Guest guest Posted January 31, 2000 Report Share Posted January 31, 2000 Hi , Josh started at 7.5mgs MTX weekly and we gradually increased the dose over time, up to 15mgs. Like I said in my other post, there seems to be some evidence that starting on higher doses earlier, with MTX and Plaquinel, may have better efficacy. They will probably do blood work every 4 to 6 weeks to monitor her liver functions and check the white blood cell count, and if there is anything out of the ordinary noted, maybe they'll decrease the dose a little or add some folic acid or suggest that she take it by injection, if it's to be given orally. MTX has been very helpful, for many people. I hope that n is among that group Also, the indomethacin has been the most effective NSAID for . He takes 25mg, twice a day. He has only tried 3 (indo, relafin, naprosyn) but this one works the best for him. He does take a cytotec pill with it each time though, as it's supposed to help protect the stomache lining. And it needs to be taken with food, too. Good Luck to n! Let us know how it goes. ~Georgina > From: " WILLIAM PRICE " <william.e.price@...> > The doctor said that if n had any bone > destruction in her wrists that she should start mtx right away. She > said that n would be given a dose of 25mg. Since Josh is around > n's age, I wondered if you thought that was a high dose to start > with, or if that sounded right to you? Also, has Josh had any > problems with indomethacin? n was just taken off of the naprosyn > and put on the other. Any insight would be helpful. Thanks, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2000 Report Share Posted September 22, 2000 in St. Louis, I was on MTX for a little over a year. We titrated my dosage up over that year to 17.5 mg/wk, and I stayed at that dosage for around 6 months, I think. I switched to injections at the 15 mg/wk point, because I didn't want to deal with the " attack diarrhea " anymore (sorry if that's a little graphic; however, it's an apt description). After I started the injections, that problem disappeared, and my system's response to the drug improved, I believe. I have read that MTX injections are better absorbed by the body, because the drug does not have to endure the rigors of absorption through the digestive tract. That appeared to be the case for me. Patty, moderator from OH PHDRWD@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2000 Report Share Posted September 22, 2000 Mark is up to 1 cc or 25mg per week, injections. He has far fewer side effects with the shots. I don't exactly remember when he switched, I think it was about 15mg per week. >I was curious as to what dosage of metho everyone was taking? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2000 Report Share Posted September 22, 2000 I started at 7.5mg and am now at 12.5mg and going up. I've never had a problem with nausea. This may be because: 1. I take it all at night before I go to sleep; 2. I take a daily extended release capsule of Prevacid,(antacid); 3. Or I'm just extremely lucky. I should also say that " so far " the MTX hasn't had much positive effect either. I think it's all up to the individual taking the medication as to how well their body can handle the side effects. Unfortunately, you have to give it a try before you'll know. Think positively! Jay Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 25, 2000 Report Share Posted September 25, 2000 >in St. Louis, MO wrote >I was curious as to what dosage of metho everyone was taking? And at what > >dosage you have to go to injections. > I'm currently at 15 mg per week...I still take it orally... all in one shot, not spread out over the 36 hours like some people do...my side effects are less this way.. Haven't tried injections yet, but from the posts I've been reading seems like it may be worth trying! Christie (The American in Taiwan) _________________________________________________________________________ Get Your Private, Free E-mail from MSN Hotmail at http://www.hotmail.com. Share information about yourself, create your own public profile at http://profiles.msn.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 26, 2000 Report Share Posted September 26, 2000 I have a question, I was on MTX and had substantial hair loss. They took me off it and switched me to Arva (which I just started last night)--has anyone had any hair loss problems with it? Rae Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 15, 2003 Report Share Posted December 15, 2003 thank you for your reply. my hubby is taking 1 x 10mg MTX a week. he has to have blood tests every month and will be reducing the cortisone to 1 x 5mg tablet morning and night on january 1st. he has bone erosion in fingers of both hands and both feet also the right hip joint. he had been in extreme pain before being diagnosed to the point wher he couldnt walk and was crawling!!!!!!!!!!!!!!!!! regards ruby _________________________________________________________________ Get less junk mail with ninemsn Premium. Click here http://ninemsn.com.au/premium/landing.asp Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2004 Report Share Posted September 22, 2004 to setagayadama I live in the uk and have pa and my dose of mtx is 25mg --------------------------------- ALL-NEW Messenger - all new features - even more fun! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 23, 2004 Report Share Posted September 23, 2004 I'm at 20 mg per week and I have had good results so far. My problem is confined to inflammation in my hands, stiff and swollen fingers and pain. It takes a few months for MTX to get to full strength. Until this month(I started at 7.5 mg 6 months ago)I have had usually one or two flares per month, so the doctor is recommending that I start a biologic, but I have been feeling better, so I may wait on the biologic and try going to 25 mg per week, which I think is the max. I assume that I will eventually go to the biologic, since the disease has progressively gotten worse over the last 5 years or so. > I was curious as to what dosage of metho everyone was taking? And at what > dosage you have to go to injections. It seems that my rhuemy has to increase > my dosage about every six moths as the effectiveness starts to wear off. Any > input would be helpful. > > > in St. Louis, MO Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 27, 2004 Report Share Posted September 27, 2004 I have a choice of Enbrel or Remicade which as far as I can determine are about equally effective. The Remicade to me is more convenient since it is required only once every two months. It turns out it is much less expensive since my insurance will only pay 70% for Enbrel and they will pay 90% for Remicade. Even though the cost of the Remicade is much higher per dose. I think that the Enbrel copay would be $400 a month or $4800 per year. Remicade copay was $150 per infusion but only 6 per year for $900 total per year. I may try the 25 mg MTX before I go to the biologic, since I have had no flares recently. > Hi, I am on 25 mg of MTX and last time I spoke to my Rheumy nurse she said the Consultant might decide to put me on the injections as these may prove more effective than the tablets. I can tolerate the 25mg of MTX ok, though have had a few stomach problems lately (not sure if related to meds). > What is the biologic? > Thanks > (UK) > > > > I'm at 20 mg per week and I have had good results so far. My problem > is confined to inflammation in my hands, stiff and swollen fingers > and pain. It takes a few months for MTX to get to full strength. > Until this > month(I started at 7.5 mg 6 months ago)I have had usually one or two > flares per month, so the doctor is recommending that I start a > biologic, but I have been feeling better, so I may wait on the > biologic and try going to 25 mg per week, which I think is the max. I > assume that I will eventually go to the biologic, since the disease > has progressively gotten worse over the last 5 years or so. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 29, 2005 Report Share Posted January 29, 2005 > Hi , > I read you talking to others about the Methotrexate. I was on it about two months back but only for about two months. > Well the Doctor did not tell me the right way to take it. I took it once a day instead of once a week!!!!! This is a good reminder to all of us to read the pharmacy literature that comes with any new prescription drugs. Doctors can forget to convey important information; the sheet of paper stapled to the RX bag is an important safety feature. Sierra Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 29, 2005 Report Share Posted January 29, 2005 > Hi , > I read you talking to others about the Methotrexate. I was on it about two months back but only for about two months. > Well the Doctor did not tell me the right way to take it. I took it once a day instead of once a week!!!!! This is a good reminder to all of us to read the pharmacy literature that comes with any new prescription drugs. Doctors can forget to convey important information; the sheet of paper stapled to the RX bag is an important safety feature. Sierra Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 18, 2009 Report Share Posted June 18, 2009 Someone said 20 mg is the max dosage, not so, typically it is 25 mg. I am on 25 mg injectible weekly. ----- Original Message -----From: helen flatau <hlflatau@...>Date: Wednesday, June 17, 2009 20:11Subject: MTX and yummy to mosquitoesRheumatoid Arthritis > I have not had any significant rash while on MTX, but have > noticed the mosquito problem. I am one of those tasty people > anyway, so have used a tablet of brewers yeast each day to make > me less yummy. Perhaps I should up my yeast tablets. They > usually work for me, cause no significant side effects, and are > cheap and easy to take. > I do know that just brewers yeast doesn't work for everyone, so > no guarantee implied.> Still, the simple things are the ones I try first.> Blood pressure medicines and many antibiotics have the same > problem in sunshine. We have had so much rain here around St. > Louis, that until today, I almost forgot what sunshine looked > like! And all that rain increases the mosquito population. > Seems hard to get a break!> Keep trying to make life simple.> > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 25, 2009 Report Share Posted June 25, 2009 I'm glad to read of others taking higher doses of mtx. I started out taking 6 pills weekly. Don't remember the strength but as then was switched to the injectible. I was injecting .6, then .8 and now today my dr. suggested switching to 25mg. I dont understand the conversion to know what my .8 is in relation to the 25mg but I know she's increasing me again. I hate to take a really big dose........ Your thoughts? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 25, 2009 Report Share Posted June 25, 2009 Thank you for explaining that. I was afraid I was increasing to a much larger dose. Thanks --- In Rheumatoid Arthritis , " Harold Van Tuyl " <hvantuyl@...> wrote: > > The standard pill size is 2.5 mg and each 0.1 cc is equivalent to one pill. > Your 0.8 cc is 20 mg and you will be taking 1 cc to get 25 mg. This is > still a very low dose compared to what is used in chemotherapy, but it is > about the tops for treatment of RA. I hope it works well for you. God > bless. > > > > From: Rheumatoid Arthritis > [mailto:Rheumatoid Arthritis ] On Behalf Of > i_live_in_slippers > Sent: Wednesday, June 24, 2009 5:01 PM > Rheumatoid Arthritis > Subject: Re: MTX dosage > > > > > > > > > I'm glad to read of others taking higher doses of mtx. I started out taking > 6 pills weekly. Don't remember the strength but as then was switched to the > injectible. I was injecting .6, then .8 and now today my dr. suggested > switching to 25mg. I dont understand the conversion to know what my .8 is in > relation to the 25mg but I know she's increasing me again. I hate to take a > really big dose........ > > Your thoughts? > Quote Link to comment Share on other sites More sharing options...
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