Vioxx

[Guest guest]

did they cause the ulcers?

Re: Viox

>has anyone tryed vioxx?

>

[Guest guest]

Hi,

I've been taking Celebrex. Just be careful if you

have a sensitive stomach. They can make it get upset.

The docs, and PT were always asking me if I was taking

my anti-inflamitories. I'm like occasionaly, however

it makes my GERD (acid reflux) act up.

No sleep because of GERD, or because my knees, hip hurt?

So, I compromise. When I had a really rough workout, or

walk for a long while. I give in an take one. However I try not

to take them everyday. I did at the oneset back in feb.

However had my GERD come back horribly. I was trying

to figure out what I changed in my diet to make it

flare up, nothing. It was the celebrex.

Good luck, just be careful and pay attention

to any stomach issues.

Connie

[Guest guest]

It seem alot of Ortho docs are old school and any NSAID in their

minds thin the blood. Better safe than sorry. But they are not the

ones in pain! So when the ortho's PA told me to stop, I said no. My

Rheumy said it was okay to keep taking them. I had no ill effects

and was in less pain before surgery.

Sue

Here's

> > > another POSITIVE thought about the results of hip

> > > surgery. I

> > > have never had so many compliments on how " good " I

> > > look and I don't

> > > attribute that entirely to the chunky vibrant red

> > > streaks I had put

> > > in my hair. I think living without pain has changed

> > > my whole

> > > countenance and I know it has changed my posture. I

> > > am passing this

> > > along to give heart to those who are reluctant,

> > > scared, whatever, as

> > > something to focus on.

> > >

> > >

> > >

> > >

[Guest guest]

Aspirin is the only NSAID that permanently makes the platelets less

sticky and the blood thinner. All the other NSAID's blood thinning

affect wear off very quickly (one to two days) .

Larry

At 03:52 PM 5/22/2004 +0000, you wrote:

It seem alot of Ortho docs are old school and any NSAID in their

minds thin the blood. Better safe than sorry. But they are

not the

ones in pain! So when the ortho's PA told me to stop, I said

no. My

Rheumy said it was okay to keep taking them. I had no ill effects

and was in less pain before surgery.

Sue

Here's

> > > another POSITIVE thought about the results of hip

> > > surgery. I

> > > have never had so many compliments on how " good "

I

> > > look and I don't

> > > attribute that entirely to the chunky vibrant red

> > > streaks I had put

> > > in my hair. I think living without pain has

changed

> > > my whole

> > > countenance and I know it has changed my posture.

I

> > > am passing this

> > > along to give heart to those who are reluctant,

> > > scared, whatever, as

> > > something to focus on.

> > >

> > >

> > >

> > >

[Guest guest]

Several years ago, I stopped taking Vioxx because it caused my blood pressure

to increase after only one month. It also caused edema, first in just my left

leg...which indicates that one might have a heart condition. My doctor had a

hard time controlling my blood pressure, even after I was off the Vioxx. It

took over a year to find the right medicines to bring it down to tolerable

levels. Interestingly, my blood pressure has gone down to where I'm having to

decrease the dosage of high blood pressure meds since I've been on Methotrexate

and

Humira. I don't know whether these two drugs had an effect on my blood

pressure, but I can't explain the drop except for the addition of these two

drugs.

I remember our group had many discussions on Vioxx when it first came out and

so many of us switched to this drug instead of others. It was supposed to be

safer. Best regards, Connie

[Guest guest]

Sounds like 18 months of treatment is the key for Vioxx. That is roughly the

amount of time it took to cause major health problems for me. It took well over

a year to get things back to normal. Or at least what I think is normal.

It may be a case of a great drug that can only work short term.

I agree with Ray, there have been too many " wonder " drugs for our diseases that

were rushed to market only to find that long term use of them was deadly. That

is why the Head of Rheumatology in Edmonton did trials with an old drug

Pamidronate but using a different delivery method. Pulse Pamidronate treatments

worked for many in the trials but not everybody.

I expect that we will see other " arthritis " wonder drugs go the same way.

+Dave

[Guest guest]

Regarding the Vioxx . . . I don't understand why everyone on this board is

upset about the vioxx. I was under the impression that nobody took it

anymore. Didn't news come out 6 or so months ago that Vioxx xauses ullcers

and other stomach problems? I know I absolutely won't take it. Was anyone

else banning Vioxx prior to this news, or is it just me?

Just Curious,

(Used to be TeacherGator!!)

June 20, 2000 - 283 & size 26/28 (basically a king size sheet!)

Currently - @140 (+/- 5 3-5 lbs anytime) size 6 / 8 in some brands

PS - I hvae been steady at my weight for 2 years, but I still got a kick out

of this: There was a clearance sale at Target on summer clothes. My son is

7, so I was loading up on shirts and shorts for him - I saw some clothes

that looked so much the size of my stuff . . . so I bought some shirts and

shorts (from the LITTLE BOYS section) and THEY

FIT!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! My son thinks it is

so funny that we match! I got 2 shirt designs in medium for him and XL for

me - so we will have to be careful putting laundry away! I told him whenever

he is ready he can look through my closet and borrow any of my skirts and

blouses . . . he didn't find that as funny as I did!! : ) LOL

[Guest guest]

Hi , I loved your post! How exciting to be able to buy clothes that

size, but I love your humor and your relationship with your son is refreshing!

You ROCK girl! I have lost 107 lbs, but am pretty sure I've lost my permanent

weight at 163. I wear a size 14, which I don't mind after being a 26, and I

am sure once I have tummy surgery I will be able to wear size 12's. Anyway,

my life is sure tremendously better after surgery and I'm so glad I did it!

No, I had not read about Vioxx being bad prior to their pulling it off the

shelves. I took it occasionally for pain, arthritis, but have always tried to

stay off meds if I could suffer through without them. I do know that Vioxx was

the only thing for pain recommended by clos until this recent news. I guess

you have to pick the lesser of the evils sometimes.

Anyway, I just wanted to let you know how much I enjoyed your post!

Suzanne H.

7/17/03

High Point-Dr. R and Dasher

270/163

[Guest guest]

Thanx for the post, . Interesting thing is they have known of

the link to colon cancer for 2 years...

Dennis Nowack DC

> Doctors:

>

> In case you haven't heard, Merck pulled its medication VIOXX from

> distribution yesterday. Please alert patients. I am not, and do

not

> expect to become, involved in any litigation regarding this

matter. I

> am simply posting the information in case you have patients who

you

> know to be using this medication.

>

> Respectfully,

>

> DeShaw, D.C., J.D.

[Guest guest]

celebrex is what you take now. barb dudley

[Guest guest]

Celebrex 200 mg

[Guest guest]

Is it any better than the vioxx? It did nothing for pain for me.

Cami in IN

264/144

26/6

Re: VIOXX

>

>

> Celebrex 200 mg

>

>

>

[Guest guest]

Celebrex.

>

> From: " Sharon " <ladymoe@...>

> Date: 2004/10/11 Mon PM 08:41:36 EDT

> < >

> Subject: VIOXX

>

>

>

> Has Dr. R mentioned anything to replace vioxx?

>

>

> Sharon

> 11/02

> 278/134

>

>

[Guest guest]

Hi Sharon,

CLOS is now using Celebrex 200 mg i a day has needed for pain.

Debbie Pennell,RN CLOS

Office 704-871-0031

Cell 704-682-2145

Sharon wrote:

>Has Dr. R mentioned anything to replace vioxx?

>

>

>Sharon

>11/02

>278/134

>

>

[Guest guest]

Vioxx? Since its been removed from sale what are

you taking now?

Bextra. It doesn't work as well as Vioxx, but much better than

Celebrex. It also took over a week to get full effect after the change.

[Guest guest]

I use Arthrotec. My doctor felt it safer because it's absorbed in the

intestine not the stomach. I find it more effective than Vioxx anyway.

It's the same active ingredient as Voltaren, diclofenac. But it's not

safe for a woman who may become pregnant, may cause birth defects.

bettylou

[Guest guest]

I used to take Vioxx a few years ago. I had to switch because it

caused stomach ulcers. Celebrex did nothing for me. I went to Bextra

and the pain disappeared. However, it caused HORRIBLE nightmares,

insomnia and hallucinations.

> Does anyone on this list take Vioxx? Since its been removed from

sale what are you taking now? My Mother and I are having no luck with

Celebrex, first it doesn't work as well as Vioxx, secondly its

constipating us. Relefen was suggested but we know nothing about it.

Thanks for any suggestions, Doug

>

>

[Guest guest]

I never had nightmares,insomina and hallucinations from taking Bextra. I take

first thing in the morning and with in 30 mins I am feeling better.

I recomended my brother-inlaw to take it who has had problems with meds and he

likes it better than vioxx and he has been taking it a month now.

I took neurotin and quit a year ago because it was causing severe side-effects.

Kendra <kendra@...> wrote:

I used to take Vioxx a few years ago. I had to switch because it

caused stomach ulcers. Celebrex did nothing for me. I went to Bextra

and the pain disappeared. However, it caused HORRIBLE nightmares,

insomnia and hallucinations.

> Does anyone on this list take Vioxx? Since its been removed from

sale what are you taking now? My Mother and I are having no luck with

Celebrex, first it doesn't work as well as Vioxx, secondly its

constipating us. Relefen was suggested but we know nothing about it.

Thanks for any suggestions, Doug

>

>

[Guest guest]

I was also on neurontin and it was a miracle worker until 7 months

after I started using it and it began causing horrible nightmares that

I would refuse to sleep because I was so scared. I've been on a lot of

the drugs related to those mentioned. Now I'm using Keppra and it has

been working well besides the increased depression.

> > Does anyone on this list take Vioxx? Since its been removed from

> sale what are you taking now? My Mother and I are having no luck with

> Celebrex, first it doesn't work as well as Vioxx, secondly its

> constipating us. Relefen was suggested but we know nothing about it.

> Thanks for any suggestions, Doug

> >

> >

[Guest guest]

keppra....to treat pain? I looked it up and the indication is for

seizures but I know it may have other indication not commonly mentioned.

Thanks,

Lori

Kendra wrote:

>I was also on neurontin and it was a miracle worker until 7 months

>after I started using it and it began causing horrible nightmares that

>I would refuse to sleep because I was so scared. I've been on a lot of

>the drugs related to those mentioned. Now I'm using Keppra and it has

>been working well besides the increased depression.

>

>

>

>

>

>

>

>

>

>

[Guest guest]

Keppra's main purpose is to treatment seizures, like Neurontin. They

both also work as chronic neural pain relievers - which is different

than Vioxx or Celebrex or Bextra which works as an anti-inflammatory

for the joints.

>

> >I was also on neurontin and it was a miracle worker until 7 months

> >after I started using it and it began causing horrible nightmares that

> >I would refuse to sleep because I was so scared. I've been on a lot of

> >the drugs related to those mentioned. Now I'm using Keppra and it has

> >been working well besides the increased depression.

> >

> >

[Guest guest]

Documents Reveal Vioxx Sales Tactics

Merck Memo Urges Reps Not to Mention Heart Risks to Doctors

By LAURAN NEERGAARD, AP

AP

An information card for doctors suggested that Vioxx could be safer than

other anti-inflammatory drugs.

WASHINGTON (May 6) - What Merck & Co. calls good salesmanship - emphasizing

the positive in selling the painkiller Vioxx - a Democratic congressman says is

disinformation designed to deflect safety concerns. The public got an

extraordinary glimpse Thursday into the world of drug marketing, as lawmakers

released confidential Merck documents that detail how a sales army of 3,000

aggressively pushed the multibillion-dollar drug before it was pulled from the

market

last fall because of heart attack risks.Instructions were as detailed as how

long to shake a physician's hand - three seconds - and how to eat bread when

dining with doctors - ''one small bitesize piece at a time.''Sales

representatives were offered $2,000 bonuses for meeting sales goals, and worked

in campaigns

with such code-names as ''Project Offense'' to try to boost sales even as

regulators were about to increase warnings on the drug's label.Don't bring up

the

heart risks, warns a Feb. 9, 2001, memo.And when doctors asked about those

risks, the Merck sales reps were to refer to a ''cardiovascular card'' with data

suggesting that Vioxx could be safer than other anti-inflammatory drugs. Yet

the card, also released Thursday, doesn't include the very study that raised

the first warning signal that Vioxx could harm.''The Cardiovascular Card is an

obstacle handling piece,'' says an April 2000 memo to Vioxx sales reps,

written just after the first heart-related research began trickling in. It

''will

allow you to set the record straight with your physicians.''

The documents were released at a hearing of the House Government

Reform Committee.Merck Vice President Dennis Erb defended the company's

handling of Vioxx, noting that it promptly released details of studies that

first

raised the specter of heart damage - and followed up by performing the study

that ultimately doomed the drug.''We believed wholeheartedly in the safety of

Vioxx and that Vioxx was an important treatment option,'' he said. ''My own

father was a regular user of Vioxx until we voluntarily withdrew it from the

market.''But even as scientific debate about Vioxx's heart risks began in 2000,

sales of the painkiller steadily soared, to $2.5 billion in 2003.''Why did

doctors

write so many Vioxx prescriptions even as evidence of harm mounted?'' asked

Rep. Henry Waxman, D-Calif.Sales tactics in directly promoting the drug to

doctors, he concluded: ''When it comes to the one thing doctors most needed to

know about Vioxx - its health risks - Merck's answer seems to be disinformation

and censorship.''Merck pulled Vioxx after a study showed it doubled the risk of

heart attacks and strokes in patients using the drug for more than 18 months.

Merck is facing more than 2,300 lawsuits from customers, and on Thursday its

chief executive, V. Gilmartin, stepped down. Merck named T.

to replace him.But many people say Vioxx offered relief that other drugs

haven't. So Erb told lawmakers the company has begun discussions with the Food

and Drug Administration about what it could do to return the drug to pharmacy

shelves.''We're now in preliminary discussions,'' he said.FDA's scientific

advisers in February narrowly voted that Vioxx might be able to come back onto

the market under certain conditions, such as restricting its use to patients

with severe pain or loading it with strong warnings about the heart risk.That

risk first appeared with research released in 2000 and 2001, showing certain

Vioxx users suffered twice as many heart attacks and other cardiovascular

problems

as users of the older painkiller naproxen. In 2002, the FDA added warnings to

Vioxx's label.At first, scientists thought it might be because Vioxx users

weren't getting a blood-thinning benefit that comes with many older painkillers.

But by 2002, top specialists were worried that Vioxx might be the direct

culprit - and Merck's own follow-up research prompted it to pull the drug.FDA

drug

chief Dr. Galson told lawmakers that the agency is taking steps to

improve awareness by the public and doctors of potential drug risks as soon as

they arise.He said that what was happening with Vioxx wasn't clear-cut until the

research was completed last summer. He acknowledged, however, that it may

have taken too long to put a new warning label on the drug.''We think we've

addressed the sort of problems that happened here, and to make sure it won't

happen

again,'' Galson said.Waxman tried to focus attention on the sales

representatives, arguing that ''the goal was sales, not education.''Rep. Tom

,

R-Va., the committee chairman, said the new documents raise questions about

Merck's

handling of Vioxx. But he said he was not prepared to criticize the company

without more information, noting that Merck made public results of its own

studies that raised the concerns - data subsequently widely published, in

medical

journals and newspapers.''A wide-awake physician would have obviously known

about this?'' asked.''That is correct,'' Erb responded.But another

witness, Dr. Wilkes, vice dean for medical education at the University

of

California-, said physicians are busy and look for shortcuts to get

information. ''Doctors don't read the medical literature,'' he said, and often

rely on

the salesman they meet in their office.---Associated Press Writer

Freking contributed to this report.AP-NY-05-06-05 0640EDT

Marhoefer

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[Guest guest]

I am so sorry people had serious reactions to Vioxx. It is very tragic to have

a drug reaction, but that is more often the case than not. I was one who did

very well with Vioxx, took 12.5 to 25 mg per day only, but it took away the

aches of FMS that ibuprofen doesn't really touch. I can't take Celebrex because

of sulpher allergies, but it has risks now, too. So I stick with Vicodin in

small doses when I can't stand the pain. And why do some of the healthiest of

us have the most problems? My son is always saying, " Mom, if you do all that

you are doing and take all those healthy things and eat so healthy, what chance

do we have of staying well? "

in La Selva Beach CA

Re: One Million Sickos Forgotten

On Feb 4, 2006, at 7:11 AM, Kurt R. wrote:

> Sara,

>

> I love this letter, and hope you don't mind if I fwd it to my family,

> this explains what I have been trying to say to them for years, but

> much

> more dramatically..

>

> BTW, my background is related a bit to this type of project, I am a former

educational researcher and have written scripts for multimedia productions. I

like your spin on this issue, I would also mention the new CFS-type illnesses

among people who helped with the 911 clean-up, and also GWI.

>

> I imagine MM is after the pharmaceutical cartel, so he probably is going> to

try and expose the truth about the Vioxx scandal and government involvement

(particularly the lackadaisical attitude of he current administration in not

holding the industry accountable for 60,000+ deaths).

I'm good with that, too. My robustly healthy 66-year-old mother, who weighed

130 pounds, exercised four times a week, had her cholesterol under firm control,

and ate a diet that was a cardiologist's dream -- in other words, was nobody's

candidate for heart problems -- had a heart attack five months after starting on

Vioxx.

She's fine now; her most recent exam showed no damage at all. But it was a

year she didn't need to spend recovering from something so avoidable.

She is party to some of the lawsuits that have been going on. Go,

!

Sara

This list is intended for patients to share personal experiences with each

other, not to give medical advice. If you are interested in any treatment

discussed here, please consult your doctor.

[Guest guest]

I used to have screaming, roll on the floor pain that nothing, including

vioxx, touched except for valium and vicodin..... but their side effects were

not good.

I was amazed the pain relief that came fairly fast when I finally found the

right dose and kind of Magnesium my body needed.

Make mine a simple mineral from now on. I still have nuisance pain, but the

intense pain and related Magnesium deficieny problems are greatly improved

too.

Over ten years of agony significantly relieved by MoM and it's B6 cofactor.

Hope this helps

In a message dated 2/4/2006 11:52:53 PM Eastern Standard Time,

schmidtmba@... writes:

I was one who did very well with Vioxx, took 12.5 to 25 mg per day only, but

it took away the aches of FMS that ibuprofen doesn't really touch. I can't

take Celebrex because of sulpher allergies, but it has risks now, too. So I

stick with Vicodin in small doses when I can't stand the pain. And why do

some of the healthiest of us have the most problems? My son is always saying,

" Mom, if you do all that you are doing and take all those healthy things and

eat so healthy, what chance do we have of staying well? "

in La Selva Beach CA

mjh

" The Basil Book "

http://foxhillfarm.us/FireBasil/

[Guest guest]

Ellen

MoM = Milk of Magnesia = Magnesium hydroxide.

Hope this helps

mjh

In a message dated 2/5/2006 9:41:58 AM Eastern Standard Time,

ellenelle@... writes:

mjh,

What form of magnesium is in MoM?

Thanks,

Ellen

mjh

" The Basil Book "

http://foxhillfarm.us/FireBasil/