The underestimated risk of hepatitis A and hepatitis B: benefits of an accelerated vaccination sched

[Guest guest]

International Journal of Infectious Diseases

Volume 12, Issue 1, January 2008, Pages 3-11

Review

The underestimated risk of hepatitis A and hepatitis B: benefits of an

accelerated vaccination schedule

Jay S. Keystonea, , and Jody H. Hersheyb

aDivision of Infectious Disease, Department of Medicine, Tropical Disease Unit,

Toronto General Hospital, University of Toronto, Toronto, Ontario M5G 2C4,

Canada

bFamily and Preventive Medicine, Via Virginia College of Osteopathic

Medicine, and New River Health District, Christiansburg, Virginia, USA

Received 9 February 2007; revised 23 April 2007; accepted 24 April 2007.

Corresponding Editor: Cameron, Ottawa, Canada. Available online 20 July

2007.

Summary

Hepatitis A virus (HAV) and hepatitis B virus (HBV) are vaccine-preventable.

Current recommendations advocate vaccination of non-immune adults at risk of

exposure, including travelers to HAV or HBV endemic areas, individuals with high

risk of contracting a sexually transmitted infection, and some correctional

facility inmates. We review the use of an accelerated schedule to administer the

combination hepatitis A and hepatitis B vaccine (Twinrix®). Administering three

doses over three weeks and a fourth at 12 months provides rapid initial

protection of most individuals for whom the standard 6-month vaccination

schedule would not be suitable, including last-minute travelers and short-term

correctional facility inmates. Furthermore, we consider the role of a universal

vaccination strategy in preventing the spread of HAV and HBV.

FREE FULL

TEXT:http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B7CPT-4P7FD3K-2 & _u\

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_________________________________________________________________

i’m is proud to present Cause Effect, a series about real people making a

difference.

http://im.live.com/Messenger/IM/MTV/?source=text_Cause_Effect

[Guest guest]

International Journal of Infectious Diseases

Volume 12, Issue 1, January 2008, Pages 3-11

Review

The underestimated risk of hepatitis A and hepatitis B: benefits of an

accelerated vaccination schedule

Jay S. Keystonea, , and Jody H. Hersheyb

aDivision of Infectious Disease, Department of Medicine, Tropical Disease Unit,

Toronto General Hospital, University of Toronto, Toronto, Ontario M5G 2C4,

Canada

bFamily and Preventive Medicine, Via Virginia College of Osteopathic

Medicine, and New River Health District, Christiansburg, Virginia, USA

Received 9 February 2007; revised 23 April 2007; accepted 24 April 2007.

Corresponding Editor: Cameron, Ottawa, Canada. Available online 20 July

2007.

Summary

Hepatitis A virus (HAV) and hepatitis B virus (HBV) are vaccine-preventable.

Current recommendations advocate vaccination of non-immune adults at risk of

exposure, including travelers to HAV or HBV endemic areas, individuals with high

risk of contracting a sexually transmitted infection, and some correctional

facility inmates. We review the use of an accelerated schedule to administer the

combination hepatitis A and hepatitis B vaccine (Twinrix®). Administering three

doses over three weeks and a fourth at 12 months provides rapid initial

protection of most individuals for whom the standard 6-month vaccination

schedule would not be suitable, including last-minute travelers and short-term

correctional facility inmates. Furthermore, we consider the role of a universal

vaccination strategy in preventing the spread of HAV and HBV.

FREE FULL

TEXT:http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B7CPT-4P7FD3K-2 & _u\

ser=10 & _coverDate=01%2F31%2F2008 & _rdoc=3 & _fmt=full & _orig=browse & _srch=doc-info(%\

23toc%2317975%232008%23999879998%23677630%23FLA%23display%23Volume) & _cdi=17975 & _\

sort=d & _docanchor= & _ct=26 & _acct=C000050221 & _version=1 & _urlVersion=0 & _userid=10 & m\

d5=47ed439839b44c23a86ca1c455030430

_________________________________________________________________

i’m is proud to present Cause Effect, a series about real people making a

difference.

http://im.live.com/Messenger/IM/MTV/?source=text_Cause_Effect