An outbreak of hepatitis B virus infection among methamphetamine injectors: the

[Guest guest]

An outbreak of hepatitis B virus infection among methamphetamine injectors:

the role of sharing injection drug equipment

Authors: Vogt, Tara M.; Perz, ph F.1; Van Houten, Clayton K.2;

Harrington, 3; Hansuld, Tia3; Bialek, R.1; ston,

2; Bratlie, 1; , Ian T.1

Source: Addiction, Volume 101, Number 5, May 2006, pp. 726-730(5)

Publisher: Blackwell Publishing

Abstract:

Aim & #8195;

To identify risk factors for acute hepatitis B virus (HBV) infection among

Wyoming methamphetamine injectors. Design & #8195;

A case–control study conducted in the setting of an outbreak. Setting & #8195;

A county in central Wyoming, United States. Participants & #8195;

Cases were identified through surveillance and contact tracing and were

defined as Natrona County, Wyoming, residents who were either symptomatic or

confirmed serologically to be acutely infected with HBV during

January–August, 2003. Controls were susceptible to HBV infection. All

participants identified themselves as methamphetamine injectors.

Measurements & #8195;

Participants were administered a survey that inquired about risk factors for

HBV infection, including drug use practices and sexual behaviors. Controls

were also tested serologically for acute HBV infection. Findings & #8195;

Among the 18 case-patients and 49 controls who participated in the study,

sharing water used to prepare injections and/or rinse syringes was

associated with HBV infection (94% of case-participants versus 44% of

controls; OR & #8201;= & #8201;21.9, 95% CI: 2.7, 177.8), as was sharing cotton

filters (89% of case-participants versus 52% of controls;

OR & #8201;= & #8201;7.4, 95% CI: 1.5, 35.6); sharing syringes was not

statistically associated. In logistic regression models adjusted for age,

sex, and interview site, sharing rinse water and sharing cotton remained

statistically associated. Conclusions & #8195;

Methamphetamine use has become increasingly prevalent in the United States.

Our findings highlight the need for awareness of risks associated with

injection drug use and sharing behaviors. Enhanced hepatitis B vaccination

programs and educational campaigns that target methamphetamine injectors

specifically, including those living in rural areas, should be developed and

implemented.

Keywords: Disease outbreaks; hepatitis B; intravenous; methamphetamine;

substance abuse; vaccination

Document Type: Research article

DOI: 10.1111/j.1360-0443.2006.01407.x

Affiliations: 1: Division of Viral Hepatitis, Centers for Disease Control

and Prevention, Atlanta, Georgia, USA, 2: Preventive Health and Safety

Division, Wyoming Department of Health, Cheyenne, Wyoming, USA and 3:

Casper-Natrona County Health Department, Casper, Wyoming, USA

_________________________________________________________________

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[Guest guest]

An outbreak of hepatitis B virus infection among methamphetamine injectors:

the role of sharing injection drug equipment

Authors: Vogt, Tara M.; Perz, ph F.1; Van Houten, Clayton K.2;

Harrington, 3; Hansuld, Tia3; Bialek, R.1; ston,

2; Bratlie, 1; , Ian T.1

Source: Addiction, Volume 101, Number 5, May 2006, pp. 726-730(5)

Publisher: Blackwell Publishing

Abstract:

Aim & #8195;

To identify risk factors for acute hepatitis B virus (HBV) infection among

Wyoming methamphetamine injectors. Design & #8195;

A case–control study conducted in the setting of an outbreak. Setting & #8195;

A county in central Wyoming, United States. Participants & #8195;

Cases were identified through surveillance and contact tracing and were

defined as Natrona County, Wyoming, residents who were either symptomatic or

confirmed serologically to be acutely infected with HBV during

January–August, 2003. Controls were susceptible to HBV infection. All

participants identified themselves as methamphetamine injectors.

Measurements & #8195;

Participants were administered a survey that inquired about risk factors for

HBV infection, including drug use practices and sexual behaviors. Controls

were also tested serologically for acute HBV infection. Findings & #8195;

Among the 18 case-patients and 49 controls who participated in the study,

sharing water used to prepare injections and/or rinse syringes was

associated with HBV infection (94% of case-participants versus 44% of

controls; OR & #8201;= & #8201;21.9, 95% CI: 2.7, 177.8), as was sharing cotton

filters (89% of case-participants versus 52% of controls;

OR & #8201;= & #8201;7.4, 95% CI: 1.5, 35.6); sharing syringes was not

statistically associated. In logistic regression models adjusted for age,

sex, and interview site, sharing rinse water and sharing cotton remained

statistically associated. Conclusions & #8195;

Methamphetamine use has become increasingly prevalent in the United States.

Our findings highlight the need for awareness of risks associated with

injection drug use and sharing behaviors. Enhanced hepatitis B vaccination

programs and educational campaigns that target methamphetamine injectors

specifically, including those living in rural areas, should be developed and

implemented.

Keywords: Disease outbreaks; hepatitis B; intravenous; methamphetamine;

substance abuse; vaccination

Document Type: Research article

DOI: 10.1111/j.1360-0443.2006.01407.x

Affiliations: 1: Division of Viral Hepatitis, Centers for Disease Control

and Prevention, Atlanta, Georgia, USA, 2: Preventive Health and Safety

Division, Wyoming Department of Health, Cheyenne, Wyoming, USA and 3:

Casper-Natrona County Health Department, Casper, Wyoming, USA

_________________________________________________________________

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http://search.msn.click-url.com/go/onm00200636ave/direct/01/