Chilling impact on vaccine-autism research

[Guest guest]

http://www.vaccinationnews.com/chilling-impact-vaccine-autism-research

Chilling impact on vaccine-autism research

by Deth professor of pharmacology, offers his resonse to the

controversy surrounding a study linking a childhood vaccine to

autism.

January 10, 2011

The British medical journal, BMJ, has published a report by an

investigative journalist on the first study to link a childhood vaccine

to autism and inflammatory bowel disease. The article in the BMJ called

the study an " elaborate fraud, " and claimed that the

" appearance of a link with autism was manufactured at a London

medical school. "

Dr. Wakefield linked the measles, mumps, and rubella (MMR) vaccine

to autism in a study published in the medical journal Lancet more than 10

years ago. Lancet retracted the study last year after the British General

Medical Council found that Wakefield had acted " dishonestly and

irresponsibly " in his research.

Deth is a professor of pharmacology in the Bouvé College of

Health Sciences and the School of Pharmacy at Northeastern University.

His research suggests that vaccines containing aluminum and/or the

mercury-based preservative thimerosal could contribute to the development

of autism in children who lack the genetic capability to excrete

neurotoxic metals. The MMR vaccine does not contain aluminum or

thimerosal.

Deth, who is currently attending a vaccine safety conference with

Wakefield and other scientists, clinicians and legal experts, offers his

response to the controversy.

What are your thoughts on the BMJ report?

I think it’s very unusual, but at the same time revealing, that the BMJ

chose to publish this story. Investigative journalist Deer has been

on a mission to discredit Wakefield for years. His report is not a

scientific article, but rather an opinion piece that doesn’t focus on the

scientific finding of whether or not autistic children have inflammation

in their gastrointestinal tract, which I believe is the crux of the

original paper. That paper never set out to prove an explicit link

between autism and the MMR vaccine. Nobody studying 12 subjects could

conceive of proving a link. Wakefield found that subjects had

gastrointestinal inflammation and at least some of parents reported that

they thought this occurred after their children received the MMR

vaccine.

Our recent research has identified an amino acid transporter that may be

involved in gastrointestinal inflammation and might also contribute to

the neuronal inflammation that others have found in the brains of

autistic children. A connection between the gut and the brain in autism

makes sense to me.

What is the link between vaccines and autism?

Vaccines provoke an immune response to an antigen derived from a virus or

bacteria. They can also contain agents, called adjuvants, such as

aluminum, which augment the antibody response and can provoke

inflammation throughout the body, as well as preservatives such as

mercury, in the form of thimerosal.

Aluminum and mercury can enter the brain and remain for years, where they

provoke neuroinflammation. Inflammation during childhood can interfere

with the normal mechanisms by which gene expression is controlled,

leading to neurodevelopmental disorders such as autism.

While the MMR vaccine does not contain aluminum or mercury, simultaneous

exposure to these three viruses induces inflammation, which contributes

to the cumulative effect of vaccines on children.

It’s common for children to receive several vaccines in a single doctor’s

visit. As a result, they receive a tremendous dose of aluminum, well

beyond limits set by the U.S. Food and Drug Administration. This

increases the chance of excessive inflammation and a metabolic condition

known as oxidative stress, which can disrupt development and/or

precipitate regressive autism. Studies of autistic children show that

they have inflammation and oxidative stress.

Why haven't other studies shown a link between the MMR vaccine and

autism?

Most vaccine safety studies have been epidemiological in nature. They

examine large population-based datasets rather than individual autistic

subjects. The latter type of study has revealed the central role of

oxidative stress and inflammation, which could not be identified in

epidemiological studies.

Epidemiological studies are intrinsically unable to uncover causal

mechanisms, even if an association was found. In my view, MMR vaccination

is only a partial contributor, while other vaccines contribute to the

total risk of autism. Vaccines are certainly not the only agents

contributing to autism, but it’s likely that the major cause is some kind

of environmental exposure, as opposed to a genetic abnormality.

In light of this, should parents have their children vaccinated against

MMR and other diseases?

Yes. I support vaccination and safer vaccines that don't contain aluminum

or mercury.

Britain stripped Wakefield of his right to practice medicine. Was

this justified?

No, not in my opinion. The ethical issues he was found guilty of were not

of sufficient magnitude to justify this penalty. Moreover, doubt remains

about whether there was significant and willful misconduct.

The British General Medical Council and Deer have conspired to make

an example of Wakefield for daring to suggest that vaccination may cause

disease in some individuals.

Wakefield's identification of gastrointestinal inflammation in autism

will remain an important scientific contribution. The magnitude of the

effort to discredit him betrays a strong fear that his suggestion of a

link to vaccination may be correct. It amounts to a public pillorying

that frightens others from investigating this controversial but important

issue.

Sheri Nakken, former R.N., MA, Hahnemannian

Homeopath

Vaccination Information & Choice Network, Washington State, USA

Vaccines -

http://vaccinationdangers.wordpress.com/ Homeopathy

http://homeopathycures.wordpress.com

Vaccine Dangers, Childhood Disease Classes & Homeopathy

Online/email courses - next classes start February 4

[Guest guest]

http://www.vaccinationnews.com/chilling-impact-vaccine-autism-research

Chilling impact on vaccine-autism research

by Deth professor of pharmacology, offers his resonse to the

controversy surrounding a study linking a childhood vaccine to

autism.

January 10, 2011

The British medical journal, BMJ, has published a report by an

investigative journalist on the first study to link a childhood vaccine

to autism and inflammatory bowel disease. The article in the BMJ called

the study an " elaborate fraud, " and claimed that the

" appearance of a link with autism was manufactured at a London

medical school. "

Dr. Wakefield linked the measles, mumps, and rubella (MMR) vaccine

to autism in a study published in the medical journal Lancet more than 10

years ago. Lancet retracted the study last year after the British General

Medical Council found that Wakefield had acted " dishonestly and

irresponsibly " in his research.

Deth is a professor of pharmacology in the Bouvé College of

Health Sciences and the School of Pharmacy at Northeastern University.

His research suggests that vaccines containing aluminum and/or the

mercury-based preservative thimerosal could contribute to the development

of autism in children who lack the genetic capability to excrete

neurotoxic metals. The MMR vaccine does not contain aluminum or

thimerosal.

Deth, who is currently attending a vaccine safety conference with

Wakefield and other scientists, clinicians and legal experts, offers his

response to the controversy.

What are your thoughts on the BMJ report?

I think it’s very unusual, but at the same time revealing, that the BMJ

chose to publish this story. Investigative journalist Deer has been

on a mission to discredit Wakefield for years. His report is not a

scientific article, but rather an opinion piece that doesn’t focus on the

scientific finding of whether or not autistic children have inflammation

in their gastrointestinal tract, which I believe is the crux of the

original paper. That paper never set out to prove an explicit link

between autism and the MMR vaccine. Nobody studying 12 subjects could

conceive of proving a link. Wakefield found that subjects had

gastrointestinal inflammation and at least some of parents reported that

they thought this occurred after their children received the MMR

vaccine.

Our recent research has identified an amino acid transporter that may be

involved in gastrointestinal inflammation and might also contribute to

the neuronal inflammation that others have found in the brains of

autistic children. A connection between the gut and the brain in autism

makes sense to me.

What is the link between vaccines and autism?

Vaccines provoke an immune response to an antigen derived from a virus or

bacteria. They can also contain agents, called adjuvants, such as

aluminum, which augment the antibody response and can provoke

inflammation throughout the body, as well as preservatives such as

mercury, in the form of thimerosal.

Aluminum and mercury can enter the brain and remain for years, where they

provoke neuroinflammation. Inflammation during childhood can interfere

with the normal mechanisms by which gene expression is controlled,

leading to neurodevelopmental disorders such as autism.

While the MMR vaccine does not contain aluminum or mercury, simultaneous

exposure to these three viruses induces inflammation, which contributes

to the cumulative effect of vaccines on children.

It’s common for children to receive several vaccines in a single doctor’s

visit. As a result, they receive a tremendous dose of aluminum, well

beyond limits set by the U.S. Food and Drug Administration. This

increases the chance of excessive inflammation and a metabolic condition

known as oxidative stress, which can disrupt development and/or

precipitate regressive autism. Studies of autistic children show that

they have inflammation and oxidative stress.

Why haven't other studies shown a link between the MMR vaccine and

autism?

Most vaccine safety studies have been epidemiological in nature. They

examine large population-based datasets rather than individual autistic

subjects. The latter type of study has revealed the central role of

oxidative stress and inflammation, which could not be identified in

epidemiological studies.

Epidemiological studies are intrinsically unable to uncover causal

mechanisms, even if an association was found. In my view, MMR vaccination

is only a partial contributor, while other vaccines contribute to the

total risk of autism. Vaccines are certainly not the only agents

contributing to autism, but it’s likely that the major cause is some kind

of environmental exposure, as opposed to a genetic abnormality.

In light of this, should parents have their children vaccinated against

MMR and other diseases?

Yes. I support vaccination and safer vaccines that don't contain aluminum

or mercury.

Britain stripped Wakefield of his right to practice medicine. Was

this justified?

No, not in my opinion. The ethical issues he was found guilty of were not

of sufficient magnitude to justify this penalty. Moreover, doubt remains

about whether there was significant and willful misconduct.

The British General Medical Council and Deer have conspired to make

an example of Wakefield for daring to suggest that vaccination may cause

disease in some individuals.

Wakefield's identification of gastrointestinal inflammation in autism

will remain an important scientific contribution. The magnitude of the

effort to discredit him betrays a strong fear that his suggestion of a

link to vaccination may be correct. It amounts to a public pillorying

that frightens others from investigating this controversial but important

issue.

Sheri Nakken, former R.N., MA, Hahnemannian

Homeopath

Vaccination Information & Choice Network, Washington State, USA

Vaccines -

http://vaccinationdangers.wordpress.com/ Homeopathy

http://homeopathycures.wordpress.com

Vaccine Dangers, Childhood Disease Classes & Homeopathy

Online/email courses - next classes start February 4

[Guest guest]

http://www.vaccinationnews.com/chilling-impact-vaccine-autism-research

Chilling impact on vaccine-autism research

by Deth professor of pharmacology, offers his resonse to the

controversy surrounding a study linking a childhood vaccine to

autism.

January 10, 2011

The British medical journal, BMJ, has published a report by an

investigative journalist on the first study to link a childhood vaccine

to autism and inflammatory bowel disease. The article in the BMJ called

the study an " elaborate fraud, " and claimed that the

" appearance of a link with autism was manufactured at a London

medical school. "

Dr. Wakefield linked the measles, mumps, and rubella (MMR) vaccine

to autism in a study published in the medical journal Lancet more than 10

years ago. Lancet retracted the study last year after the British General

Medical Council found that Wakefield had acted " dishonestly and

irresponsibly " in his research.

Deth is a professor of pharmacology in the Bouvé College of

Health Sciences and the School of Pharmacy at Northeastern University.

His research suggests that vaccines containing aluminum and/or the

mercury-based preservative thimerosal could contribute to the development

of autism in children who lack the genetic capability to excrete

neurotoxic metals. The MMR vaccine does not contain aluminum or

thimerosal.

Deth, who is currently attending a vaccine safety conference with

Wakefield and other scientists, clinicians and legal experts, offers his

response to the controversy.

What are your thoughts on the BMJ report?

I think it’s very unusual, but at the same time revealing, that the BMJ

chose to publish this story. Investigative journalist Deer has been

on a mission to discredit Wakefield for years. His report is not a

scientific article, but rather an opinion piece that doesn’t focus on the

scientific finding of whether or not autistic children have inflammation

in their gastrointestinal tract, which I believe is the crux of the

original paper. That paper never set out to prove an explicit link

between autism and the MMR vaccine. Nobody studying 12 subjects could

conceive of proving a link. Wakefield found that subjects had

gastrointestinal inflammation and at least some of parents reported that

they thought this occurred after their children received the MMR

vaccine.

Our recent research has identified an amino acid transporter that may be

involved in gastrointestinal inflammation and might also contribute to

the neuronal inflammation that others have found in the brains of

autistic children. A connection between the gut and the brain in autism

makes sense to me.

What is the link between vaccines and autism?

Vaccines provoke an immune response to an antigen derived from a virus or

bacteria. They can also contain agents, called adjuvants, such as

aluminum, which augment the antibody response and can provoke

inflammation throughout the body, as well as preservatives such as

mercury, in the form of thimerosal.

Aluminum and mercury can enter the brain and remain for years, where they

provoke neuroinflammation. Inflammation during childhood can interfere

with the normal mechanisms by which gene expression is controlled,

leading to neurodevelopmental disorders such as autism.

While the MMR vaccine does not contain aluminum or mercury, simultaneous

exposure to these three viruses induces inflammation, which contributes

to the cumulative effect of vaccines on children.

It’s common for children to receive several vaccines in a single doctor’s

visit. As a result, they receive a tremendous dose of aluminum, well

beyond limits set by the U.S. Food and Drug Administration. This

increases the chance of excessive inflammation and a metabolic condition

known as oxidative stress, which can disrupt development and/or

precipitate regressive autism. Studies of autistic children show that

they have inflammation and oxidative stress.

Why haven't other studies shown a link between the MMR vaccine and

autism?

Most vaccine safety studies have been epidemiological in nature. They

examine large population-based datasets rather than individual autistic

subjects. The latter type of study has revealed the central role of

oxidative stress and inflammation, which could not be identified in

epidemiological studies.

Epidemiological studies are intrinsically unable to uncover causal

mechanisms, even if an association was found. In my view, MMR vaccination

is only a partial contributor, while other vaccines contribute to the

total risk of autism. Vaccines are certainly not the only agents

contributing to autism, but it’s likely that the major cause is some kind

of environmental exposure, as opposed to a genetic abnormality.

In light of this, should parents have their children vaccinated against

MMR and other diseases?

Yes. I support vaccination and safer vaccines that don't contain aluminum

or mercury.

Britain stripped Wakefield of his right to practice medicine. Was

this justified?

No, not in my opinion. The ethical issues he was found guilty of were not

of sufficient magnitude to justify this penalty. Moreover, doubt remains

about whether there was significant and willful misconduct.

The British General Medical Council and Deer have conspired to make

an example of Wakefield for daring to suggest that vaccination may cause

disease in some individuals.

Wakefield's identification of gastrointestinal inflammation in autism

will remain an important scientific contribution. The magnitude of the

effort to discredit him betrays a strong fear that his suggestion of a

link to vaccination may be correct. It amounts to a public pillorying

that frightens others from investigating this controversial but important

issue.

Sheri Nakken, former R.N., MA, Hahnemannian

Homeopath

Vaccination Information & Choice Network, Washington State, USA

Vaccines -

http://vaccinationdangers.wordpress.com/ Homeopathy

http://homeopathycures.wordpress.com

Vaccine Dangers, Childhood Disease Classes & Homeopathy

Online/email courses - next classes start February 4

[Guest guest]

http://www.vaccinationnews.com/chilling-impact-vaccine-autism-research

Chilling impact on vaccine-autism research

by Deth professor of pharmacology, offers his resonse to the

controversy surrounding a study linking a childhood vaccine to

autism.

January 10, 2011

The British medical journal, BMJ, has published a report by an

investigative journalist on the first study to link a childhood vaccine

to autism and inflammatory bowel disease. The article in the BMJ called

the study an " elaborate fraud, " and claimed that the

" appearance of a link with autism was manufactured at a London

medical school. "

Dr. Wakefield linked the measles, mumps, and rubella (MMR) vaccine

to autism in a study published in the medical journal Lancet more than 10

years ago. Lancet retracted the study last year after the British General

Medical Council found that Wakefield had acted " dishonestly and

irresponsibly " in his research.

Deth is a professor of pharmacology in the Bouvé College of

Health Sciences and the School of Pharmacy at Northeastern University.

His research suggests that vaccines containing aluminum and/or the

mercury-based preservative thimerosal could contribute to the development

of autism in children who lack the genetic capability to excrete

neurotoxic metals. The MMR vaccine does not contain aluminum or

thimerosal.

Deth, who is currently attending a vaccine safety conference with

Wakefield and other scientists, clinicians and legal experts, offers his

response to the controversy.

What are your thoughts on the BMJ report?

I think it’s very unusual, but at the same time revealing, that the BMJ

chose to publish this story. Investigative journalist Deer has been

on a mission to discredit Wakefield for years. His report is not a

scientific article, but rather an opinion piece that doesn’t focus on the

scientific finding of whether or not autistic children have inflammation

in their gastrointestinal tract, which I believe is the crux of the

original paper. That paper never set out to prove an explicit link

between autism and the MMR vaccine. Nobody studying 12 subjects could

conceive of proving a link. Wakefield found that subjects had

gastrointestinal inflammation and at least some of parents reported that

they thought this occurred after their children received the MMR

vaccine.

Our recent research has identified an amino acid transporter that may be

involved in gastrointestinal inflammation and might also contribute to

the neuronal inflammation that others have found in the brains of

autistic children. A connection between the gut and the brain in autism

makes sense to me.

What is the link between vaccines and autism?

Vaccines provoke an immune response to an antigen derived from a virus or

bacteria. They can also contain agents, called adjuvants, such as

aluminum, which augment the antibody response and can provoke

inflammation throughout the body, as well as preservatives such as

mercury, in the form of thimerosal.

Aluminum and mercury can enter the brain and remain for years, where they

provoke neuroinflammation. Inflammation during childhood can interfere

with the normal mechanisms by which gene expression is controlled,

leading to neurodevelopmental disorders such as autism.

While the MMR vaccine does not contain aluminum or mercury, simultaneous

exposure to these three viruses induces inflammation, which contributes

to the cumulative effect of vaccines on children.

It’s common for children to receive several vaccines in a single doctor’s

visit. As a result, they receive a tremendous dose of aluminum, well

beyond limits set by the U.S. Food and Drug Administration. This

increases the chance of excessive inflammation and a metabolic condition

known as oxidative stress, which can disrupt development and/or

precipitate regressive autism. Studies of autistic children show that

they have inflammation and oxidative stress.

Why haven't other studies shown a link between the MMR vaccine and

autism?

Most vaccine safety studies have been epidemiological in nature. They

examine large population-based datasets rather than individual autistic

subjects. The latter type of study has revealed the central role of

oxidative stress and inflammation, which could not be identified in

epidemiological studies.

Epidemiological studies are intrinsically unable to uncover causal

mechanisms, even if an association was found. In my view, MMR vaccination

is only a partial contributor, while other vaccines contribute to the

total risk of autism. Vaccines are certainly not the only agents

contributing to autism, but it’s likely that the major cause is some kind

of environmental exposure, as opposed to a genetic abnormality.

In light of this, should parents have their children vaccinated against

MMR and other diseases?

Yes. I support vaccination and safer vaccines that don't contain aluminum

or mercury.

Britain stripped Wakefield of his right to practice medicine. Was

this justified?

No, not in my opinion. The ethical issues he was found guilty of were not

of sufficient magnitude to justify this penalty. Moreover, doubt remains

about whether there was significant and willful misconduct.

The British General Medical Council and Deer have conspired to make

an example of Wakefield for daring to suggest that vaccination may cause

disease in some individuals.

Wakefield's identification of gastrointestinal inflammation in autism

will remain an important scientific contribution. The magnitude of the

effort to discredit him betrays a strong fear that his suggestion of a

link to vaccination may be correct. It amounts to a public pillorying

that frightens others from investigating this controversial but important

issue.

Sheri Nakken, former R.N., MA, Hahnemannian

Homeopath

Vaccination Information & Choice Network, Washington State, USA

Vaccines -

http://vaccinationdangers.wordpress.com/ Homeopathy

http://homeopathycures.wordpress.com

Vaccine Dangers, Childhood Disease Classes & Homeopathy

Online/email courses - next classes start February 4