Guest guest Posted June 19, 2003 Report Share Posted June 19, 2003 > Semin Arthritis Rheum 1994 Aug;24(1 Suppl 1):11-7 > > > Silicone toxicology. > > Busch H > > Baylor College of Medicine, Houston, TX 77030. > > Silicone, a man-made polymer containing the element silicon, has been used > in a variety of medical devices including breast implants. Silicone was > used, in part, because it was suggested to have the property of biological > inertness. Inert materials do not affect chemical, physiological, or > immunological processes. Silicone is not inert. Silicone from breast > implants "bleeds" through the surrounding envelope and is present in the > surrounding capsule or migrates to other distant locations. Silicone and/or > the multiple chemical contaminants elicit foreign body reactions associated > with granulomatous inflammation and fibrosis. Silicone and its contaminants > have the potential for significant toxicity in the implant recipient. > > Publication Types: > Review > Review, tutorial > > PMID: 7801134, UI: 95099335 > Quote Link to comment Share on other sites More sharing options...
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