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methotrexate question

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Hi:

Although Mickey has been on methotrexate for more than 3 years, and although

I'm sure I'd read all the info on the drug sheet before now, for some reason

I went searching again tonight, reading more. I found a web page that was

called " A Family Physicians Guide to Monitoring Methotrexate " . It was on the

website for the American Academy of Family Physicians.

On one part of it, it listed issues the doctor should go over with the

family when they make the decision to start using MTX. The last part of this

read " Warn patients about the potential development of malignancy,

specifically lymphoma. "

So of course I looked up lymphoma (even though I kind of knew it meant

cancer). I'm just a little confused. I do know that mtx is a cancer

treatment chemotherapy drug... in higher doses than is used for treating

arthritis, of course. But why would use of mtx seem to be listed as a risk

factor for DEVELOPING cancer when used as an arthritis drug? Does anyone

have any ideas about this? Am I just mis-interpreting?

the whole page can be found at

www.aafp.org/afp/20001001/1607.html

Feeling a little paranoid lately... seems like the more I read, the more I

find all of this is like a dog chasing its tail... nobody knows what causes

this, genetic predisposition, environmental triggers, bacterial

infections... and all these phrases keep popping up related to so many other

diseases, and all of them mention how much more prevalent it is than it used

to be. Am I the only one who worries about what pollution is doing to our

planet and our children? No, I know I'm not. Just overtired right now and

" awfulizing " . Not a good thing, and pointless to agonize over. I shouldn't

get started on wondering about why the chase for the almighty profit line

and dividend payouts should blind corporations to the fact that so far, no

one has found another habitable planet - do those people not have children

or grandchildren? If they're smart enough to run multinational corporations,

can they not see what is happening to us, our planet, our children, because

of pollution? Okay, I'm getting off my soapbox now...

Lynn

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