Access to Treatment of Hepatitis C in Prison Inmates

[Guest guest]

Access to Treatment of Hepatitis C in Prison Inmates

Journal Digestive Diseases and Sciences

Publisher Springer Netherlands

ISSN 0163-2116 (Print) 1573-2568 (Online)

Category Original Article

DOI 10.1007/s10620-008-0483-8

Subject Collection Medicine

SpringerLink Date Saturday, August 30, 2008

Strock1 , Joël Mossong2, Karine Hawotte3 and Vic Arendt4

(1) Hepatogastroenterology, Service d’Hépato-Gastroentérologie, Centre

Hospitalier de Luxembourg, 4, rue Barblé, Luxembourg-City, 1210, Luxembourg

(2) Microbiology, Laboratoire National de Santé, Luxembourg-City, Luxembourg

(3) Retrovirology Laboratory, Centre Hospitalier de Luxembourg,

Luxembourg-City, Luxembourg

(4) Infectious Diseases, Centre Hospitalier de Luxembourg, Luxembourg-City,

Luxembourg

Received: 2 June 2008 Accepted: 31 July 2008 Published online: 29 August 2008

Abstract We conducted a prospective study to investigate access to treatment in

hepatitis C in 268 prisoners. Hepatitis C positivity had been known for 182

prisoners previously and 19 reported previous attempts to treat (10%). In

comparison, during our study, 86/268 prisoners (32%) started therapy (P <

0.0001). They represented 41% of 211 prisoners with a positive viral load. In

the genotype 2 or 3 group, 46 prisoners (50%) started therapy versus 40

prisoners (33%) with other genotypes (P = 0.01). This difference was due to

prisoners waiting for liver biopsy. On an intention to treat basis, 45 prisoners

(52%) achieved sustained virological response 6 months after the end of therapy.

We conclude that a stay in prison is an effective opportunity to treat a group

of hepatitis C patients which otherwise have very limited access to therapy.

Keywords Hepatitis C - Prison - Therapy - Epidemiology

This work was presented in part at the 15th United European Gastroenterology

Week, Paris, October 2007, and received no sponsorship.

--------------------------------------------------------------------------------

Strock

Email: strock.paul@...

[Guest guest]

Access to Treatment of Hepatitis C in Prison Inmates

Journal Digestive Diseases and Sciences

Publisher Springer Netherlands

ISSN 0163-2116 (Print) 1573-2568 (Online)

Category Original Article

DOI 10.1007/s10620-008-0483-8

Subject Collection Medicine

SpringerLink Date Saturday, August 30, 2008

Strock1 , Joël Mossong2, Karine Hawotte3 and Vic Arendt4

(1) Hepatogastroenterology, Service d’Hépato-Gastroentérologie, Centre

Hospitalier de Luxembourg, 4, rue Barblé, Luxembourg-City, 1210, Luxembourg

(2) Microbiology, Laboratoire National de Santé, Luxembourg-City, Luxembourg

(3) Retrovirology Laboratory, Centre Hospitalier de Luxembourg,

Luxembourg-City, Luxembourg

(4) Infectious Diseases, Centre Hospitalier de Luxembourg, Luxembourg-City,

Luxembourg

Received: 2 June 2008 Accepted: 31 July 2008 Published online: 29 August 2008

Abstract We conducted a prospective study to investigate access to treatment in

hepatitis C in 268 prisoners. Hepatitis C positivity had been known for 182

prisoners previously and 19 reported previous attempts to treat (10%). In

comparison, during our study, 86/268 prisoners (32%) started therapy (P <

0.0001). They represented 41% of 211 prisoners with a positive viral load. In

the genotype 2 or 3 group, 46 prisoners (50%) started therapy versus 40

prisoners (33%) with other genotypes (P = 0.01). This difference was due to

prisoners waiting for liver biopsy. On an intention to treat basis, 45 prisoners

(52%) achieved sustained virological response 6 months after the end of therapy.

We conclude that a stay in prison is an effective opportunity to treat a group

of hepatitis C patients which otherwise have very limited access to therapy.

Keywords Hepatitis C - Prison - Therapy - Epidemiology

This work was presented in part at the 15th United European Gastroenterology

Week, Paris, October 2007, and received no sponsorship.

--------------------------------------------------------------------------------

Strock

Email: strock.paul@...

[Guest guest]

Access to Treatment of Hepatitis C in Prison Inmates

Journal Digestive Diseases and Sciences

Publisher Springer Netherlands

ISSN 0163-2116 (Print) 1573-2568 (Online)

Category Original Article

DOI 10.1007/s10620-008-0483-8

Subject Collection Medicine

SpringerLink Date Saturday, August 30, 2008

Strock1 , Joël Mossong2, Karine Hawotte3 and Vic Arendt4

(1) Hepatogastroenterology, Service d’Hépato-Gastroentérologie, Centre

Hospitalier de Luxembourg, 4, rue Barblé, Luxembourg-City, 1210, Luxembourg

(2) Microbiology, Laboratoire National de Santé, Luxembourg-City, Luxembourg

(3) Retrovirology Laboratory, Centre Hospitalier de Luxembourg,

Luxembourg-City, Luxembourg

(4) Infectious Diseases, Centre Hospitalier de Luxembourg, Luxembourg-City,

Luxembourg

Received: 2 June 2008 Accepted: 31 July 2008 Published online: 29 August 2008

Abstract We conducted a prospective study to investigate access to treatment in

hepatitis C in 268 prisoners. Hepatitis C positivity had been known for 182

prisoners previously and 19 reported previous attempts to treat (10%). In

comparison, during our study, 86/268 prisoners (32%) started therapy (P <

0.0001). They represented 41% of 211 prisoners with a positive viral load. In

the genotype 2 or 3 group, 46 prisoners (50%) started therapy versus 40

prisoners (33%) with other genotypes (P = 0.01). This difference was due to

prisoners waiting for liver biopsy. On an intention to treat basis, 45 prisoners

(52%) achieved sustained virological response 6 months after the end of therapy.

We conclude that a stay in prison is an effective opportunity to treat a group

of hepatitis C patients which otherwise have very limited access to therapy.

Keywords Hepatitis C - Prison - Therapy - Epidemiology

This work was presented in part at the 15th United European Gastroenterology

Week, Paris, October 2007, and received no sponsorship.

--------------------------------------------------------------------------------

Strock

Email: strock.paul@...

[Guest guest]

Access to Treatment of Hepatitis C in Prison Inmates

Journal Digestive Diseases and Sciences

Publisher Springer Netherlands

ISSN 0163-2116 (Print) 1573-2568 (Online)

Category Original Article

DOI 10.1007/s10620-008-0483-8

Subject Collection Medicine

SpringerLink Date Saturday, August 30, 2008

Strock1 , Joël Mossong2, Karine Hawotte3 and Vic Arendt4

(1) Hepatogastroenterology, Service d’Hépato-Gastroentérologie, Centre

Hospitalier de Luxembourg, 4, rue Barblé, Luxembourg-City, 1210, Luxembourg

(2) Microbiology, Laboratoire National de Santé, Luxembourg-City, Luxembourg

(3) Retrovirology Laboratory, Centre Hospitalier de Luxembourg,

Luxembourg-City, Luxembourg

(4) Infectious Diseases, Centre Hospitalier de Luxembourg, Luxembourg-City,

Luxembourg

Received: 2 June 2008 Accepted: 31 July 2008 Published online: 29 August 2008

Abstract We conducted a prospective study to investigate access to treatment in

hepatitis C in 268 prisoners. Hepatitis C positivity had been known for 182

prisoners previously and 19 reported previous attempts to treat (10%). In

comparison, during our study, 86/268 prisoners (32%) started therapy (P <

0.0001). They represented 41% of 211 prisoners with a positive viral load. In

the genotype 2 or 3 group, 46 prisoners (50%) started therapy versus 40

prisoners (33%) with other genotypes (P = 0.01). This difference was due to

prisoners waiting for liver biopsy. On an intention to treat basis, 45 prisoners

(52%) achieved sustained virological response 6 months after the end of therapy.

We conclude that a stay in prison is an effective opportunity to treat a group

of hepatitis C patients which otherwise have very limited access to therapy.

Keywords Hepatitis C - Prison - Therapy - Epidemiology

This work was presented in part at the 15th United European Gastroenterology

Week, Paris, October 2007, and received no sponsorship.

--------------------------------------------------------------------------------

Strock

Email: strock.paul@...