The Use of Selected Nutrition Supplements and Complementary and Alternative Medi

[Guest guest]

Nutrition in Clinical Practice, Vol. 21, No. 3, 2006 255-272

© 2006 American Society for Parenteral and Enteral Nutrition

This Article

--------------------------------------------------------------------------------

Invited Review

The Use of Selected Nutrition Supplements and Complementary and Alternative

Medicine in Liver Disease

A. Hanje, MD*, Brett Fortune, MD*, Ming Song, PhD, l Hill, MD

and Craig McClain, MD,

* Departments of Medicine, The Ohio State University, Columbus, Ohio;

University of Louisville, Louisville, Kentucky; and the Louisville VA

Medical Center, Louisville, Kentucky

Correspondence: Craig J. McClain, MD, Department of Internal Medicine,

Professor of Internal Medicine, Pharmacology and Toxicology, University of

Louisville Medical Center, 550 S St, ACB 3rd Floor, Louisville, KY

40292. Electronic mail may be sent to craig.mcclain@....

Almost all patients with liver disease, especially advanced liver disease,

have some evidence of malnutrition, including mineral/vitamin deficiency. A

major health trend in the United States has been the significant growth in

the use of complementary and alternative medicine (CAM), including nutrition

supplements and herbal agents. In the 1990s, the United States government

created the National Center for Complementary and Alternative Medicine

(NCCAM), as well as the Office on Dietary Supplements, to extend our

knowledge in these areas. CAM users are often highly educated and frequently

use CAM therapy for chronic diseases, including chronic liver disease.

Indeed, most studies suggest that patients with chronic liver disease

frequently use nutrition supplements and CAM agents in addition to their

traditional medicines. The purpose of this review is to provide an update on

the role of nutrition supplements and herbals in liver disease. This article

will focus mainly on 7 selected agents (vitamin E, zinc, magnesium,

S-adenosylmethionine, betaine, silymarin, and glycyrrhizin), for which there

have been not only in vitro and animal studies but also human clinical

trials, and we will review both potential efficacy and safety issues.

_________________________________________________________________

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[Guest guest]

Nutrition in Clinical Practice, Vol. 21, No. 3, 2006 255-272

© 2006 American Society for Parenteral and Enteral Nutrition

This Article

--------------------------------------------------------------------------------

Invited Review

The Use of Selected Nutrition Supplements and Complementary and Alternative

Medicine in Liver Disease

A. Hanje, MD*, Brett Fortune, MD*, Ming Song, PhD, l Hill, MD

and Craig McClain, MD,

* Departments of Medicine, The Ohio State University, Columbus, Ohio;

University of Louisville, Louisville, Kentucky; and the Louisville VA

Medical Center, Louisville, Kentucky

Correspondence: Craig J. McClain, MD, Department of Internal Medicine,

Professor of Internal Medicine, Pharmacology and Toxicology, University of

Louisville Medical Center, 550 S St, ACB 3rd Floor, Louisville, KY

40292. Electronic mail may be sent to craig.mcclain@....

Almost all patients with liver disease, especially advanced liver disease,

have some evidence of malnutrition, including mineral/vitamin deficiency. A

major health trend in the United States has been the significant growth in

the use of complementary and alternative medicine (CAM), including nutrition

supplements and herbal agents. In the 1990s, the United States government

created the National Center for Complementary and Alternative Medicine

(NCCAM), as well as the Office on Dietary Supplements, to extend our

knowledge in these areas. CAM users are often highly educated and frequently

use CAM therapy for chronic diseases, including chronic liver disease.

Indeed, most studies suggest that patients with chronic liver disease

frequently use nutrition supplements and CAM agents in addition to their

traditional medicines. The purpose of this review is to provide an update on

the role of nutrition supplements and herbals in liver disease. This article

will focus mainly on 7 selected agents (vitamin E, zinc, magnesium,

S-adenosylmethionine, betaine, silymarin, and glycyrrhizin), for which there

have been not only in vitro and animal studies but also human clinical

trials, and we will review both potential efficacy and safety issues.

_________________________________________________________________

Express yourself instantly with MSN Messenger! Download today - it's FREE!

http://messenger.msn.click-url.com/go/onm00200471ave/direct/01/

[Guest guest]

Nutrition in Clinical Practice, Vol. 21, No. 3, 2006 255-272

© 2006 American Society for Parenteral and Enteral Nutrition

This Article

--------------------------------------------------------------------------------

Invited Review

The Use of Selected Nutrition Supplements and Complementary and Alternative

Medicine in Liver Disease

A. Hanje, MD*, Brett Fortune, MD*, Ming Song, PhD, l Hill, MD

and Craig McClain, MD,

* Departments of Medicine, The Ohio State University, Columbus, Ohio;

University of Louisville, Louisville, Kentucky; and the Louisville VA

Medical Center, Louisville, Kentucky

Correspondence: Craig J. McClain, MD, Department of Internal Medicine,

Professor of Internal Medicine, Pharmacology and Toxicology, University of

Louisville Medical Center, 550 S St, ACB 3rd Floor, Louisville, KY

40292. Electronic mail may be sent to craig.mcclain@....

Almost all patients with liver disease, especially advanced liver disease,

have some evidence of malnutrition, including mineral/vitamin deficiency. A

major health trend in the United States has been the significant growth in

the use of complementary and alternative medicine (CAM), including nutrition

supplements and herbal agents. In the 1990s, the United States government

created the National Center for Complementary and Alternative Medicine

(NCCAM), as well as the Office on Dietary Supplements, to extend our

knowledge in these areas. CAM users are often highly educated and frequently

use CAM therapy for chronic diseases, including chronic liver disease.

Indeed, most studies suggest that patients with chronic liver disease

frequently use nutrition supplements and CAM agents in addition to their

traditional medicines. The purpose of this review is to provide an update on

the role of nutrition supplements and herbals in liver disease. This article

will focus mainly on 7 selected agents (vitamin E, zinc, magnesium,

S-adenosylmethionine, betaine, silymarin, and glycyrrhizin), for which there

have been not only in vitro and animal studies but also human clinical

trials, and we will review both potential efficacy and safety issues.

_________________________________________________________________

Express yourself instantly with MSN Messenger! Download today - it's FREE!

http://messenger.msn.click-url.com/go/onm00200471ave/direct/01/

[Guest guest]

Nutrition in Clinical Practice, Vol. 21, No. 3, 2006 255-272

© 2006 American Society for Parenteral and Enteral Nutrition

This Article

--------------------------------------------------------------------------------

Invited Review

The Use of Selected Nutrition Supplements and Complementary and Alternative

Medicine in Liver Disease

A. Hanje, MD*, Brett Fortune, MD*, Ming Song, PhD, l Hill, MD

and Craig McClain, MD,

* Departments of Medicine, The Ohio State University, Columbus, Ohio;

University of Louisville, Louisville, Kentucky; and the Louisville VA

Medical Center, Louisville, Kentucky

Correspondence: Craig J. McClain, MD, Department of Internal Medicine,

Professor of Internal Medicine, Pharmacology and Toxicology, University of

Louisville Medical Center, 550 S St, ACB 3rd Floor, Louisville, KY

40292. Electronic mail may be sent to craig.mcclain@....

Almost all patients with liver disease, especially advanced liver disease,

have some evidence of malnutrition, including mineral/vitamin deficiency. A

major health trend in the United States has been the significant growth in

the use of complementary and alternative medicine (CAM), including nutrition

supplements and herbal agents. In the 1990s, the United States government

created the National Center for Complementary and Alternative Medicine

(NCCAM), as well as the Office on Dietary Supplements, to extend our

knowledge in these areas. CAM users are often highly educated and frequently

use CAM therapy for chronic diseases, including chronic liver disease.

Indeed, most studies suggest that patients with chronic liver disease

frequently use nutrition supplements and CAM agents in addition to their

traditional medicines. The purpose of this review is to provide an update on

the role of nutrition supplements and herbals in liver disease. This article

will focus mainly on 7 selected agents (vitamin E, zinc, magnesium,

S-adenosylmethionine, betaine, silymarin, and glycyrrhizin), for which there

have been not only in vitro and animal studies but also human clinical

trials, and we will review both potential efficacy and safety issues.

_________________________________________________________________

Express yourself instantly with MSN Messenger! Download today - it's FREE!

http://messenger.msn.click-url.com/go/onm00200471ave/direct/01/