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Lungs + NF-kappaB

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Lungs + NF-kappaB

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Hepatitis C virus core protein enhances NF-kappaB signal pathway triggering

by lymphotoxin-beta receptor ligand and tumor necrosis factor alpha. PMID:

9882379

Lung Dysfunction in an Animal Model of Asthma. Kinetics of NF-kappaB

activity is strongly related to the course of the disease and confirm the

relevance of NF-kappaB as a putative target in asthma therapy. Moreover,

uncommon p65 homodimers could transactivate, in BCs [broncial cells], a

subset of genes, such as ICAM-1[intercellular Adhesion Molecules],

characteristic of chronic airway inflammation. PMID: 10764329

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