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RE: Lactic Acid

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****the liver actually converts glucose TO lactic acid, IIRC.

-------------->oops! did i write that? i think it's the opposite. or maybe

both...at least i recall reading that the lactic acid that tumor metabolism

produces is transported to the liver and converted to glucose and it becomes

a catch 22 cycle...glucose to lactic acid, lactic acid to glucose (if my

memory's not completely failing me...). OK, someone who *really* knows what

they're talking about, come to my aid please!

Suze Fisher

Web Design & Development

http://members.bellatlantic.net/~vze3shjg/

mailto:s.fisher22@...

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At 07:36 AM 7/25/2002 -0400, you wrote:

>*****heidi, i know that's the case with alcohol, but are you sure about

>glucose being absorbed directly from the stomach?? that's the first i'm

>hearing this. i've reaad about 3 books on digestion so far and don't recall

>that being mentioned anywhere. maybe they *did* mention it, and i just

>didn't retain it. typically, unless we're eating straight glucose (does

>anyone do that?), the glucose is a product of the breakdown of more complex

>starches in the small intestine, as i know you know. starches do not get

>digested in the stomach, except to the extent that HCl breaks them down a

>bit, but they are digested in earnest, in the small intestine.

I think I heard it in Physiology class (we got into digestion alot). Starches

are broken down quite a bit with saliva, and (or so I was taught) they begin

to enter the bloodstream as soon as you swallow. Which makes sense, because

your stomach doesn't empty all that fast and when you eat candy, you start

getting a rush pretty quick.

I don't think anyone makes a habit of drinking straight glucose, but I did

for an 8-hour blood sugar test. It seems to hit the bloodstream darn fast!

> i can't think

>of any food that would be pure glucose...that would be absorbed directly

>from the stomach. do body builders consume it straight or something???

No, the body builders consume MCT, which supposedly goes stright

to the live through the portal vein.

> >>>>>If your body normally handles lactic acid in the liver too, then I'd

>assume the same thing happens -- it just gets shuffled to the liver.

>

>****the liver actually converts glucose TO lactic acid, IIRC. I think that's

>a very different thing than transporting lactic acid from the digestive

>tract to the liver. I'd really like to know what happens to the lactic acid

>that us WAP/NT types are consuming in our lacto-fermented foods. what

>happens to it once we eat/drink it?

Me too! But it DOES sound like the liver just turns it into glucose:

Once sufficient oxygen is restored, the lactic acid produced via anaerobic

glycolysis can be utilized for energy or reconverted into glucose by the

liver and other tissues (a process known as oxidation). This brings us full

circle, and the rest of the metabolic functions as quoted earlier from

have been met. This process also applies to the world of exercise.

http://www.uoregon.edu/~iishp/Vannat.html

>

Heidi

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Suze-

>I'd really like to know what happens to the lactic acid

>that us WAP/NT types are consuming in our lacto-fermented foods. what

>happens to it once we eat/drink it?

That's the burning question, isn't it. <g>

-

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> >>>>>--Lactate and lactic acid are differentiated in the Merck

Manual

> and in Dorland's Medical dictionary. There are different forms of

> lactic acid as well (Dand L). I was just perusing the general

biochem

> book and metabolism is COMPLICATED.

>

> --------->Dennis, is your biochem book novice, intermediate, or

advanced?

> I'm looking for a good one. i can handle intermediate (i think) but

advanced

> would be out of my league at this time. Can you tell me the name of

it, and

> do you recommend it?

>

<><><<><Suze this book is entitled OUTLINES OF BIOCHEMISTRY, third

edition by E. Conn and P.K. Stumpf published 1972. I used it for

general biochemistry class in 1977. It's ok (I'd recommend it) 'cause

I'm familiar with it but I'm sure you can get more info over the

internet since you know how to access it. Otherwise I'd recommend

getting a used book at a university or a used book bookstore.

Anyway this book is simply academic biochem written about what was

known 30+ years ago. I'm sure a more recent edition will have more

info (to study)! As far as it's accuracy I have no clue cause I would

have to know a lot more biochem to do that.All biochem at the

university, IMO is intermediate and advanced. A student usually begins

biochem classes after taking 10 or so hours of chemistry. That

doesn't mean it has to be done that way. And the two references I

mentioned above are helpful. I'm sure there's more written more

recently that would be helpful as well. Another reference book I

discovered at this place of employ is great and is: Hackh's Chemical

Dictionary, by Julius Grant, published in 1944 by Mcgraw-Hill book

Company, Inc. A newer one could be even better. Dennis

> Suze Fisher

> Web Design & Development

> http://members.bellatlantic.net/~vze3shjg/

> mailto:s.fisher22@v...

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> > >Lactic acid is the negative lactate molecule (ion) plus the

positive

> > >hydrogen ion. In a solution, how much of the lactic acid

molecule is

> > >dissociated into lactate and H+ ions will depend on the pH and

the

> > >amount of the lactic acid.

> > >Same as for acetic acid and acetate or glutamic acid and

glutamate.

> > >(Lactate or acetate could also be in a salt with sodium or

potassium

> > >or calcium isntead of in an acid with hydrogen.)

> >

> > Seems like I remember something along those lines from chem 101 --

you mix

> an

> > acid and a base and you get a salt. So if you mixed kefir with

baking soda

> > you'd

> > get some lactate?

>

> Specifically, sodium lactate.

<><<<><><> When you get to physical chem 401? it's gets messier for

me. The reaction would reach equilibrium and you'd have residual

lactic acid provided you kept the pH below 7 right? and then you have

to consider kinetics ie reaction rates, temperatures, acidity? Lactic

acid is a weak acid so it disassociates much less meaning the lactic

acid molecule " prefers " staying intact rather than being ionized as H+

and lactate. IS there any truth to that statement?

How does water disassociate anyway? anyone remember that? Dennis

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