Guest guest Posted January 20, 2008 Report Share Posted January 20, 2008 Each of the three TNF blockers works on the same part of the immune system but in different ways so maybe one will work while the others may not. Also the body can reject one and stop responding to that one, but may respond well to one of the others. I hope you find a way to get relief. God bless. From: Rheumatoid Arthritis [mailto:Rheumatoid Arthritis ] On Behalf Of Sent: Saturday, January 19, 2008 5:45 AM To: Rheumatoid Arthritis Subject: [sPAM] Rapid Decline, Permanent Deformity Hi All, I have had RA for 5 years and have taken Humira for about 4 and now it has stopped working for me. Not only that, my RA is attacking me so aggressively that I now have permanent damage and deformity with the worst part being that it looks like I have bunions coming out of my first fingers on both hands This is especially scary because a month ago my hands did not look like this!!! I don't understand this rapid damage, when in the beginning I was undiagnosed for 6 months with no permanent damage. This is very hard to wrap my mind around as I believed due to the new classes of drugs for RA that I would never have permanent damage or deformity. Also as a woman, I think it is tough from a vanity standpoint. I would like to hear from others out there who have experienced this and if anyone has had this happen so quickly. Until I find something that works for me, what am I going to look like next month or next week? I have a 16 month old so resting my joints is not much of an option. I want to be a normal mom to him; be able to lift him and play with him. Also, MTX is not desireable to me since I am still of childbearing years. Thanks and love, Quote Link to comment Share on other sites More sharing options...
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