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Hi Kathy,

As your doc says, floaters are common with aging, and not related to

Gleevec. They're a nuisance (I have a ton of them because I'm very

nearsighted, which IS a risk factor for them), but they tend to fade in

time, fortunately. I had a skiing accident last summer, in which I hit my

head, causing a ton of new floaters - but I barely notice them now.

Best,

R

> Date: Wed, 14 Sep 2005 10:43:07 -0000

> From: " kathydf47 " <kathydf47@...>

> Subject: eye issues

>

> Hi everyone -- I've been on gleevec for a bit over 2 years now.

> Chugging along & doing quite well. I recently have eye 'floaters'

> --

> I think they're called vitreous floaters. Little pieces that pull

> away from the eye & 'float' until they finally detach. My

> opthamologist said that they are quite common as we get up there in

> years <sigh> -- but I'm wondering if anyone else suspects these are

> connected with gleevec. I had one in my right eye, and now have one

> in

> my left eye. I will have to have them checked periodically to make

> sure they are not pulling too hard on the retina -- and they are

> somewhat annoying -- but certainly something I can live with -- I'm

> not

> complaining, just curious. Any input? Thanks!

>

> peace,

> Kathy

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At 09:42 PM 9/14/05 -0400, you wrote:

>Hi Kathy,

>

>As your doc says, floaters are common with aging, and not related to

>Gleevec. They're a nuisance (I have a ton of them because I'm very

>nearsighted, which IS a risk factor for them), but they tend to fade in

>time, fortunately. I had a skiing accident last summer, in which I hit my

>head, causing a ton of new floaters - but I barely notice them now.

>

>Best,

> R

Hi and Kathy,

Gee ....near sighted and getting older...sounds like me too!!

I did have 2 vitreous hemorrhages that Dr. D 'agreed' (with eye doc) was

probably Gleevec related........but this was not simply a few little

floaters. When it happened it was like an entire spider web in front of my

eye. Apparently vitreous hemorrhages have been listed as a Gleevec side

effect, but rare. I think maybe Margo from the list has also had this

happen. It took a number of months for this to fade, but it was checked out

twice and they did not see the source of the bleed.

C.

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Hi Nanc - nice to hear from you.

Vitreous hemmorhages and IM makes sense. Sorry you've experienced it

though. It must have been upsetting the first time.

My last shower of floaters resulted from a mild head injury while I was

skiing last winter. I just figured it was the vitreous humor pulling away

from the retina a little more than it had already done. This is the main

cause of floaters.

Love,

R

> Gee ....near sighted and getting older...sounds like me too!!

>

> I did have 2 vitreous hemorrhages that Dr. D 'agreed' (with eye doc) was

> probably Gleevec related........but this was not simply a few little

> floaters. When it happened it was like an entire spider web in front of my

> eye. Apparently vitreous hemorrhages have been listed as a Gleevec side

> effect, but rare. I think maybe Margo from the list has also had this

> happen. It took a number of months for this to fade, but it was checked out

> twice and they did not see the source of the bleed.

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Hi Kathy,

I had floaters a year before I was dx'd and then developed a macular

hole in my left eye. I also had a eye hemmorage a month ago. All in

the left eye. This I am sure is related to Gleevec. If the floaters and

macular hole was related to CML no one can say. I feel since I had no

eye issues at all in the past only a small correction, it is all

related to CML. My eyes are always watery and swollen. Small price to

pay so far. I feel for you floaters are very disconcerting. Hope this

helps.

Joan

dx'd 8/03

Gleevec 400mg

Zavie #667

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> Hi Kathy,

> I had floaters a year before I was dx'd and then developed a macular

> hole in my left eye. I also had a eye hemmorage a month ago. All in

> the left eye. This I am sure is related to Gleevec. If the floaters

and

> macular hole was related to CML no one can say. I feel since I had no

> eye issues at all in the past only a small correction, it is all

> related to CML. My eyes are always watery and swollen. Small price to

> pay so far. I feel for you floaters are very disconcerting. Hope this

> helps.

> Joan

> dx'd 8/03

> Gleevec 400mg

> Zavie #662

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I don't know what the issues are or why they're revealing themselves but i've

been fortunate enough not to experience any (thank-god) but I find that water is

a vital importance for every-'Body'. I drink plenty of it even when I don't want

to and just to cleanse the liver of it's intoxiants is a good thing. I don't

know if this correllates to any thing but if you're not drinking more than the

average (non-CML) person, then I would suggest you do. I know I do. Now, I've

only been on Gleevec for 3 years but I've only had the leg/feet cramps and the

legs cramps have ceased since I began drinking lots of water.

Just a thought...Good Luck!!

Key

cellphonejoan <joanfporter@...> wrote:

Hi Kathy,

I had floaters a year before I was dx'd and then developed a macular

hole in my left eye. I also had a eye hemmorage a month ago. All in

the left eye. This I am sure is related to Gleevec. If the floaters and

macular hole was related to CML no one can say. I feel since I had no

eye issues at all in the past only a small correction, it is all

related to CML. My eyes are always watery and swollen. Small price to

pay so far. I feel for you floaters are very disconcerting. Hope this

helps.

Joan

dx'd 8/03

Gleevec 400mg

Zavie #667

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  • 3 years later...

How interesting about the eye allergies. As a college student, I spent every Easter break in the Eye Clinic on campus, because my eyes were so irritated. Vasacon, and similar meds never took care of them, but the caution against steroid drops made every doctor put me on conservative meds first. My eyes ALWAYS went on to need steroid drops, which cleared them up rapidly, but often not until the swelling ulcerated the cornea. But one time, they noted Iritis, which they said went along with connective tissue diseases. BUT, I had always been seronegative, and repeatedly told I did NOT have RA, until a major knee issue after having a kidney stone and sepsis. Since then, MTX and NSAIDS have held things in check. I have been on three research protocols, with

not much benefit from the major biologicals, which my insurance will not cover. Has anyone else had significant eye issues?Usually, I am a silent reader, but this really hit my case. Thanks for sharing. Fatigue and pain have to be my major issues, but usually tolerably controlled.Prairiegrandma

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  • 2 weeks later...

I find a humidifier makes a big difference. Here in AZ the air is so

dry that my eyes are very uncomfortable. Lubricating eye drops help

for a while, but running a humidifier and keeping the relative humidity

at about 40 percent or so makes a big difference. (Around here the

average RH runs 7 to 12 percent!)

Sharon

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  • 1 month later...

>> I find a humidifier makes a big difference. Here in AZ the air is so > dry that my eyes are very uncomfortable. Lubricating eye drops help > for a while, but running a humidifier and keeping the relative humidity > at about 40 percent or so makes a big difference. (Around here the > average RH runs 7 to 12 percent!) > > Sharon>I don't know how to add on to an e-mail. I am on Restasis for the dryness and also I have plugs in my eyes which really help me out.

I think they are going through a really dry state right now. Thanks for the humidifier suggestion. Elaine

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  • 2 years later...

I thought I should interject here so everyone will realize what has occurred.

Sinus infections and involvement (bacteria and fungi), particularly the

maxillary and ethmoid areas, will allow the toxins and in some cases the

microbes to enter the intraocular orbit as well as the optic nerve area. This

invasion can lead to visual ;problems and optic neuritis.

[] Re: Eye issues

Hi Kathy,

Yes! You aren't alone! I had those symptoms too. With re-exposure it comes

back sometimes. I hope an eye doc can help you. That wasn't the case for me

though. Only CSM, exposure avoidance, & Dr Shoemaker's protocols helped in my

case.

Debbie H

>

>

> It must be awful having optic neuritis.

>

> Do any of you have over sensitivities to colors? I have pain looking at

bright

> colors that's getting worse. Vivid colored paper or neon colors hurt.

>

> Nothing was seen on a reg. exam. I better see a medical eye doc.

>

> Kathy

>

>

>

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makes sence to me, sometimes it ties in with my sinuses, pain/inflammation other

times it ties in with head pain,inflammation.

I get frontal headackes sometimes that I relate to my sinuses, but worse are

the migranes that go up the back of my neck and are basicly full head migranes,

scalp can get pretty tender with these, these usually involve a stabbing pain to

the back of my eyeball that

hurts like heck along with pressure,ect. in,around the eye.

--- In , " Jack Thrasher, Ph.D. " <toxicologist1@...>

wrote:

>

> I thought I should interject here so everyone will realize what has occurred.

Sinus infections and involvement (bacteria and fungi), particularly the

maxillary and ethmoid areas, will allow the toxins and in some cases the

microbes to enter the intraocular orbit as well as the optic nerve area. This

invasion can lead to visual ;problems and optic neuritis.

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