Fw: Subject Reference: Severe migratory granulomatous reactions to silicone gel in

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Martha Murdock, DirectorNational Silicone Implant Foundation | Dallas Headquarters"Supporting Survivors of Medical Implant Devices"4416 Willow LaneDallas, TX 75244-7537

----- Original Message ----- From: gigi*

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Sent: Saturday, April 05, 2003 12:02 AM

Subject: Subject Reference: Severe migratory granulomatous reactions to silicone gel in

: Teuber SS, et al. Severe migratory granulomatou..UI - 99188572PMID- 10090186DA - 19990507DCOM- 19990507LR - 20001218IS - 0315-162XVI - 26IP - 3DP - 1999 MarTI - Severe migratory granulomatous reactions to silicone gel in 3 patients.PG - 699-704AB - In humans implanted with silicone gel breast prostheses, a mild foreignbody response results in the formation of a collagenous capsule around the prosthesis. Although many such patients may show evidence of a microscopic granulomatous foreign body reaction upon examination of capsular materialat explantation of a prosthesis, it is unusual to have large, palpable granulomas, even in the presence of rupture or leakage. Rare patients have had severe local inflammation and complications resulting from silicone migration to the axilla, arm, or abdominal wall. We describe 3 patients who had deforming granulomas after implant rupture, along with other consequences of silicone gel migrating down the upper extremity. Silicone gel, once it leaves the implant, is not biologically inert and in somepersons can elicit profound pathologic responses.AD - Veterans Affairs Northern California Health Care System, Pleasant Hill,USA. steuber@... - Teuber, S SAU - Teuber SSFAU - Reilly, D AAU - Reilly DAFAU - Howell, LAU - Howell LFAU - Oide, CAU - Oide CFAU - Gershwin, M EAU - Gershwin MELA - engPT - Journal ArticleCY - CANADATA - J RheumatolJID - 7501984RN - 0 (Silicone Gels)SB - IMMH - AdultMH - Arm/pathologyMH - Breast/pathologyMH - Breast Implantation/*adverse effectsMH - Breast Implants/*adverse effectsMH - Case ReportMH - FemaleMH - Foreign-Body Migration/diagnosis/*etiologyMH - Granuloma, Foreign-Body/diagnosis/*etiologyMH - HumanMH - Magnetic Resonance ImagingMH - Middle AgeMH - *Prosthesis FailureMH - Silicone Gels/*adverse effectsMH - Skin/pathologyEDAT- 1999/03/25MHDA- 1999/03/25 00:01PST - ppublishSO - J Rheumatol 1999 Mar;26(3):699-704. Show:

gigi for your personal use only, it will be placed on my web site, and the, Canadian Connection. I will pass it on to our, Ruby Rhan, and Tony 'Tiger'

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