drug,

can I minimize the harmful effects on my stomach?

A. Opening the capsule and sprinkling the contents on your food isn't

likely to decrease your risk of gastrointestinal irritation and you may

not get the full dose of the medication. Feldene is the brand name for

piroxicam, a nonsteroidal anti-inflammatory drug (NSAID). A potential

side effect of all NSAIDs is gastrointestinal irritation, which can

cause abdominal pain, heartburn, nausea, change in bowel movements and

gastrointestinal ulcers and bleeding. Your risk of developing an ulcer

increases if you:

Have a personal history of ulcers

Are older than 60

Take corticosteroid medications, such as prednisone

Take other NSAIDs, such as ibuprofen or aspirin

Drink alcohol

Smoke

In addition, don't take NSAIDs if you take anticoagulant medications,

such as warfarin, because you may increase your risk of bleeding.

To reduce stomach irritation, take NSAIDs with a full glass of water or

milk. Never swallow an NSAID medication " dry " because it could stick in

your esophagus and cause irritation similar to a chemical burn. In

addition, try to eat something after taking an NSAID and remain seated

or upright rather than lying down.