Treatment of acute hepatitis C with interferon alfa-2b

[Guest guest]

Hi Suzy,

The population of Portland proper is about 531,000 at last count. The

greater Portland metro area is about 1.8 million.

Bob

Re: Treatment of Acute Hepatitis C with

Interferon Alfa-2b

> Bob,

> I truly loved Portland! It was a wonderful city, the people were very

> friendly and the country as I said is just beautiful. I think I could

live

> there very easily. My children are thinking of moving out there so I will

> most likely be visiting many more times if they do. am really looking

> forward to it, there were so many things we did not get to see. How big is

> it? there was debate on that subject so you would have the most accurate #

> Thanks

> Suzy

>

>

>

>

> _________________________________________________________________

> Get your FREE download of MSN Explorer at http://explorer.msn.com/intl.asp

>

>

>

>

[Guest guest]

OK sorry folks, i shouldn't have aske d the population of a city. I

apologize, it did help taking a vacation though, gave me a rest and then

came back and found out I had relapsed so might be the best vacation I wil

have for awhile because I anticipate all the symptoms returning soon. ( the

ones I had before starting treatment) Sorry if I caused anyone any trouble.

Suzy

_________________________________________________________________

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[Guest guest]

OK sorry folks, i shouldn't have aske d the population of a city. I

apologize, it did help taking a vacation though, gave me a rest and then

came back and found out I had relapsed so might be the best vacation I wil

have for awhile because I anticipate all the symptoms returning soon. ( the

ones I had before starting treatment) Sorry if I caused anyone any trouble.

Suzy

_________________________________________________________________

Get your FREE download of MSN Explorer at http://explorer.msn.com/intl.asp

[Guest guest]

Sylv,

Thank you for the cheery note and the optimism, that is good to know, I

still tink at this point I am going to wait. will decide on down the road

if symptoms start gettting worse again, can feel them a little but no t as

much as before so will hang in ther ty for hugs

_________________________________________________________________

Get your FREE download of MSN Explorer at http://explorer.msn.com/intl.asp

[Guest guest]

Sylv,

Thank you for the cheery note and the optimism, that is good to know, I

still tink at this point I am going to wait. will decide on down the road

if symptoms start gettting worse again, can feel them a little but no t as

much as before so will hang in ther ty for hugs

_________________________________________________________________

Get your FREE download of MSN Explorer at http://explorer.msn.com/intl.asp

[Guest guest]

Hi Suzy,

I think it was okay to share your experiences here..I might even take my next

vacation to Portland!

Dr Sharat C Misra

Re: Treatment of Acute Hepatitis C with

Interferon Alfa-2b

OK sorry folks, i shouldn't have aske d the population of a city. I

apologize, it did help taking a vacation though, gave me a rest and then

came back and found out I had relapsed so might be the best vacation I wil

have for awhile because I anticipate all the symptoms returning soon. ( the

ones I had before starting treatment) Sorry if I caused anyone any trouble.

Suzy

_________________________________________________________________

Get your FREE download of MSN Explorer at http://explorer.msn.com/intl.asp

[Guest guest]

Hi Suzy,

I think it was okay to share your experiences here..I might even take my next

vacation to Portland!

Dr Sharat C Misra

Re: Treatment of Acute Hepatitis C with

Interferon Alfa-2b

OK sorry folks, i shouldn't have aske d the population of a city. I

apologize, it did help taking a vacation though, gave me a rest and then

came back and found out I had relapsed so might be the best vacation I wil

have for awhile because I anticipate all the symptoms returning soon. ( the

ones I had before starting treatment) Sorry if I caused anyone any trouble.

Suzy

_________________________________________________________________

Get your FREE download of MSN Explorer at http://explorer.msn.com/intl.asp

[Guest guest]

OK OK I'm really getting tired of reading these news articles where

they say CURE!

The articles in particular are the ones from a recent German study

done on ACUTE hep c cases.

The journalist says " cure " . How can they say that?

Remission, possibly, but these people haven't been without a viral

load long enough to say cure.

Just gripes my butt haha

alley

[Guest guest]

OK OK I'm really getting tired of reading these news articles where

they say CURE!

The articles in particular are the ones from a recent German study

done on ACUTE hep c cases.

The journalist says " cure " . How can they say that?

Remission, possibly, but these people haven't been without a viral

load long enough to say cure.

Just gripes my butt haha

alley

[Guest guest]

N Engl J Med 2001 Nov 15;345(20):1452-7

Treatment of acute hepatitis C with interferon alfa-2b.

Jaeckel E, Cornberg M, Wedemeyer H, Santantonio T, Mayer J, Zankel M,

Pastore G, Dietrich M, Trautwein C, Manns MP

Medizinische Hochschule Hannover, Germany.

BACKGROUND: In people who are infected with the hepatitis C virus (HCV)

chronic infection often develops and is difficult to eradicate. We sought to

determine whether treatment during the acute phase could prevent the

development of chronic infection. METHODS: Between 1998 and 2001, we

identified 44 patients throughout Germany who had acute hepatitis C.

Patients received 5 million U of interferon alfa-2b subcutaneously daily for

4 weeks and then three times per week for another 20 weeks. Serum HCV RNA

levels were measured before and during therapy and 24 weeks after the end of

therapy. RESULTS: The mean age of the 44 patients was 36 years; 25 were

women. Nine became infected with HCV through intravenous drug use, 14

through a needle-stick injury, 7 through medical procedures, and 10 through

sexual contact; the mode of infection could not be determined in 4. The

average time from infection to the first signs or symptoms of hepatitis was

54 days, and the average time from infection until the start of therapy was

89 days. At the end of both therapy and follow-up, 43 patients (98 percent)

had undetectable levels of HCV RNA in serum and normal serum alanine

aminotransferase levels. Levels of HCV RNA became undetectable after an

average of 3.2 weeks of treatment. Therapy was well tolerated in all but one

patient, who stopped therapy after 12 weeks because of side effects.

CONCLUSIONS: Treatment of acute hepatitis C with interferon alfa-2b prevents

chronic infection.

Publication Types:

a.. Clinical trial

b.. Multicenter study

PMID: 11794193, UI: 21544504