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A low-dose intradermal hepatitis B vaccine programme in health-care workers and

students is highly effective and cost saving: A retrospective follow-up survey

in the clinical setting

Authors: Per Sangfelt a; Ingrid Uhnoo a; Olle Reichard b; Ola Weiland c

Affiliations: a Department of Infectious Diseases, Akademiska University

Hospital, Uppsala University, Uppsala, Sweden

b Department of Infectious Diseases, Karolinska University Hospital Solna,

c Department of Infectious Diseases, Karolinska University Hospital Huddinge,

Karolinska Institutet, Stockholm, Sweden

DOI: 10.1080/00365520701733806

Publication Frequency: 12 issues per year

Published in: Scandinavian Journal of Gastroenterology, Volume 43, Issue 4 2008

, pages 465 - 472

First Published on: 08 November 2007

Subjects: Gastroenterology; Gastrointestinal & Abdominal Surgery;

Formats available: HTML (English) : PDF (English)

Article Requests: Order Reprints : Request Permissions

Abstract

Objective. To evaluate compliance, serologic response and the cost-benefit of a

low-dose intradermal hepatitis B vaccination programme, followed by

intramuscular boosters in non-responders. Material and methods. The study

comprised a retrospective survey of 1521 health-care workers and 968 students.

Response was defined as hepatitis B antibody titres 10 IU/L. Non-response

included vaccinees with undetectable antibodies and a hypo-response if

antibodies were detectable. Results. Overall, 2145/2489 (86%) subjects completed

the intradermal series, whereof 1840/2489 (74%) complied with the serological

check-up. Response was achieved in 1517/1840 (82.5%), whereas 107/1840 (5.8%)

had a hypo-response and 216/1840 (11.7%) had an undetectable response. In a

logistic regression model, younger age (odds ratio 0.73 (95% CI: 0.65-0.82, p

_________________________________________________________________

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A low-dose intradermal hepatitis B vaccine programme in health-care workers and

students is highly effective and cost saving: A retrospective follow-up survey

in the clinical setting

Authors: Per Sangfelt a; Ingrid Uhnoo a; Olle Reichard b; Ola Weiland c

Affiliations: a Department of Infectious Diseases, Akademiska University

Hospital, Uppsala University, Uppsala, Sweden

b Department of Infectious Diseases, Karolinska University Hospital Solna,

c Department of Infectious Diseases, Karolinska University Hospital Huddinge,

Karolinska Institutet, Stockholm, Sweden

DOI: 10.1080/00365520701733806

Publication Frequency: 12 issues per year

Published in: Scandinavian Journal of Gastroenterology, Volume 43, Issue 4 2008

, pages 465 - 472

First Published on: 08 November 2007

Subjects: Gastroenterology; Gastrointestinal & Abdominal Surgery;

Formats available: HTML (English) : PDF (English)

Article Requests: Order Reprints : Request Permissions

Abstract

Objective. To evaluate compliance, serologic response and the cost-benefit of a

low-dose intradermal hepatitis B vaccination programme, followed by

intramuscular boosters in non-responders. Material and methods. The study

comprised a retrospective survey of 1521 health-care workers and 968 students.

Response was defined as hepatitis B antibody titres 10 IU/L. Non-response

included vaccinees with undetectable antibodies and a hypo-response if

antibodies were detectable. Results. Overall, 2145/2489 (86%) subjects completed

the intradermal series, whereof 1840/2489 (74%) complied with the serological

check-up. Response was achieved in 1517/1840 (82.5%), whereas 107/1840 (5.8%)

had a hypo-response and 216/1840 (11.7%) had an undetectable response. In a

logistic regression model, younger age (odds ratio 0.73 (95% CI: 0.65-0.82, p

_________________________________________________________________

How well do you know your celebrity gossip?

http://originals.msn.com/thebigdebate?ocid=T002MSN03N0707A

Link to comment
Share on other sites

Guest guest

A low-dose intradermal hepatitis B vaccine programme in health-care workers and

students is highly effective and cost saving: A retrospective follow-up survey

in the clinical setting

Authors: Per Sangfelt a; Ingrid Uhnoo a; Olle Reichard b; Ola Weiland c

Affiliations: a Department of Infectious Diseases, Akademiska University

Hospital, Uppsala University, Uppsala, Sweden

b Department of Infectious Diseases, Karolinska University Hospital Solna,

c Department of Infectious Diseases, Karolinska University Hospital Huddinge,

Karolinska Institutet, Stockholm, Sweden

DOI: 10.1080/00365520701733806

Publication Frequency: 12 issues per year

Published in: Scandinavian Journal of Gastroenterology, Volume 43, Issue 4 2008

, pages 465 - 472

First Published on: 08 November 2007

Subjects: Gastroenterology; Gastrointestinal & Abdominal Surgery;

Formats available: HTML (English) : PDF (English)

Article Requests: Order Reprints : Request Permissions

Abstract

Objective. To evaluate compliance, serologic response and the cost-benefit of a

low-dose intradermal hepatitis B vaccination programme, followed by

intramuscular boosters in non-responders. Material and methods. The study

comprised a retrospective survey of 1521 health-care workers and 968 students.

Response was defined as hepatitis B antibody titres 10 IU/L. Non-response

included vaccinees with undetectable antibodies and a hypo-response if

antibodies were detectable. Results. Overall, 2145/2489 (86%) subjects completed

the intradermal series, whereof 1840/2489 (74%) complied with the serological

check-up. Response was achieved in 1517/1840 (82.5%), whereas 107/1840 (5.8%)

had a hypo-response and 216/1840 (11.7%) had an undetectable response. In a

logistic regression model, younger age (odds ratio 0.73 (95% CI: 0.65-0.82, p

_________________________________________________________________

How well do you know your celebrity gossip?

http://originals.msn.com/thebigdebate?ocid=T002MSN03N0707A

Link to comment
Share on other sites

Guest guest

A low-dose intradermal hepatitis B vaccine programme in health-care workers and

students is highly effective and cost saving: A retrospective follow-up survey

in the clinical setting

Authors: Per Sangfelt a; Ingrid Uhnoo a; Olle Reichard b; Ola Weiland c

Affiliations: a Department of Infectious Diseases, Akademiska University

Hospital, Uppsala University, Uppsala, Sweden

b Department of Infectious Diseases, Karolinska University Hospital Solna,

c Department of Infectious Diseases, Karolinska University Hospital Huddinge,

Karolinska Institutet, Stockholm, Sweden

DOI: 10.1080/00365520701733806

Publication Frequency: 12 issues per year

Published in: Scandinavian Journal of Gastroenterology, Volume 43, Issue 4 2008

, pages 465 - 472

First Published on: 08 November 2007

Subjects: Gastroenterology; Gastrointestinal & Abdominal Surgery;

Formats available: HTML (English) : PDF (English)

Article Requests: Order Reprints : Request Permissions

Abstract

Objective. To evaluate compliance, serologic response and the cost-benefit of a

low-dose intradermal hepatitis B vaccination programme, followed by

intramuscular boosters in non-responders. Material and methods. The study

comprised a retrospective survey of 1521 health-care workers and 968 students.

Response was defined as hepatitis B antibody titres 10 IU/L. Non-response

included vaccinees with undetectable antibodies and a hypo-response if

antibodies were detectable. Results. Overall, 2145/2489 (86%) subjects completed

the intradermal series, whereof 1840/2489 (74%) complied with the serological

check-up. Response was achieved in 1517/1840 (82.5%), whereas 107/1840 (5.8%)

had a hypo-response and 216/1840 (11.7%) had an undetectable response. In a

logistic regression model, younger age (odds ratio 0.73 (95% CI: 0.65-0.82, p

_________________________________________________________________

How well do you know your celebrity gossip?

http://originals.msn.com/thebigdebate?ocid=T002MSN03N0707A

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