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Maternal Characteristics and Hospital Policies as Risk Factors for Nonreceipt of Hepatitis B Vaccine in the Newborn Nursery.

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Pediatr Infect Dis J. 2011 Sep 21. [Epub ahead of print]

Maternal Characteristics and Hospital Policies as Risk Factors for Nonreceipt of

Hepatitis B Vaccine in the Newborn Nursery.

Oʼleary ST, C, Duran J.

Source

From the *Department of Pediatrics, University of Colorado Anschutz Medical

Campus, Aurora, CO; †Children's Outcomes Research Program, Children's Hospital

Colorado, Aurora, CO; ‡Disease Control and Environmental Epidemiology

Division, Colorado School of Public Health, Denver, CO; and §Colorado

Department of Public Health and Environment, Denver, CO.

Abstract

BACKGROUND:

A birth dose of hepatitis B vaccine (HBV) is a primary focus of the Advisory

Committee on Immunization Practices' strategy to eliminate transmission of

hepatitis B virus in the United States. We sought to assess the impact of

maternal characteristics and hospital policy on the receipt of a birth dose of

HBV.

METHODS:

A retrospective cohort study was performed using data from the 2008 Colorado

birth registry. Hospital policy was assessed by state health department

personnel. Univariate and multivariate logistic regression analyses were used to

examine the association of maternal characteristics and hospital policy with

nonreceipt of HBV.

RESULTS:

A total of 64,425 infants were identified in the birth cohort, of whom 61.6%

received a birth dose of HBV. Higher maternal education and income were

associated with nonreceipt of HBV (master's degree vs. eighth grade or less:

adjusted odds ratio [OR] = 1.66, 95% confidence interval [CI] = 1.49-1.85;

>$75,000 vs. <$15,000: adjusted OR = 1.21, 95% CI = 1.13-1.30). Lack of a

hospital policy stipulating a universal birth dose strongly predicted nonreceipt

of a birth dose of HBV (policy with no birth dose vs. policy with a birth dose:

adjusted OR = 2.21, 95% CI = 2.13-2.30).

CONCLUSIONS:

Maternal characteristics such as higher education and income are associated with

nonreceipt of the HBV during the perinatal period. To effectively reduce risk of

perinatal hepatitis B transmission, hospitals should stipulate that all infants

are offered HBV and ensure that these policies are implemented and followed.

PMID: 21941215 [PubMed - as supplied by publisher]

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Pediatr Infect Dis J. 2011 Sep 21. [Epub ahead of print]

Maternal Characteristics and Hospital Policies as Risk Factors for Nonreceipt of

Hepatitis B Vaccine in the Newborn Nursery.

Oʼleary ST, C, Duran J.

Source

From the *Department of Pediatrics, University of Colorado Anschutz Medical

Campus, Aurora, CO; †Children's Outcomes Research Program, Children's Hospital

Colorado, Aurora, CO; ‡Disease Control and Environmental Epidemiology

Division, Colorado School of Public Health, Denver, CO; and §Colorado

Department of Public Health and Environment, Denver, CO.

Abstract

BACKGROUND:

A birth dose of hepatitis B vaccine (HBV) is a primary focus of the Advisory

Committee on Immunization Practices' strategy to eliminate transmission of

hepatitis B virus in the United States. We sought to assess the impact of

maternal characteristics and hospital policy on the receipt of a birth dose of

HBV.

METHODS:

A retrospective cohort study was performed using data from the 2008 Colorado

birth registry. Hospital policy was assessed by state health department

personnel. Univariate and multivariate logistic regression analyses were used to

examine the association of maternal characteristics and hospital policy with

nonreceipt of HBV.

RESULTS:

A total of 64,425 infants were identified in the birth cohort, of whom 61.6%

received a birth dose of HBV. Higher maternal education and income were

associated with nonreceipt of HBV (master's degree vs. eighth grade or less:

adjusted odds ratio [OR] = 1.66, 95% confidence interval [CI] = 1.49-1.85;

>$75,000 vs. <$15,000: adjusted OR = 1.21, 95% CI = 1.13-1.30). Lack of a

hospital policy stipulating a universal birth dose strongly predicted nonreceipt

of a birth dose of HBV (policy with no birth dose vs. policy with a birth dose:

adjusted OR = 2.21, 95% CI = 2.13-2.30).

CONCLUSIONS:

Maternal characteristics such as higher education and income are associated with

nonreceipt of the HBV during the perinatal period. To effectively reduce risk of

perinatal hepatitis B transmission, hospitals should stipulate that all infants

are offered HBV and ensure that these policies are implemented and followed.

PMID: 21941215 [PubMed - as supplied by publisher]

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