Gardasil: Polysorbate 80 and Histidine, a marriage of disaster

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http://snipurl.com/3qvsd  [www_renewamerica_us] August 30, 2008Polysorbate 80 and Histidine, a marriage of disasterBy A. JanakDo you know how it is when you have a gut feeling that just won't quit? It is like the itch you just cannot scratch that gets worse with time. It is very annoying. Well, I was finally able to scratch that itch and all my efforts have finally paid off.I have been researching Polysorbate 80 for some time now because I had a gut feeling that there is something to this chemical. I have been doing the same for Histidine because Gardasil is the first vaccine that is using this chemical. I knew that the addition of Histidine had something to do with what we are seeing with Gardasil. Here are my findings.The Polysorbate 80 that is used in Gardasil is a product of Croda Chemicals, Inc. This information I received from a reliable source. The product names are Crills and Crillets. Here is a description of the product. Polysorbate 80 is listed as Crillet 4 Super a clear yellow liquid, (oil in water) O/W emulsifier and dispersant often used in conjunction with the appropriate Crill. Good solubilising properties, recommended in systems with unsaturated lipid components such as oleyl alcohol and vegetable triglyceridesSorbitan esters and their ethoxylatesCrills and Crillets are a range of mild nonionic surfactants providing formulating benefits in a number of personal care applications. Entirely vegetable-derived, Croda's Crills and Crillets have long-standing food and pharmacopoeia approvals and a safe history of use in cosmetic products.Properties and functionsCrillets (Polysorbates) are excellent O/W emulsifiers, solubilisers, wetting agents and dispersants. In emulsion systems they are commonly used in combination with the corresponding Crill. Manipulation of the Crill/Crillet ratio produces emulsifying systems of various HLB (hydrophilic-lipophilic balance) values, allowing the emulsification of many cosmetic ingredients.Health and safetyThe Crills and Crillets are well-established raw materials used in a variety of applications. Certain sorbitan esters are accepted as food additives in Europe. Sorbitan esters are included in the FDA Inactive Ingredients guide. Polysorbates 60 and 80 are GRAS listed. (Generally recognized as safe.)http://www.chservice.ru/download/Crills%20and%20Crillets.pdfI found all this to be very interesting in the development of a vaccine. The reason being, that if you check out the Croda's website you will find and Crill and Crillet are mainly used for personal items and cosmetics. I understand that it is also mentioned that it can be used in a variety of applications but I would think that they would mention vaccines or pharmaceutical uses as well. But that is neither here nor there.What I want to bring to your attention is the fact that Polysorbate 80 is a surfactant. This is very important to remember.sur•fac•tant (sər-făk'tənt, sûr'făk'-) n. A surface-active substance. A substance composed of lipoprotein that is secreted by the alveolar cells of the lung and serves to maintain the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. EtymologyThe term surfactant is a blend of "surface active agent." Surfactants are usually organic compounds that are amphiphilic, meaning they contain both hydrophobic groups (their "tails") and hydrophilic groups (their "heads"). Therefore, they are soluble in both organic solvents and water. The term surfactant was coined by Antara Products in 1950http://www.answers.com/topic/surfactantMy source also explained to me in layman's language what all this means so I am going to impart that information to you. What this does is helps to suspend chemicals or materials evenly in the product that it is being used. In regards to a vaccine this helps to keep all the chemicals and virus like particles evenly distributed. This way one syringe will not have more chemicals and another will not have more virus like particles. You have more uniformity in the vaccine which is very important.Another thing that I want to mention is that Polysorbate 80 is used in other products, such as Epoetin alpha (Eprex ®) and Darbopoetin alpha (Aranesp ®), which help stimulate the production of red blood cells in people suffering from anemia caused by cancer treatment.Now let me bring to you some information about Histidine. (I do not endorse the product on this website.) http://www.cfsn.com/histidine.htmlI was looking for a good explanation of Histidine. Most of the websites that I found were too technical and hard to understand. The above website has an easy to understand definition and that is the only reason that I am using it.L-histidine* is an essential amino acid that cannot be formed by other nutrients, and must be in the diet to be available to the body.Most often recognized as a precursor to the allergy symptom producing hormone histamine, both histidine and histamine have essential roles in the body beyond tormenting allergy sufferers.Histamine is well known for its role in stimulating the inflammatory response of skin and mucous membranes such as those found in the nose — this action is essential in the protection of these barriers during infection.Histamine also stimulates the secretion of the digestive enzyme gastrin. Without adequate histamine production healthy digestion can become impaired. Without adequate L-histidine stores, the body cannot maintain adequate histamine levels.Less well known is that L-histidine is required by the body to regulate and utilize essential trace minerals such as copper, zinc, iron, manganese and molybdenum.The addition of L-histidine in the vaccine Gardasil I believe was a bad idea. Here are my thoughts. You have girls that are suffering after receiving this vaccine and some of the symptoms are nausea, vomiting and irritable bowel. Without adequate histamine production healthy digestion can become impaired. This is the first clue in the puzzle that is besieging these families and doctors that are trying to deal with this new epidemic.Another finding in the girls is that when a hair sample is tested they are finding high levels of metals present. Less well known is that L-histidine is required by the body to regulate and utilize essential trace minerals... Some of the girl's symptoms are typical of metal poisoning such as: nausea, vomiting, diarrhea, stomach pain, headache, sweating... http://www.healthatoz.com/healthatoz/Atoz/common/standard/transform.jsp?requestURI=/healthatoz/Atoz/ency/heavy_metal_poisoning.jsp Use this site for a full description of Heavy Metal Poisoning.There is another thing that is predominate with the girls is joint pain. I have found that low levels of histidine have been found in patients with rheumatoid arthritis.A study of sera from 285 patients with definite or classical rheumatoid arthritis (including 37 patients receiving no anti-inflammatory drugs) and sera from 67 healthy subjects has confirmed 10 published reports of a statistically significant decreased blood histidine concentration in patients with rheumatoid arthritis.http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=301869So what is happening here? It is my opinion that low levels of histidine could be part of the overall problem that the girls are experiencing. Now my question to the medical research community is what could have caused this drop in histidine levels to cause all these problems?I have my theory and that is that the immune response that was produced by the vaccine along with the infusion of histidine produced an unexpected reaction in all the girls that have a family history of allergies.What happened is that because of this history it stands to reason that these girls already had a higher than normal level of histidine/histamine to begin with. Now we have just added more histidine into their systems therefore overloading and creating a dangerous situation. The immune system now has to deal with the dangerous levels of histidine along with the virus like particles and aluminum. Now we have a programmed immune response to the histidine and the immune system is going to attack it.Another thing that L-histidine does is that it can pass through the placental wall to the fetus. This could be the direct cause to the spontaneous miscarriage and birth defects in some of the babies. Here is the MSDS (material safety data sheet) quote. Section 11: Toxicological Information, Special Remarks on Chronic Effects on Humans: Passes through the placental barrier in humans. http://www.sciencelab.com/xMSDS-L_Histidine-9927189Now this is where it gets interesting. I am going to tell you about the marriage of Polysobate 80 a surfactant and histidine. This is one marriage that was doomed to failure from the start. Let me show you what I just found out a few days ago.http://www.anesthesiology.org/pt/re/anes/fulltext.00000542-200401000-00015.htm;jsessionid=LzQLy51JWy1VS2X8GtvFWGpKYnTHQ5gx9XxxB0jXv32cXFZPp37M!2126095447!181195629!8091!-1The title of this report is Surfactants Attenuate Gas Embolism-induced Thrombin Production.[1]Background: There are no pharmacologic strategies to prevent embolism bubble-induced blood clot formation. The authors conducted experiments to measure thrombin production in sheared whole blood in the presence and absence of bubbles and three surface-active compounds.[cont'd on site] =====In accordance with Title 17 U.S.C. Section 107, this material is distributed without profit to those who have expressed a prior interest in receiving the included information for research and educational purposes.