Treatment of chronic hepatitis B: Recommendations from an Italian workshop

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Digestive and Liver Disease

Volume 40, Issue 8, August 2008, Pages 603-617

Progress Report

Treatment of chronic hepatitis B: Recommendations from an Italian workshop

G. Carosia, , and M. Rizzettob

aDepartment of Infectious and Tropical Diseases, University of Brescia, AO

Spedali Civili, Brescia, Italy

bDepartment of Gastroenterology, University of Turin, Turin, Italy

Received 13 February 2008; accepted 4 March 2008. Available online 22 May

2008.

References and further reading may be available for this article. To view

references and further reading you must purchase this article.

Abstract

The changing scenario of hepatitis B virus therapy has encouraged the

organisation of a workshop, endorsed by three Italian scientific societies,

aimed at defining the current recommendations for hepatitis B virus treatment.

Liver histology and stage of disease remain fundamental for treatment decisions;

interferon and nucleoside/nucleotide analogues-based therapy represent different

strategies for different phases of the hepatitis B virus disease. The

recommendations defined: new and lower cut-off of hepatitis B virus–DNA for

eligibility to therapy according to disease stage, how to optimise the use of

nucleoside/nucleotide analogues and to individualise the monitoring of response

and what to do with treatment failures. Specific recommendations have also been

given for cirrhosis patients, those immune suppressed and co-infected with HIV

and other hepatitis viruses.

Keywords: Antiviral therapy; Cirrhosis; HBV

_________________________________________________________________

The other season of giving begins 6/24/08. Check out the i’m Talkathon.

http://www.imtalkathon.com?source=TXT_EML_WLH_SeasonOfGiving

[Guest guest]

http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B7582-4SK0C3G-1 & _user=1\

0 & _coverDate=08%2F31%2F2008 & _rdoc=2 & _fmt=high & _orig=browse & _srch=doc-info(%23toc\

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657442c12ad5896e9a5d5401a162dc

Digestive and Liver Disease

Volume 40, Issue 8, August 2008, Pages 603-617

Progress Report

Treatment of chronic hepatitis B: Recommendations from an Italian workshop

G. Carosia, , and M. Rizzettob

aDepartment of Infectious and Tropical Diseases, University of Brescia, AO

Spedali Civili, Brescia, Italy

bDepartment of Gastroenterology, University of Turin, Turin, Italy

Received 13 February 2008; accepted 4 March 2008. Available online 22 May

2008.

References and further reading may be available for this article. To view

references and further reading you must purchase this article.

Abstract

The changing scenario of hepatitis B virus therapy has encouraged the

organisation of a workshop, endorsed by three Italian scientific societies,

aimed at defining the current recommendations for hepatitis B virus treatment.

Liver histology and stage of disease remain fundamental for treatment decisions;

interferon and nucleoside/nucleotide analogues-based therapy represent different

strategies for different phases of the hepatitis B virus disease. The

recommendations defined: new and lower cut-off of hepatitis B virus–DNA for

eligibility to therapy according to disease stage, how to optimise the use of

nucleoside/nucleotide analogues and to individualise the monitoring of response

and what to do with treatment failures. Specific recommendations have also been

given for cirrhosis patients, those immune suppressed and co-infected with HIV

and other hepatitis viruses.

Keywords: Antiviral therapy; Cirrhosis; HBV

_________________________________________________________________

The other season of giving begins 6/24/08. Check out the i’m Talkathon.

http://www.imtalkathon.com?source=TXT_EML_WLH_SeasonOfGiving