Guest guest Posted December 24, 2003 Report Share Posted December 24, 2003 When Baron Clemens Von Pirquet coined " allergen " from " allos " -altered or other, and " ergon " for action, " allergy " was meant to express the concept of a reaction that was out of the normal range of human response. An extraordinary response that calls attention to itself by being different from most folks. So allergy became sort of a blanket term that didn't really become applied to the different abnormal responses, I guess it got applied to mast cell degranulation and IgE responses by default. There's IgG response and who knows how many others waiting to be discovered? Jens Ponikau's Eosiniphilic response to inhaled fungal toxins is a systemic response rather than the sneezy, watery eye response that most people connect with " allergy " . So you go to an allegist for the runny nose, but see an immunologist for the IgG systemic response. The interesting thing about responses to neurotoxins is that they actually outstrip the speed of the blood to the brain. This is a true neurological response channeled to the brain through olfactory nerve stimulation. Certain scents are well known to have this direct neural stimulation. So now you gots to go see the neurologist. I suspect that we're simulataneously dealing with components of at least three different types of responses that all come under the heading of " allergy " that still remain to be subclassified in a meaningful way. I would be amazed if we weren't having an allergic response to inhaled antigens PLUS a systemic " eosinophilic " response AND a neurological " limbic kindling " response to those nasty neurotoxins. Wouldn't it be great to find one kind of doctor who knows about all the different " allergic " responses rather than having to see three? Doesn't it feel like mold is a " triple Whammy " ? - Quote Link to comment Share on other sites More sharing options...
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