Guest guest Posted March 7, 2003 Report Share Posted March 7, 2003 Total and cause specific mortality among Swedish women with cosmetic breast implants: prospective study V C M Koot, clinician a, P H M Peeters, associate professor a, F Granath, associate professor b, D E Grobbee, professor a, O Nyren, professor b. a Julius Centre for Health Sciences and Primary Care, University Medical Centre, Box 85500, 3508 GA Utrecht, Netherlands, b Department of Medical Epidemiology, Karolinska Institute, Box 281, S-171 77 Stockholm, Sweden Correspondence to: V C M Kuck-Koot, Comprehensive Cancer Centre Middle Netherlands, PO Box 19079, 3501 DB Utrecht, Netherlands kuckkoot@... The potential health hazards of breast implants have been heavily debated for the past decade, yet only one study has reported on long term mortality among women with such implants, and around one fifth of the participants were lost to follow up. 1 2 We assessed total and cause specific mortality among Swedish women who underwent augmentation mammoplasty between 1965 and 1993. As a desire for cosmetic surgery represents underlying psychopathology in some patients, we hypothesised that deaths due to suicide may be over-represented.3 Subjects and methods Top Subjects and methods Results Comment References Details about accrual of the cohort have been given elsewhere.4 We obtained records from the Swedish Inpatient Register of all 15-69 year old women who had had breast implants (n=7585) in 1965-93. We identified records with erroneous registration numbers or where emigration or death occurred before surgery through linkages with registers held by Statistics Sweden, using the unique national registration numbers. We excluded such records and records where surgery occurred at hospitals without surgical services (n=138). We also excluded women who had received an implant after surgery for breast cancer (n=3926), identified through the cancer register. The final study cohort comprised 3521 women, with a mean age of 31.6 (SD 8.6) years. Follow up started on the day of first implantation surgery and stopped at date of emigration, death, or end of follow up (31 December 1994), whichever occurred first. The cohort members were followed for an average of 11.3 (range 0.3-29.9) years, corresponding to 39 735 person years at risk. We compared the observed number of deaths with the expected number of deaths, the ratio of these two numbers giving the standardised mortality ratio. We obtained the expected number of deaths by multiplying the observed number of person years at risk in the cohort, divided into 5 year age strata and 1 calendar year strata, by the stratum specific mortality rates, derived from official Swedish death statistics. The standardised mortality ratio can therefore be viewed as a measure of relative risk, with the Swedish female population matched for age and calendar year serving as reference. We calculated 95% confidence intervals, assuming that the number of observed events followed a Poisson distribution. We coded underlying causes of death according to the international classification of diseases (7th, 8th, and 9th revisions) into suicide, unintentional injury, cardiovascular diseases, malignancies, and other causes. Results Top Subjects and methods Results Comment References Although 58.7 deaths were expected, 85 women died (standardised mortality ratio 1.5, 1.2 to 1.8; table). Fifteen women committed suicide, compared with 5.2 expected deaths (2.9, 1.6 to 4.8). Excess deaths were also due to malignant disease (1.4, 1.0 to 1.9), mainly lung cancer. The number of deaths for all other causes was close to expected. View this table: [in this window][in a new window] Standardised mortality ratios for total and cause specific mortality in 3521 Swedish women with cosmetic breast implants Comment Top Subjects and methods Results Comment References Women who undergo cosmetic surgery for breast augmentation are more likely to commit suicide than women from the general population. The 50% excess mortality found by us in our prospective study of 3000 Swedish women contrasts with the decreased mortality reported from the United States.2 This may reflect different reasons for self selection for plastic surgery or may be an effect of losses to follow up in the American study. Both the American study and our study did, however, show an increased risk for suicide in women opting for breast augmentation. Our excess mortality was explained by the excess of suicides and deaths from malignant disease. Deaths due to malignancy were mainly linked to smoking, previously shown as common in our cohort.5 Given the well documented link between psychiatric disorders and a desire for cosmetic surgery, the increased risk for death from suicide may reflect a greater prevalence of psychopathology rather than a causal association between implant surgery and suicide.3 Surgeons evaluating candidates for breast implant surgery need to be vigilant for subtle signs of psychiatric problems. Acknowledgments Contributors: VCMK, the principal investigator, discussed the core ideas, performed the record linkages, outlined and performed analyses, and wrote most of the paper. PHMP discussed the core ideas and participated in data interpretation and writing of the paper. FG participated in discussions about the core ideas, made suggestions about analyses, and helped VCMK with the practical analysis. DEG discussed the core ideas, the design of the study, the interpretation of the data, and writing of the paper. ON initiated the research, discussed the core ideas, formulated the primary study hypothesis, made suggestions about analyses and interpretation of the data, and supervised the writing. DEG and ON will act as guarantors for the paper. Footnotes Funding: This work was supported by a contract from the International Epidemiology Institute, Rockville, MA. VCMK was financially supported by the Netherlands Organization for Scientific Research. Competing interests: None declared. References Top Subjects and methods Results Comment References 1. Angell M. Evaluating the health risks of breast implants: the interplay of medical science, the law, and public opinion. N Engl J Med 1996; 334: 1513-1518[Free Full Text]. 2. Brinton LA, Lubin JH, Burich MC, Colton T, Hoover RN. Mortality among augmentation mammoplasty patients. Epidemiology 2001; 12: 321-326[CrossRef][iSI][Medline]. 3. Hasan JS. Psychological issues in cosmetic surgery: a functional overview. Ann Plast Surg 2000; 44: 89-96[iSI][Medline]. 4. Nyren O, Yin L, fsson S, McLaughlin JK, Blot WJ, Engqvist M, et al. Risk of connective tissue disease and related disorders among women with breast implants: a nation-wide retrospective cohort study in Sweden. BMJ 1998; 316: 417-422[Abstract/Free Full Text]. 5. Fryzek JP, Weiderpass E, Signorello LB, Hakelius L, Lipworth L, Blot WJ, et al. Characteristics of women with cosmetic breast augmentation surgery compared with breast reduction surgery patients and women in the general population of Sweden. Ann Plast Surg 2000; 45: 349-356[iSI][Medline]. (Accepted 17 January 2003) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2003 Report Share Posted December 14, 2003 In a message dated 12/14/03 2:42:30 PM Eastern Standard Time, heidis@... writes: > Oh, I agree and certainly I don't think YOU are (though > if it was meant in a joking sense it could be humorous). > I don't think those kinds of " activities " are the sole > domain of men either ... I've just never met a woman > who would *pay* to see a man naked (though we > do seem to pay for " romance novels " a lot). Well, there are Chip 'n Dales clubs, etc. I think the main difference seems to me that male strip clubs are more tasteful, whereas strip clubs with women for men can be either classy or downright nasty. I've never been to either. Chris Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2003 Report Share Posted December 14, 2003 >I'm sure no one on this list is biting for >Titties, and clearly the sex of the moderator has no relation to their ability or >motivation to keep out spam. > >Chris Oh, I agree and certainly I don't think YOU are (though if it was meant in a joking sense it could be humorous). I don't think those kinds of " activities " are the sole domain of men either ... I've just never met a woman who would *pay* to see a man naked (though we do seem to pay for " romance novels " a lot). -- Heidi Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2003 Report Share Posted December 14, 2003 CLEVER > > > > Well, there are Chip 'n Dales clubs, etc. > > I think you probably meant " Chippendales " clubs > unless you're actually talking about strippers for lady > chipmunks. In which case I'm sure the " girls " are far > more interested in the dancers' nuts than anything else. > Although I'm sure such a club would be a good place to > go if you're just looking for a little tail. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2003 Report Share Posted December 15, 2003 >> >> Well, there are Chip 'n Dales clubs, etc. > >I think you probably meant " Chippendales " clubs >unless you're actually talking about strippers for lady >chipmunks. In which case I'm sure the " girls " are far >more interested in the dancers' nuts than anything else. >Although I'm sure such a club would be a good place to >go if you're just looking for a little tail. > > My impression from being to such events is that the girls go there to " be rowdy " -- scream and be rude and unladylike -- with their girlfriends. It is a social event ... but the guys really are NOT the focus. I mean, it is fun to reverse the normal social order and scream at a guy, but most ladies would NOT be interested if they guy actually came to the table. I think the whole issue is best summarized in the following joke: A studly man comes into a bar and sidles up next to a woman. He says to her " I will do anything for $25, that you can write in 3 words " . " Anything??? " she asks, her eyes widening. " Anything " . says the stud. The woman looks into her handbag, finds $25 and a piece of paper. She thinks, then writes 3 words on the paper and hands it to the stud with the $25. He opens the paper ... and it says ... .... .... .... .... -- " Clean my house " . -- Heidi Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2003 Report Share Posted December 15, 2003 > Friday did a lot in the seventies to show that women have sexual fantasies and appetites too (as shown in her 3 volumes of collected women's fantasies). We're finally breaking out of that " good girls don't " crap. > >Filippa True, and really I wasn't trying to imply that. As far as marketing spam goes, very, very little is targeted at women. Probably because most women aren't really that much in the market for looking at naked men, to the point that it makes spamming them worthwhile. Considering the amount of spam I get that is targeted at MEN, I find the discrepency kind of humorous. Also, the mags that are theoretically " porn for women " really are a lot different than the equivalents for guys. Friday's books, and Anne Rice's, for instance, actually have PLOTS! -- Heidi Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2003 Report Share Posted December 15, 2003 In a message dated 12/15/03 6:47:48 PM Eastern Standard Time, heidis@... writes: > > Friday's books, and Anne Rice's, for instance, > actually have PLOTS! Playboy has articles. Chris Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2003 Report Share Posted December 15, 2003 > > My impression from being to such events is that the girls > go there to " be rowdy " -- scream and be rude and unladylike -- > with their girlfriends. It is a social event ... but the > guys really are NOT the focus. I mean, it is fun to reverse > the normal social order and scream at a guy, but most ladies > would NOT be interested if they guy actually came to the table. It was just a joke. I meant the lady chipmunks were interested in the dancers pecans, walnuts, etc. and chipmunks are distinguished from other squirrels, by among other things, having a " little tail " . Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2003 Report Share Posted December 15, 2003 Heidi wrote " -- " Clean my house " . -- Heidi, that was hilarious!!! Sheryl Sheryl Illustrations http://dovedesignsrus.com Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2003 Report Share Posted December 15, 2003 >It was just a joke. I meant the lady chipmunks were >interested in the dancers pecans, walnuts, etc. and >chipmunks are distinguished from other squirrels, by >among other things, having a " little tail " . > > Ooooh .... now I get it. Arrgh. Jokes like that will drive me " nuts " . -- Heidi Quote Link to comment Share on other sites More sharing options...
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