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Di,

The mtx depletes the folic acid in your body which is why it is given

w/mtx. You would notice your hair and nails for sure w/out the folic

acid.

I've never taken celebrex so can't help you there.

Nanc

Dianne Ohlmus wrote:

> Hi everyone,

> Have read that Folic acid is recommended for those who take MTX. What

> does

> it do?

> Also I am just on Celebrex and have been feeling ghastly on it. My

> teeth

> have been chipping and legs, neck,shoulders and lower back ache. Is

> this

> from the Celebrex or is it the PA? This disease is so confusing!

> Di

> Canberra. Australia.

>

>

>

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Folic Acid with the MTX is to protect your stomach from deteriorating. You

should never take MTX without it. If your MD doesn't know this, get another MD.

I couldn't tolerate Celebrex either. After a few months I just switched to

Viox. It's basically the same type of drug, a 2 inhibitor, but I have fewer

side effects ( heartburn especially) on it. The problems you are describing may

be from the MTX. I couldn't tolerate it. They don't tell you that 75% of

patients cannot tolerate the stuff after 3 months, even when injected. MTX is a

chemotherapy drug and very toxic. Read the prescription package insert. Ronnie

E.

[ ] re Folic acid

Hi everyone,

Have read that Folic acid is recommended for those who take MTX. What does

it do?

Also I am just on Celebrex and have been feeling ghastly on it. My teeth

have been chipping and legs, neck,shoulders and lower back ache. Is this

from the Celebrex or is it the PA? This disease is so confusing!

Di

Canberra. Australia.

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Thanks for your reply. Yes my hair has been falling out and my nails are

splitting and big toenails lifting.

Even though I am not having MTX would you recommend Folic Acid because of

these symptoms?

Di

At 14:30 14/07/2001 -0400, you wrote:

>Di,

>

>The mtx depletes the folic acid in your body which is why it is given

>w/mtx. You would notice your hair and nails for sure w/out the folic

>acid.

>

>I've never taken celebrex so can't help you there.

>

>Nanc

>

>

>

>Dianne Ohlmus wrote:

>

> > Hi everyone,

> > Have read that Folic acid is recommended for those who take MTX. What

> > does

> > it do?

> > Also I am just on Celebrex and have been feeling ghastly on it. My

> > teeth

> > have been chipping and legs, neck,shoulders and lower back ache. Is

> > this

> > from the Celebrex or is it the PA? This disease is so confusing!

> > Di

> > Canberra. Australia.

> >

> >

> >

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Dianne,

I'd never play Dr. here so I suggest you check w/him first. Folic acid

can be bought off the shelf. Folic acid would more than likely help

your hair loss and nails. I'd just ask physician about amounts and

should you have an Rx for what dosage you should take. I take a Rx and

it is very inexpensive.

Nanc

Dianne Ohlmus wrote:

> Thanks for your reply. Yes my hair has been falling out and my nails

> are

> splitting and big toenails lifting.

> Even though I am not having MTX would you recommend Folic Acid because

> of

> these symptoms?

>

> Di

>

>

> At 14:30 14/07/2001 -0400, you wrote:

> >Di,

> >

> >The mtx depletes the folic acid in your body which is why it is given

>

> >w/mtx. You would notice your hair and nails for sure w/out the folic

>

> >acid.

> >

> >I've never taken celebrex so can't help you there.

> >

> >Nanc

> >

> >

> >

> >Dianne Ohlmus wrote:

> >

> > > Hi everyone,

> > > Have read that Folic acid is recommended for those who take MTX.

> What

> > > does

> > > it do?

> > > Also I am just on Celebrex and have been feeling ghastly on it. My

>

> > > teeth

> > > have been chipping and legs, neck,shoulders and lower back ache.

> Is

> > > this

> > > from the Celebrex or is it the PA? This disease is so confusing!

> > > Di

> > > Canberra. Australia.

> > >

> > >

> > >

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In a message dated 07/14/2001 5:08:30 PM Eastern Daylight Time,

ronevans@... writes:

<< They don't tell you that 75% of patients cannot tolerate the stuff after 3

months, even when injected. MTX is a chemotherapy drug and very toxic. Read

the prescription package insert. >>

Ronnie - I agree wholeheartedly that's it's a potent and potentially

dangerous drug. And we should read inserts, but My God!, we'd never take

another drug if all those things in the inserts happened to all of us. Thank

goodness most side effects are relatively rare.

I don't know if I agree with the 75% being unable to tolerate after 3 months.

I'd be interested to know where this statistic comes from. Also, our dose

is far lower than a chemo patient, so maybe they were including chemo

patients in that study. I think a lot of us on here have been on MTX for

years. I have been on over 2 years and I have a lot of drug sensitivities.

Yes, it upsets my stomach, but I've learned to deal with it. I think some

drugs take time to not only work, but to be able to tolerate as well, and for

me, it took a few months to adjust to MTX. The pills, I couldn't handle, but

injections were tolerable.

As always, everyone is different, and MTX is a personal decision all of us

must make.

Just my 2 cents -

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In a message dated 07/14/2001 11:11:44 PM Eastern Daylight Time,

ohlmus@... writes:

<< Yes my hair has been falling out and my nails are

splitting and big toenails lifting.

Even though I am not having MTX >>

Di - it seems to me that the nails are probably related to P and perhaps the

hair too if your scalp is very bad. But if not, you really need to see a

doctor. Thinning hair can be a sign of other problems such as thyroid, or

many other things.

I don't think that hair falling out is necessarily a result of PA.

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  • 1 year later...
Guest guest

If your pain is " nerve pain " can a neurologist or neurosurgeon check to see if

your deteriorating condition could be presssing on a nerve root.....that pain is

awful, awful...but it can be helped greatly with minimal back surgery to remove

the spur that is encroaching on the nerve root. You may still have some pain

for several months even after surgery because the nerve takes time to calm down.

Best wishes!!! Sylvia

" w.fitzgibbon " <w.fitzgibbon@...> wrote:Hi everyone, I visited my

rheumy yesterday still wont put me on folic acid .I had bad results on blood

work so he may change meds also thinks i have ankylosing spondylitis or

something else he is waiting for test results if he doesent ease pain i will go

crazy. Regards

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Hi everyone, I visited my rheumy yesterday still wont put me on folic

acid .I had bad results on blood work so he may change meds also

thinks i have ankylosing spondylitis or something else he is waiting

for test results if he doesent ease pain i will go crazy.

,

Any supermarket or vitamin outlet has folic acid. I take only 1 mg

per day. Find the equivalent dosage at a local store. Also, I have

been on MTX for 7 or 8 months with absolutely no relief or side

effects and I find it actually a little bit more effective when I do

not use Folic Acid, especially on my MTX dosage day. Good luck. I

see my rheumy tomorrow and hope to be on Enbrel when I leave!

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  • 2 years later...

I would really like to see some " real " proof of this statement. My Rheumy stated

very clearly that folic acid is taken because meth affects the absorption of

folic acid. It does not work the other way, ie. that folic acid affects the

absorption of meth. He recommended that I take 5mg every day. He is a very

highly regarded rheumy, and not just by me.

btw..Not that I want to start an argument..I am just very interested about this

one.

Dave H

[Editor's Note: I specifically asked my rheumy about this some time ago (he's

the head of rheumatology at a major NYC teaching hospital) and he said that the

post below was the old way of thinking based on the quantity of MTX and folic

acid involved in cancer treatments. The quantities involved in the treatment of

PA are so small in comparison that studies repeatedly have shown that there is

no reason NOT to take folic acid on the day you take MTX. Ergo, my doctor agrees

with yours. When we have had this discussion in earlier threads, I didn't

really see evidence that " most " docs recommend not taking folic acid on MTX day.

Kathy F.]

[ ] Re Folic Acid

It stops the action of the methotrexate That is why most docs will tell you

to skip it on the day of your shot/pills. There is quite a bit of

discussion in the archives of the list about this if you are further

interested.

S

group founder

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  • 3 years later...

Hi ,

The reason you aren't supposed to take folic acid on the same day as methotrexate is that it reduces the effectiveness of the drug in your system.( That's what my RA doc told me).

It's okay to take the folic acid the next day though.

Misty

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  • 2 months later...
Guest guest

I agree with Misty in part because Folic Acid does reduce the

effectiveness of Methotrexate, but this effect is so small and Methotrexate is

not very expensive that most doctors in the US seem to prescribe Folic Acid

every day. The dose of Methotrexate is an arbitrary amount depending on

patient reaction so I take Folic Acid daily to avoid the side effects. God

bless.

From:

Rheumatoid Arthritis

[mailto:Rheumatoid Arthritis ] On Behalf Of misty

thornton

Sent: Friday, February 13, 2009 3:31 PM

Rheumatoid Arthritis

Subject: Re Folic acid

Hi ,

The reason you aren't supposed to take folic acid on

the same day as methotrexate is that it reduces the effectiveness of the drug

in your system.( That's what my RA doc told me).

It's okay to take the folic acid the next day though.

Misty

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08:12:00

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