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Reduction of enuresis - clinical evidence

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Reduction of enuresis

Compared with placebo Imipramine and desipramine are more effective at reducing the number of wet nights and at achieving 14 consecutive dry nights (high-quality evidence).

Compared with enuresis alarm Tricyclics are less effective at achieving 14 consecutive dry nights at 8 to 14 weeks (high-quality evidence).

Tricyclics plus enuresis alarm compared with alarm alone Imipramine plus an enuresis alarm may be no more effective at reducing wet nights at 6 months (low-quality evidence).

Compared with desmopressin We don't know whether the tricyclic drugs amitriptyline and imipramine are more effective at reducing the number of wet nights (low-quality evidence).

Compared with anticholinergic Imipramine may be more effective than the anticholinergic tolterodine in reducing the number of wet nights (low-quality evidence).

Tricyclics plus anticholinergics compared with placebo Imipramine plus the anticholinergic oxybutynin seems more effective at reducing wet nights (moderate-quality evidence).

Tricyclics plus anticholinergics compared with tricyclics alone Imipramine plus the anticholinergic oxybutynin may be more effective than imipramine alone at increasing cure rates (very low-quality evidence).

Tricyclics plus anticholinergics compared with anticholinergics alone Imipramine plus the anticholinergic oxybutynin may be more effective than oxybutynin alone at increasing cure rates (very low-quality evidence).

read on - http://bestpractice.bmj.com/best-practice/monograph/690/treatment/evidence/intervention/0305/0/sr-0305-i3.html

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Reduction of enuresis

Compared with placebo Imipramine and desipramine are more effective at reducing the number of wet nights and at achieving 14 consecutive dry nights (high-quality evidence).

Compared with enuresis alarm Tricyclics are less effective at achieving 14 consecutive dry nights at 8 to 14 weeks (high-quality evidence).

Tricyclics plus enuresis alarm compared with alarm alone Imipramine plus an enuresis alarm may be no more effective at reducing wet nights at 6 months (low-quality evidence).

Compared with desmopressin We don't know whether the tricyclic drugs amitriptyline and imipramine are more effective at reducing the number of wet nights (low-quality evidence).

Compared with anticholinergic Imipramine may be more effective than the anticholinergic tolterodine in reducing the number of wet nights (low-quality evidence).

Tricyclics plus anticholinergics compared with placebo Imipramine plus the anticholinergic oxybutynin seems more effective at reducing wet nights (moderate-quality evidence).

Tricyclics plus anticholinergics compared with tricyclics alone Imipramine plus the anticholinergic oxybutynin may be more effective than imipramine alone at increasing cure rates (very low-quality evidence).

Tricyclics plus anticholinergics compared with anticholinergics alone Imipramine plus the anticholinergic oxybutynin may be more effective than oxybutynin alone at increasing cure rates (very low-quality evidence).

read on - http://bestpractice.bmj.com/best-practice/monograph/690/treatment/evidence/intervention/0305/0/sr-0305-i3.html

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Reduction of enuresis

Compared with placebo Imipramine and desipramine are more effective at reducing the number of wet nights and at achieving 14 consecutive dry nights (high-quality evidence).

Compared with enuresis alarm Tricyclics are less effective at achieving 14 consecutive dry nights at 8 to 14 weeks (high-quality evidence).

Tricyclics plus enuresis alarm compared with alarm alone Imipramine plus an enuresis alarm may be no more effective at reducing wet nights at 6 months (low-quality evidence).

Compared with desmopressin We don't know whether the tricyclic drugs amitriptyline and imipramine are more effective at reducing the number of wet nights (low-quality evidence).

Compared with anticholinergic Imipramine may be more effective than the anticholinergic tolterodine in reducing the number of wet nights (low-quality evidence).

Tricyclics plus anticholinergics compared with placebo Imipramine plus the anticholinergic oxybutynin seems more effective at reducing wet nights (moderate-quality evidence).

Tricyclics plus anticholinergics compared with tricyclics alone Imipramine plus the anticholinergic oxybutynin may be more effective than imipramine alone at increasing cure rates (very low-quality evidence).

Tricyclics plus anticholinergics compared with anticholinergics alone Imipramine plus the anticholinergic oxybutynin may be more effective than oxybutynin alone at increasing cure rates (very low-quality evidence).

read on - http://bestpractice.bmj.com/best-practice/monograph/690/treatment/evidence/intervention/0305/0/sr-0305-i3.html

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Reduction of enuresis

Compared with placebo Imipramine and desipramine are more effective at reducing the number of wet nights and at achieving 14 consecutive dry nights (high-quality evidence).

Compared with enuresis alarm Tricyclics are less effective at achieving 14 consecutive dry nights at 8 to 14 weeks (high-quality evidence).

Tricyclics plus enuresis alarm compared with alarm alone Imipramine plus an enuresis alarm may be no more effective at reducing wet nights at 6 months (low-quality evidence).

Compared with desmopressin We don't know whether the tricyclic drugs amitriptyline and imipramine are more effective at reducing the number of wet nights (low-quality evidence).

Compared with anticholinergic Imipramine may be more effective than the anticholinergic tolterodine in reducing the number of wet nights (low-quality evidence).

Tricyclics plus anticholinergics compared with placebo Imipramine plus the anticholinergic oxybutynin seems more effective at reducing wet nights (moderate-quality evidence).

Tricyclics plus anticholinergics compared with tricyclics alone Imipramine plus the anticholinergic oxybutynin may be more effective than imipramine alone at increasing cure rates (very low-quality evidence).

Tricyclics plus anticholinergics compared with anticholinergics alone Imipramine plus the anticholinergic oxybutynin may be more effective than oxybutynin alone at increasing cure rates (very low-quality evidence).

read on - http://bestpractice.bmj.com/best-practice/monograph/690/treatment/evidence/intervention/0305/0/sr-0305-i3.html

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