Neonatal immunization: where do we stand?

[Guest guest]

no one seems to realize the incredible-ness of our human bodies and

always wanting to interfere

Breastfeed, give good safe pure food and water and mix with love

and..........voila - health without vaccination - never will have health

with vaccination

Sheri

" Hurdles to neonatal vaccination include safety concerns, both

immunological and clinical, demonstration of vaccine efficacy and public

acceptance. "

Neonatal

immunization: where do we stand?

Wood N, Siegrist CA.

Curr Opin Infect Dis. 2011 Jun;24(3):190-5.

Abstract

PURPOSE OF REVIEW: Recognition of the high

burden of disease in early life and advances in the understanding of

neonatal immunology have resulted in renewed interest in maternal and

neonatal vaccination. This article reviews existing information and

recent advances in neonatal human immunization.

RECENT FINDINGS: Recent findings have demonstrated the

neonatal immune system not to be immature but rather specifically adapted

for early postnatal life. This includes the preferential induction of

memory B cell rather than antibody-secreting plasma cells and

polarization of neonatal T-cell responses away from potentially

deleterious T-helper type 1 cytokines. Recent neonatal acellular

pertussis and pneumococcal conjugate vaccine trials have proven that a

birth dose of acellular pertussis and/or pneumococcal vaccine, in limited

samples sizes, are well tolerated and immunogenic; however they have

identified vaccine interference as a critical issue to address.

SUMMARY: Neonatal immunization may be a well tolerated

and effective preventive strategy against early life pathogens. Research

to better understand how neonatal vaccine responses are elicited and to

identify optimal early life adjuvants and formulations may broaden

neonatally vaccine-preventable diseases to pertussis, rotavirus and

possibly influenza, further reducing disease burden in this vulnerable

group. Hurdles to neonatal vaccination include safety concerns, both

immunological and clinical, demonstration of vaccine efficacy and public

acceptance.PMID:

21415741

Sheri Nakken, former R.N., MA, Hahnemannian

Homeopath

Vaccination Information & Choice Network, Washington State, USA

Vaccines -

http://vaccinationdangers.wordpress.com/ Homeopathy

http://homeopathycures.wordpress.com

Vaccine Dangers, Childhood Disease Classes & Homeopathy

Online/email courses - next classes start April 22

[Guest guest]

no one seems to realize the incredible-ness of our human bodies and

always wanting to interfere

Breastfeed, give good safe pure food and water and mix with love

and..........voila - health without vaccination - never will have health

with vaccination

Sheri

" Hurdles to neonatal vaccination include safety concerns, both

immunological and clinical, demonstration of vaccine efficacy and public

acceptance. "

Neonatal

immunization: where do we stand?

Wood N, Siegrist CA.

Curr Opin Infect Dis. 2011 Jun;24(3):190-5.

Abstract

PURPOSE OF REVIEW: Recognition of the high

burden of disease in early life and advances in the understanding of

neonatal immunology have resulted in renewed interest in maternal and

neonatal vaccination. This article reviews existing information and

recent advances in neonatal human immunization.

RECENT FINDINGS: Recent findings have demonstrated the

neonatal immune system not to be immature but rather specifically adapted

for early postnatal life. This includes the preferential induction of

memory B cell rather than antibody-secreting plasma cells and

polarization of neonatal T-cell responses away from potentially

deleterious T-helper type 1 cytokines. Recent neonatal acellular

pertussis and pneumococcal conjugate vaccine trials have proven that a

birth dose of acellular pertussis and/or pneumococcal vaccine, in limited

samples sizes, are well tolerated and immunogenic; however they have

identified vaccine interference as a critical issue to address.

SUMMARY: Neonatal immunization may be a well tolerated

and effective preventive strategy against early life pathogens. Research

to better understand how neonatal vaccine responses are elicited and to

identify optimal early life adjuvants and formulations may broaden

neonatally vaccine-preventable diseases to pertussis, rotavirus and

possibly influenza, further reducing disease burden in this vulnerable

group. Hurdles to neonatal vaccination include safety concerns, both

immunological and clinical, demonstration of vaccine efficacy and public

acceptance.PMID:

21415741

Sheri Nakken, former R.N., MA, Hahnemannian

Homeopath

Vaccination Information & Choice Network, Washington State, USA

Vaccines -

http://vaccinationdangers.wordpress.com/ Homeopathy

http://homeopathycures.wordpress.com

Vaccine Dangers, Childhood Disease Classes & Homeopathy

Online/email courses - next classes start April 22

[Guest guest]

"Recognition of the high burden of disease in early life.."

High burden? What high burden?

Winnie Neonatal immunization: where do we stand?Recipient list suppressed: ;> no one seems to realize the incredible-ness of our human bodies > and > always wanting to interfere> Breastfeed, give good safe pure food and water and mix with love > and..........voila - health without vaccination - never will > have > health with vaccination> Sheri> > "Hurdles to neonatal vaccination include safety concerns, both > immunological and clinical, demonstration of vaccine efficacy > and > public acceptance."> > Neonatal > immunization: > where do we stand?> Wood N, Siegrist CA.> Curr Opin Infect Dis. 2011 Jun;24(3):190-5.> > > > > Abstract> > > > > > PURPOSE OF REVIEW:> > Recognition of the high burden of disease in early life and > advances > in the understanding of neonatal immunology have resulted in > renewed > interest in maternal and neonatal vaccination. This article > reviews > existing information and recent advances in neonatal human > immunization.> > > RECENT FINDINGS:> > Recent findings have demonstrated the neonatal immune system not > to > be immature but rather specifically adapted for early postnatal > life. > This includes the preferential induction of memory B cell rather > than > antibody-secreting plasma cells and polarization of neonatal T-> cell > responses away from potentially deleterious T-helper type 1 > cytokines. Recent neonatal acellular pertussis and pneumococcal > conjugate vaccine trials have proven that a birth dose of > acellular > pertussis and/or pneumococcal vaccine, in limited samples sizes, > are > well tolerated and immunogenic; however they have identified > vaccine > interference as a critical issue to address.> > > > SUMMARY:> > Neonatal immunization may be a well tolerated and effective > preventive strategy against early life pathogens. Research to > better > understand how neonatal vaccine responses are elicited and to > identify optimal early life adjuvants and formulations may > broaden > neonatally vaccine-preventable diseases to pertussis, rotavirus > and > possibly influenza, further reducing disease burden in this > vulnerable group. Hurdles to neonatal vaccination include safety > concerns, both immunological and clinical, demonstration of > vaccine > efficacy and public acceptance.PMID:> 21415741> > > Sheri Nakken, former R.N., MA, Hahnemannian Homeopath> Vaccination Information & Choice Network, Washington State, USA> Vaccines - http://vaccinationdangers.wordpress.com/ Homeopathy > http://homeopathycures.wordpress.com> Vaccine Dangers, Childhood Disease Classes & Homeopathy > Online/email > courses - next classes start April 22>