Disrupted neural synchronization in toddlers with autism

[Guest guest]

Disrupted neural

synchronization in toddlers with autism.

Dinstein I, Pierce K, Eyler L, Solso S, Malach R, Behrmann

M, Courchesne E.

Neuron. 2011 Jun 23;70(6):1218-25.

Autism is often described as a disorder of neural synchronization.

However, it is unknown how early in development synchronization

abnormalities emerge and whether they are related to the development of

early autistic behavioral symptoms. Here, we show that disrupted

synchronization is evident in the spontaneous cortical activity of

naturally sleeping toddlers with autism, but not in toddlers with

language delay or typical development. Toddlers with autism exhibited

significantly weaker interhemispheric synchronization (i.e., weak

" functional connectivity " across the two hemispheres) in

putative language areas. The strength of synchronization was positively

correlated with verbal ability and negatively correlated with autism

severity, and it enabled identification of the majority of autistic

toddlers (72%) with high accuracy (84%). Disrupted cortical

synchronization, therefore, appears to be a notable characteristic of

autism neurophysiology that is evident at very early stages of autism

development.

Sheri Nakken, former R.N., MA, Hahnemannian

Homeopath

Vaccination Information & Choice Network, Washington State, USA

Vaccines -

http://vaccinationdangers.wordpress.com/ Homeopathy

http://homeopathycures.wordpress.com

Vaccine Dangers, Childhood Disease Classes & Homeopathy

Online/email courses - next classes start April 22

[Guest guest]

Disrupted neural

synchronization in toddlers with autism.

Dinstein I, Pierce K, Eyler L, Solso S, Malach R, Behrmann

M, Courchesne E.

Neuron. 2011 Jun 23;70(6):1218-25.

Autism is often described as a disorder of neural synchronization.

However, it is unknown how early in development synchronization

abnormalities emerge and whether they are related to the development of

early autistic behavioral symptoms. Here, we show that disrupted

synchronization is evident in the spontaneous cortical activity of

naturally sleeping toddlers with autism, but not in toddlers with

language delay or typical development. Toddlers with autism exhibited

significantly weaker interhemispheric synchronization (i.e., weak

" functional connectivity " across the two hemispheres) in

putative language areas. The strength of synchronization was positively

correlated with verbal ability and negatively correlated with autism

severity, and it enabled identification of the majority of autistic

toddlers (72%) with high accuracy (84%). Disrupted cortical

synchronization, therefore, appears to be a notable characteristic of

autism neurophysiology that is evident at very early stages of autism

development.

Sheri Nakken, former R.N., MA, Hahnemannian

Homeopath

Vaccination Information & Choice Network, Washington State, USA

Vaccines -

http://vaccinationdangers.wordpress.com/ Homeopathy

http://homeopathycures.wordpress.com

Vaccine Dangers, Childhood Disease Classes & Homeopathy

Online/email courses - next classes start April 22