Significance of blood-related high-risk behaviors and horizontal transmission of hepatitis B Virus in Iran

[Guest guest]

Arch Virol. 2011 Jan 13. [Epub ahead of print]

Significance of blood-related high-risk behaviors and horizontal transmission of

hepatitis B Virus in Iran.

Abedi F, Madani H, Asadi A, Nejatizadeh A.

Research Center for Tropical and Infectious Disease (RCTI), Hormozgan University

of Medical Sciences, Bandar Abbas, Iran.

Abstract

Hepatitis B virus (HBV) is a significant public health problem and a leading

cause of morbidity and mortality, and approximately 30% of the world's

population is infected with HBV. The objective of our study was to determine the

seroprevalence of HBV and major risk factors associated with its occurrence.

Four thousand eighty-seven healthy Iranian subjects aged 8-80 years were

screened for HBV serological markers by an enzyme immunoassay method. A

structured questionnaire was administered to all participants. Multiple logistic

regression, an unpaired t-test for continuous data and the ÷ (2) test for

categorical data were performed. A total of 4087 participants were tested for

hepatitis B surface antigen (HBsAg), of which 62 (1.5%) were seropositive.

Fifteen percent of the subjects were positive for anti-HBs, 6.3% were positive

for isolated anti-HBc and 12.5% were positive for both anti-HBs and anti-HBc.

Laborers showed a higher HBsAg(+) seroprevalence and risk compared with jobless

participants (Pearson's = 8.276, P = 0.004; OR = 4.1, 95% CI: 1.5-11.2).

Bivariate logistic regression revealed that the following variables were

significantly associated with HBV seropositivity: phlebotomy (P = 0.002; OR =

5.0, 95% CI: 2.1-11.9), tattooing (P = 0.003; OR = 3.4, 95% CI: 1.6-7.0),

intravenous drug use (P = 0.001; OR = 2.4, 95% CI: 1.4-4.1). The adjusted

prevalence ratios remained significantly associated with HBV seropositivity and

thus likely served as possible risk factors for HBV. The overall positive

seroprevalence was 1.5%. Among the variables, only phlebotomy, tattooing and

intravenous drug injection emerged as major potential risk factors for hepatitis

B infection and responsible for transmission of the disease.

PMID: 21229276 [PubMed - as supplied by publisher]

[Guest guest]

Arch Virol. 2011 Jan 13. [Epub ahead of print]

Significance of blood-related high-risk behaviors and horizontal transmission of

hepatitis B Virus in Iran.

Abedi F, Madani H, Asadi A, Nejatizadeh A.

Research Center for Tropical and Infectious Disease (RCTI), Hormozgan University

of Medical Sciences, Bandar Abbas, Iran.

Abstract

Hepatitis B virus (HBV) is a significant public health problem and a leading

cause of morbidity and mortality, and approximately 30% of the world's

population is infected with HBV. The objective of our study was to determine the

seroprevalence of HBV and major risk factors associated with its occurrence.

Four thousand eighty-seven healthy Iranian subjects aged 8-80 years were

screened for HBV serological markers by an enzyme immunoassay method. A

structured questionnaire was administered to all participants. Multiple logistic

regression, an unpaired t-test for continuous data and the ÷ (2) test for

categorical data were performed. A total of 4087 participants were tested for

hepatitis B surface antigen (HBsAg), of which 62 (1.5%) were seropositive.

Fifteen percent of the subjects were positive for anti-HBs, 6.3% were positive

for isolated anti-HBc and 12.5% were positive for both anti-HBs and anti-HBc.

Laborers showed a higher HBsAg(+) seroprevalence and risk compared with jobless

participants (Pearson's = 8.276, P = 0.004; OR = 4.1, 95% CI: 1.5-11.2).

Bivariate logistic regression revealed that the following variables were

significantly associated with HBV seropositivity: phlebotomy (P = 0.002; OR =

5.0, 95% CI: 2.1-11.9), tattooing (P = 0.003; OR = 3.4, 95% CI: 1.6-7.0),

intravenous drug use (P = 0.001; OR = 2.4, 95% CI: 1.4-4.1). The adjusted

prevalence ratios remained significantly associated with HBV seropositivity and

thus likely served as possible risk factors for HBV. The overall positive

seroprevalence was 1.5%. Among the variables, only phlebotomy, tattooing and

intravenous drug injection emerged as major potential risk factors for hepatitis

B infection and responsible for transmission of the disease.

PMID: 21229276 [PubMed - as supplied by publisher]

[Guest guest]

Arch Virol. 2011 Jan 13. [Epub ahead of print]

Significance of blood-related high-risk behaviors and horizontal transmission of

hepatitis B Virus in Iran.

Abedi F, Madani H, Asadi A, Nejatizadeh A.

Research Center for Tropical and Infectious Disease (RCTI), Hormozgan University

of Medical Sciences, Bandar Abbas, Iran.

Abstract

Hepatitis B virus (HBV) is a significant public health problem and a leading

cause of morbidity and mortality, and approximately 30% of the world's

population is infected with HBV. The objective of our study was to determine the

seroprevalence of HBV and major risk factors associated with its occurrence.

Four thousand eighty-seven healthy Iranian subjects aged 8-80 years were

screened for HBV serological markers by an enzyme immunoassay method. A

structured questionnaire was administered to all participants. Multiple logistic

regression, an unpaired t-test for continuous data and the ÷ (2) test for

categorical data were performed. A total of 4087 participants were tested for

hepatitis B surface antigen (HBsAg), of which 62 (1.5%) were seropositive.

Fifteen percent of the subjects were positive for anti-HBs, 6.3% were positive

for isolated anti-HBc and 12.5% were positive for both anti-HBs and anti-HBc.

Laborers showed a higher HBsAg(+) seroprevalence and risk compared with jobless

participants (Pearson's = 8.276, P = 0.004; OR = 4.1, 95% CI: 1.5-11.2).

Bivariate logistic regression revealed that the following variables were

significantly associated with HBV seropositivity: phlebotomy (P = 0.002; OR =

5.0, 95% CI: 2.1-11.9), tattooing (P = 0.003; OR = 3.4, 95% CI: 1.6-7.0),

intravenous drug use (P = 0.001; OR = 2.4, 95% CI: 1.4-4.1). The adjusted

prevalence ratios remained significantly associated with HBV seropositivity and

thus likely served as possible risk factors for HBV. The overall positive

seroprevalence was 1.5%. Among the variables, only phlebotomy, tattooing and

intravenous drug injection emerged as major potential risk factors for hepatitis

B infection and responsible for transmission of the disease.

PMID: 21229276 [PubMed - as supplied by publisher]

[Guest guest]

Arch Virol. 2011 Jan 13. [Epub ahead of print]

Significance of blood-related high-risk behaviors and horizontal transmission of

hepatitis B Virus in Iran.

Abedi F, Madani H, Asadi A, Nejatizadeh A.

Research Center for Tropical and Infectious Disease (RCTI), Hormozgan University

of Medical Sciences, Bandar Abbas, Iran.

Abstract

Hepatitis B virus (HBV) is a significant public health problem and a leading

cause of morbidity and mortality, and approximately 30% of the world's

population is infected with HBV. The objective of our study was to determine the

seroprevalence of HBV and major risk factors associated with its occurrence.

Four thousand eighty-seven healthy Iranian subjects aged 8-80 years were

screened for HBV serological markers by an enzyme immunoassay method. A

structured questionnaire was administered to all participants. Multiple logistic

regression, an unpaired t-test for continuous data and the ÷ (2) test for

categorical data were performed. A total of 4087 participants were tested for

hepatitis B surface antigen (HBsAg), of which 62 (1.5%) were seropositive.

Fifteen percent of the subjects were positive for anti-HBs, 6.3% were positive

for isolated anti-HBc and 12.5% were positive for both anti-HBs and anti-HBc.

Laborers showed a higher HBsAg(+) seroprevalence and risk compared with jobless

participants (Pearson's = 8.276, P = 0.004; OR = 4.1, 95% CI: 1.5-11.2).

Bivariate logistic regression revealed that the following variables were

significantly associated with HBV seropositivity: phlebotomy (P = 0.002; OR =

5.0, 95% CI: 2.1-11.9), tattooing (P = 0.003; OR = 3.4, 95% CI: 1.6-7.0),

intravenous drug use (P = 0.001; OR = 2.4, 95% CI: 1.4-4.1). The adjusted

prevalence ratios remained significantly associated with HBV seropositivity and

thus likely served as possible risk factors for HBV. The overall positive

seroprevalence was 1.5%. Among the variables, only phlebotomy, tattooing and

intravenous drug injection emerged as major potential risk factors for hepatitis

B infection and responsible for transmission of the disease.

PMID: 21229276 [PubMed - as supplied by publisher]