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Carol, our MTX use is nowhere near the dose given for cancer

treatment. Most people don't experience any hair loss. Most of those

who do find it is minimal and temporary. Relax.

regards,

sherry z

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I don't really have any side effects. The hair loss, if any, is minor. The

dose for treatment of PA typically isn't as large as cancer patients, so

hair loss is minimal -- if any.

Just be sure to take the folic acid as prescribed. That helps reduce any

side effects as well.

I also take my dose of MTX before bed. That ensures that any minor nausea

(which I'll have once in a great while) won't be an issue since I'll be

asleep. I take it on Saturday night before bed -- just in case I have any

issues the next day. But typically I don't have any problems.

Sometimes it does open you up to more issues with bronchitis or sinus

infections. Just be sure to have any colds or congestion treated

immediately so that they don't get worse. For example, I didn't treat my

last sinus infection fast enough and it got worse fairly quickly. A good

round or two of antibiotics did the trick and now I'm fine.

My best friend has cancer and so I really feel for you and your sister.

Hang in there! But don't worry. MTX for PA is NOTHING like chemo for

cancer.

Good luck!

Patty

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  • 4 months later...

, I have lots of elbow pain with my PsA. AS a matter of fact they

don't even straighten all the way anymore. But I can't tell you if MTX

will help, I'm supposed to start it later this week. Never had it

before. The nurses did tell me to expect to be a little nauseated when

I first start taking it, they didn't mention light headed tho.

Hope you feel better soon.

Penny

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Don't know if this well help or not. But when I was on MTX, my Rheumy

had me take it on Friday nights before I went to bed. That way, I would

be asleep should any of the side effects happen.

I will say that it did help. I did have a Saturday hangover from it.

The only time that it got bad was when I upped the dosage and I felt

like I got him by a freight train the next day.

I will also say that it did get better with time.

Hope that this helps,

Ella

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Hey , do you mean methotrexate (MTX)? I hate it! I inject 25 mg into my leg

every Tuesday, and maybe I can eat food by Thursday evening. by then, hopefully

the diarrhea subsides as well.

I've noticed more recently that it seems to make me feverish and tired, as well

as edgy and irritable. I've been on it about a year and a half, and have started

probiotics and glutamine to strengthen my digestive system. I hope it helps. If

I witness just one more doctor who innocently responds to my distaste for this

drug with " but it's just G.I. , right? " I might just poop on him....

" traumacide " <traumacide@...>

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  • 4 months later...

Hi ,

> My rheumy just ordered Mtx and folic acid. I am very afraid to try it

> but I am in so much pain.

You have to try it.

> He doesn't have the bedside manner to discuss things with me.

Then find another, or if you really trust him despite that, follow his

recommendations and discuss things here on the forum!

> He is a top rheumy and recommended but I guess I just can't

> believe at my age -- 43 -- I can have osteo, PsA and fibromyalgia?

Yes, you can. I don't say you necessarily DO, but you CAN. It's not

uncommon.

> What have been the side effects people have

> experienced with MTX, I am a poster child for drug side effects!

I started MTX very recently. Last Friday I took my second dose. So far,

for me the side effects are very slight nausea and very slight flue-like

symptoms (runny nose, bronchial irritation, pain in the forehead), but

really very slight, not a problem at all. They have lasted for a full

day after each dose. If it doesn't get worse, it won't be an issue at

all. Of course, in another several weeks they will check my liver to see

if it is taking the MTX well enough. And it remains to be seen whether

the MTX helps me at all. So far it hasn't, but that's no surprise

because it's slow to develop its positive action.

Manfred.

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Yes, it's typical to take the entire dose at one time weekly. However,

many find that splitting the dose into two batches taken on the same

day alleviates some of the side effects. I used to take half my dose

on Friday morning and the other half on Friday night, along with Zantac

and Benadryl. This made me not feel nauseous or flu-like or so

fatigued. If you daughter is having unpleasant side effects, you can

ask her doctor about splitting the dose and taking the other things to

help. I've never heard of a rheumy objecting to this method.

" S. Zorzi " <szorzi_1999@...>

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Sd I was on MTX injections and it gave me upset stomach and I did

get sores on the outside of mouth.But of course not every one else is

the same just thought I would write. I had no luck with MTX. Was still

in a lot of pain.

" " <masseytdm@...>

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My son started MTX taking 6 pills/week all at the same time. 6

weeks later we switched to the injection when the pills weren't

doing much. With the injection, more of the drug gets into your

blood stream and doesn't sit in your stomach. As his dose was

gradually increased he had more stomach problems. Now we are back

down to 10 mg/week and our rheumy has stated that 10 mg is as low as

you could go. Any lower than that and it won't do anything.

& Grant (11, PsA/Uveitis)

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  • 1 year later...
Guest guest

WOW, you must be tough! I started with those almost immediately when I started

MTX.

But there is help. Folic Acid, which is cheap, has few side effects, and is

easy to take. Ask your rheumy, but mine has me go as high as a gram twice a

day. Taking it like candy, my mouth sores are almost a thing of the past!

Prairiegrandma

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  • 1 month later...

I took it for six months and had no side effects. Don't automatically assume

you will have them. MTX has been around for years and is relatively safe as long

as your doctor does the required bloodwork on a regular basis to ensure that

your liver is not being affected. But avoid alchohol while you're on it. My

doc said " once a year, on your birthday " . The reason, obviously, is that

alcohol can also affect the liver and may increase the potential for liver

problems.

Joanna Hoelscher

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