Seizures, keto diet side effects, homocysteine, labs, links--Joey

[Guest guest]

Hi ,

Let's hope the light therapy helps Mallorie. I tried it once, and

had a bad experience, but that doesn't mean it won't work for others.

Some other information turned up that you may find useful. In

experiments, homocysteine is used to cause seizures. Anticonvulsants

can reduce levels of folic acid and B6, which will raise the level of

homocysteine. The ketogenic diet may cause some nutrient

deficiencies which can raise homocysteine levels.

Could this be a factor in why Mallorie is not yet responding well

to it? From what you wrote about her behavior, it sounds like she is

hurting in some way. Was Mallorie tested before or since starting

the diet for homocysteine levels? I found very little about

homocysteine and the ketogenic diet when searching on the web. The

article on anticonvulsants gives some good background on

anticonvulsants and vitamin interactions. Also, within the article

are links to homocysteine, methionine, and other related nutritional

issues. Below are links to labs also. Some of the other articles may

give you some ideas on what to look for now.

Zoe

These are the three laboratories I know of who do some testing for

metabolic disorders, though have no experience with them.

Health Research Institute - Pfeiffer Treatment Center

Health Research Institute andPfeiffer Treatment Center are leaders in

the research and treatment of biochemical imbalances. Our Mission ...

www.hriptc.org/

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Great Smokies Diagnostic Laboratory : Leaders in Functional ...

Great Smokies Diagnostic Laboratory (GSDL) has been providing

physicians worldwide with innovative, quality assessments of

physiological function for more ...

www.gsdl.com/

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The Great Plains Laboratory

About the Director of The Great Plains Laboratory. Dr. Shaw

received a Ph.D. in biochemistry and human physiology from the ...

www.autism.com/shaw-yeast/contents.html

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The Ketogenic Diet

.... The classic ketogenic diet is insufficient in several vitamins

and minerals:

B complex, vitamins C and D, folate, iron, calcium, magnesium, and

zinc. ...

www.medscape.com/viewarticle/417997_8

http://www.gnc.com/health_notes/Drug/Anticonvulsants.htm

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LE Magazine, December 2000 - Report: Vitamin B12: Surprising New ...

.... B12 is in the news because it lowers homocysteine and protects

against atherosclerosis.

It's also vital for maintaining methylation reactions that repair

DNA ...

www.lef.org/magazine/mag2000/dec2000_report_b12_1.html

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Just basic information

Facts About Vitamin B6

.... Acute isoniazid toxicity can result in coma and seizures ... What

is the relationship

between vitamin B6, homocysteine ... of vitamin B6, folic acid, or

vitamin B12 may ...

Description: Includes functions, good food sources, suggested intake,

and deficiency signs about the vitamin known...

Category: Health > Nutrition > Nutrients in Foods > Vitamins and

Minerals > Pyridoxine

www.cc.nih.gov/ccc/supplements/vitb6.html

The Ketogenic Diet

.... The classic ketogenic diet is insufficient in several vitamins

and minerals:

B complex, vitamins C and D, folate, iron, calcium, magnesium, and

zinc. ...

www.medscape.com/viewarticle/417997_8

Calcif Tissue Int 1979 Aug 24;28(1):17-22 Links

Disordered mineral metabolism produced by ketogenic diet therapy.

Hahn TJ, Halstead LR, DeVivo DC.

Vitamin D and mineral metabolism status was examined in five children

maintained chronically on combined ketogenic diet-anticonvulsant drug

therapy (KG), and the results compared to those obtained in 18

patients treated with anticonvulsant drugs alone (AD) and 15 normal

controls. KG patients exhibited biochemical findings of vitamin D

deficiency osteomalacia: decreased serum 25-hydroxyvitamin D (25OHD)

and calcium concentrations, elevated serum alkaline phosphatase and

parathyroid hormone concentrations, decreased urinary calcium and

increased urinary hydroxyproline excretion, and decreased bone mass.

Although the KG and AD groups demonstrated similar reductions in

serum 25OHD concentration, the KG patients exhibited a significantly

greater reduction in bone mass. In response to vitamin D

supplementation (5000 IU/day), mean bone mass in the KG group

increased by 8.1 +/- 0.9% (P less than 0.001) over a 12-month period.

These results suggest that ketogenic diet and anticonvulsant drug

therapy have additive deleterious effects on bone mass and that these

effects are partially reversible by vitamin D treatment.

PMID: 115548 [PubMed - indexed for MEDLINE]