Primary hepatocytes as targets for Hepatitis C virus replication

[Guest guest]

Primary hepatocytes as targets for Hepatitis C virus replication

Authors: Farquhar, M. J.; McKeating, J. A.

Source: Journal of Viral Hepatitis, Volume 15, Number 12, December 2008 , pp.

849-854(6)

Publisher: Blackwell Publishing

Abstract:

Summary. 

Much of our current understanding of hepatits C virus (HCV) replication has

hailed from the use of a small number of cloned viral genomes and transformed

hepatoma cell lines. Recent evidence suggests that lipoproteins play a key role

in the HCV life cycle and virus particles derived from the sera of infected

patients exist in association with host lipoproteins. This report will review

the literature on HCV replication in primary hepatocytes and transformed cell

lines, focusing largely on host factors defining particle entry.

[Guest guest]

Primary hepatocytes as targets for Hepatitis C virus replication

Authors: Farquhar, M. J.; McKeating, J. A.

Source: Journal of Viral Hepatitis, Volume 15, Number 12, December 2008 , pp.

849-854(6)

Publisher: Blackwell Publishing

Abstract:

Summary. 

Much of our current understanding of hepatits C virus (HCV) replication has

hailed from the use of a small number of cloned viral genomes and transformed

hepatoma cell lines. Recent evidence suggests that lipoproteins play a key role

in the HCV life cycle and virus particles derived from the sera of infected

patients exist in association with host lipoproteins. This report will review

the literature on HCV replication in primary hepatocytes and transformed cell

lines, focusing largely on host factors defining particle entry.

[Guest guest]

Primary hepatocytes as targets for Hepatitis C virus replication

Authors: Farquhar, M. J.; McKeating, J. A.

Source: Journal of Viral Hepatitis, Volume 15, Number 12, December 2008 , pp.

849-854(6)

Publisher: Blackwell Publishing

Abstract:

Summary. 

Much of our current understanding of hepatits C virus (HCV) replication has

hailed from the use of a small number of cloned viral genomes and transformed

hepatoma cell lines. Recent evidence suggests that lipoproteins play a key role

in the HCV life cycle and virus particles derived from the sera of infected

patients exist in association with host lipoproteins. This report will review

the literature on HCV replication in primary hepatocytes and transformed cell

lines, focusing largely on host factors defining particle entry.

[Guest guest]

Primary hepatocytes as targets for Hepatitis C virus replication

Authors: Farquhar, M. J.; McKeating, J. A.

Source: Journal of Viral Hepatitis, Volume 15, Number 12, December 2008 , pp.

849-854(6)

Publisher: Blackwell Publishing

Abstract:

Summary. 

Much of our current understanding of hepatits C virus (HCV) replication has

hailed from the use of a small number of cloned viral genomes and transformed

hepatoma cell lines. Recent evidence suggests that lipoproteins play a key role

in the HCV life cycle and virus particles derived from the sera of infected

patients exist in association with host lipoproteins. This report will review

the literature on HCV replication in primary hepatocytes and transformed cell

lines, focusing largely on host factors defining particle entry.