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HBV Infection Decreases Risk of Liver Metastasis in Colorectal Cancer Patients

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http://www.sciencedaily.com/releases/2011/03/110308101321.htm

HBV Infection Decreases Risk of Liver Metastasis in Colorectal Cancer Patients

ScienceDaily (Mar. 8, 2011) — Colorectal cancer (CRC) is the second leading

cause of cancer-related deaths in Western countries. Metastatic liver disease

more frequently develops metachronous metastasis following treatment of CRC. It

was reported that hepatitis B virus (HBV) infection finally reduces the risk of

intrahepatic metastasis in hepatocellular carcinoma (HCC) patients with a higher

survival rate and therefore can be considered an important prognostic factor for

HCC patients. Rare reports are available on the relation between HBV infection

and hepatic metastasis of CRC.

A research article to be published on February 14, 2011 in the World Journal of

Gastroenterology addresses this question. The authors designed a cohort study to

observe the relation between HBV infection and liver metastasis of CRC.

The results showed a decrease in the percentage of metastases in the Hepatitis B

virus infected group (14.2%) with respect to the control group (28.2%). In

contrast, the number of patients that developed extrahepatic metastases was

significantly higher than the control group, without any significant difference

in the overall survival rate.

Finally, the authors suggested that HBV infection in colorectal cancer patients

could be used as a prognostic factor in terms of hepatic metastasis formation.

(full report to follow in new email)

--------------------------------------------------------------------------------

Story Source:

The above story is reprinted (with editorial adaptations by ScienceDaily staff)

from materials provided by World Journal of Gastroenterology, via EurekAlert!, a

service of AAAS.

--------------------------------------------------------------------------------

Journal Reference:

1.Qiu HB, Zhang LY, Zeng ZL, Wang ZQ, Luo HY, Keshari RP, Zhou ZW, Xu RH. HBV

infection decreases risk of liver metastasis in patients with colorectal cancer:

A cohort study. World Journal of Gastroenterology, 2011; 17 (6): 804 DOI:

10.3748/wjg.v17.i6.804

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http://www.sciencedaily.com/releases/2011/03/110308101321.htm

HBV Infection Decreases Risk of Liver Metastasis in Colorectal Cancer Patients

ScienceDaily (Mar. 8, 2011) — Colorectal cancer (CRC) is the second leading

cause of cancer-related deaths in Western countries. Metastatic liver disease

more frequently develops metachronous metastasis following treatment of CRC. It

was reported that hepatitis B virus (HBV) infection finally reduces the risk of

intrahepatic metastasis in hepatocellular carcinoma (HCC) patients with a higher

survival rate and therefore can be considered an important prognostic factor for

HCC patients. Rare reports are available on the relation between HBV infection

and hepatic metastasis of CRC.

A research article to be published on February 14, 2011 in the World Journal of

Gastroenterology addresses this question. The authors designed a cohort study to

observe the relation between HBV infection and liver metastasis of CRC.

The results showed a decrease in the percentage of metastases in the Hepatitis B

virus infected group (14.2%) with respect to the control group (28.2%). In

contrast, the number of patients that developed extrahepatic metastases was

significantly higher than the control group, without any significant difference

in the overall survival rate.

Finally, the authors suggested that HBV infection in colorectal cancer patients

could be used as a prognostic factor in terms of hepatic metastasis formation.

(full report to follow in new email)

--------------------------------------------------------------------------------

Story Source:

The above story is reprinted (with editorial adaptations by ScienceDaily staff)

from materials provided by World Journal of Gastroenterology, via EurekAlert!, a

service of AAAS.

--------------------------------------------------------------------------------

Journal Reference:

1.Qiu HB, Zhang LY, Zeng ZL, Wang ZQ, Luo HY, Keshari RP, Zhou ZW, Xu RH. HBV

infection decreases risk of liver metastasis in patients with colorectal cancer:

A cohort study. World Journal of Gastroenterology, 2011; 17 (6): 804 DOI:

10.3748/wjg.v17.i6.804

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