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Psychiatric disorder in early adulthood and risk of premature mortality in the 1946 British Birth Cohort

Max , Hotopf , Imran Shah , D and Kuh

BMC Psychiatry 2011, 11:37doi:10.1186/1471-244X-11-37

Published:

8 March 2011

Abstract (provisional)

Background

Few studies of the association between psychiatric disorder and premature death have adjusted for key confounders and used structured psychiatric interviews. We aimed to investigate if psychiatric disorder was associated with a higher risk of premature mortality and whether any excess mortality was due to suicide, or explained by other health or socioeconomic risk factors.

Methods

We used data from the MRC National Survey of Health and Development, a nationally representative UK birth cohort. 3283 men and women completed the Present State Examination at age 36. The main outcome measure was all-cause mortality before age 60.

Results

Those with psychiatric disorder at age 36 had a higher risk of death even after adjusting for potential confounders (Hazard ratio=1.84, 95% C.I. 1.22-2.78). Censoring violent deaths and suicides led to similar results.

Conclusions

Psychiatric disorder was associated with excess premature mortality not explained by suicide or other health or socioeconomic risk factors.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.

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Psychiatric disorder in early adulthood and risk of premature mortality in the 1946 British Birth Cohort

Max , Hotopf , Imran Shah , D and Kuh

BMC Psychiatry 2011, 11:37doi:10.1186/1471-244X-11-37

Published:

8 March 2011

Abstract (provisional)

Background

Few studies of the association between psychiatric disorder and premature death have adjusted for key confounders and used structured psychiatric interviews. We aimed to investigate if psychiatric disorder was associated with a higher risk of premature mortality and whether any excess mortality was due to suicide, or explained by other health or socioeconomic risk factors.

Methods

We used data from the MRC National Survey of Health and Development, a nationally representative UK birth cohort. 3283 men and women completed the Present State Examination at age 36. The main outcome measure was all-cause mortality before age 60.

Results

Those with psychiatric disorder at age 36 had a higher risk of death even after adjusting for potential confounders (Hazard ratio=1.84, 95% C.I. 1.22-2.78). Censoring violent deaths and suicides led to similar results.

Conclusions

Psychiatric disorder was associated with excess premature mortality not explained by suicide or other health or socioeconomic risk factors.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.

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Share on other sites

Guest guest

Psychiatric disorder in early adulthood and risk of premature mortality in the 1946 British Birth Cohort

Max , Hotopf , Imran Shah , D and Kuh

BMC Psychiatry 2011, 11:37doi:10.1186/1471-244X-11-37

Published:

8 March 2011

Abstract (provisional)

Background

Few studies of the association between psychiatric disorder and premature death have adjusted for key confounders and used structured psychiatric interviews. We aimed to investigate if psychiatric disorder was associated with a higher risk of premature mortality and whether any excess mortality was due to suicide, or explained by other health or socioeconomic risk factors.

Methods

We used data from the MRC National Survey of Health and Development, a nationally representative UK birth cohort. 3283 men and women completed the Present State Examination at age 36. The main outcome measure was all-cause mortality before age 60.

Results

Those with psychiatric disorder at age 36 had a higher risk of death even after adjusting for potential confounders (Hazard ratio=1.84, 95% C.I. 1.22-2.78). Censoring violent deaths and suicides led to similar results.

Conclusions

Psychiatric disorder was associated with excess premature mortality not explained by suicide or other health or socioeconomic risk factors.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.

Link to comment
Share on other sites

Guest guest

Psychiatric disorder in early adulthood and risk of premature mortality in the 1946 British Birth Cohort

Max , Hotopf , Imran Shah , D and Kuh

BMC Psychiatry 2011, 11:37doi:10.1186/1471-244X-11-37

Published:

8 March 2011

Abstract (provisional)

Background

Few studies of the association between psychiatric disorder and premature death have adjusted for key confounders and used structured psychiatric interviews. We aimed to investigate if psychiatric disorder was associated with a higher risk of premature mortality and whether any excess mortality was due to suicide, or explained by other health or socioeconomic risk factors.

Methods

We used data from the MRC National Survey of Health and Development, a nationally representative UK birth cohort. 3283 men and women completed the Present State Examination at age 36. The main outcome measure was all-cause mortality before age 60.

Results

Those with psychiatric disorder at age 36 had a higher risk of death even after adjusting for potential confounders (Hazard ratio=1.84, 95% C.I. 1.22-2.78). Censoring violent deaths and suicides led to similar results.

Conclusions

Psychiatric disorder was associated with excess premature mortality not explained by suicide or other health or socioeconomic risk factors.

The complete article is available as a provisional PDF. The fully formatted PDF and HTML versions are in production.

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