MTX may repair bone erosions

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CASE REPORT

A case of juvenile idiopathic arthritis exhibiting repair of systemic bone

erosion in response to continuation of MTX therapy after achievement of

clinical remission

http://www.springerlink.com/content/f54431042h672v00/

MODERN RHEUMATOLOGY DOI: 10.1007/s10165-011-0424-9

Abstract

We report a patient with rheumatoid factor-positive polyarthritis-type

juvenile idiopathic arthritis (JIA) in whom clinical remission was achieved

within 10 months after the start of methotrexate (MTX) therapy, and systemic

repair of bone erosion was noted 8 months after clinical remission.

These results indicate that even in cases of active JIA with the development

of bone erosion, continuation of MTX therapy after the achievement of

clinical remission can improve the prognosis, including repair of bone

destruction.

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