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RE: Re: new study- potential treatment for CD

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Thanks for the insight . I totally concur.

I am very concerned about drugs, blockers, modified foods developed to fool the body and get around the root issue - which is why the body is now reacting and treating these and other foods as an antigen? I also have a concern that if over cultivated, over process foods like wheat, dairy, soy, corn ...are becoming more common allergens and detrimental to our bodies - what is the next on the list of common allergens...rice, chicken, apples?

From: [mailto: ] On Behalf Of li_cynthiaSent: Thursday, February 24, 2011 10:03 AM Subject: [ ] Re: new study- potential treatment for CD

Thanks for the fascinating article. I posted on the blog and have copied it here (I highly recommend people who are interested in this subject to read other posts on the blog; a very good dialogue):As an internist and new celiac, all of your concerns and hopes are valid. Yes, inflammatory blockers are exciting, but they can have multiple side-effects, not to mention prohibitive costs. Most of the research is in a treatment or a cure, b/c that is where the money is-- it's sexy and innovative. Pharmaceuticals are great when you *really * need them and it is the last resort; but oftentimes, they can make our bodies even more imbalanced. What is so much more healthful and sustainable, as many above have mentioned, is to allow our bodies to heal themselves naturally with whole foods and lifestyle changes (I mean these on a cultural level, not just having the individual deal with it in a blameworthy fashion, which happens all too often). Below is an article I find incredibly promising-- the idea behind it is that these researchers in The Netherlands have compared our modern wheat varieties with varieties from up to 100 years ago. They tested one of the specific gluten epitopes known to trigger inflammatory T-cells in CD and found that it is much higher in content in modern wheat varieties than in those pre-industrialization. On top of that, they found much less genetic variation in gluten epitopes used today, which again, can help explain why CD and gluten sensitivity is exploding these days. They go on to suggest that not only could switching back to older varieties likely prevent those w/ genetic susceptibility to CD from developing the active disease, but that it could help reduce symptoms of current CD patients. This is exciting b/c this truly goes back to the etiology of why CD/gluten problems are becoming more prevalent. This is the direction we ought to be looking in, since a new pill or treatment can so often times lead to further unforeseen problems. The problem with this approach, of course, is that it is not a new sexy man-made solution that can be packaged and marketed. But does anyone out there know of ways in which we can promote this kind of research? Comments welcome! https://mail-attachment.googleusercontent.com/attachment?ui=2 & ik=0c4328e653 & view=att & th=12c75eab3c141efe & attid=0.2 & disp=inline & realattid=f_ggtzm5tq1 & safe=1 & zw & saduie=AG9B_P86ok71_3qXCOAr9mfvg0zB & sadet=1298569036545 & sads=GAg61fdxYNjNQmEgF_spAPCsVuk & sadssc=1--- In , "j. hogle" <jjhogle@...> wrote:>> Thanks. Interesting research. As you say, it's probably quite a number of > years before reaching Phase 3 human trials. > > > Currently, the greatest hopes seem to be the drugs or enzymes being developed to > ameliorate the effects of inadvertent gluttening: AT1001, ALV003, STAN1 enzyme, > and CCX282-B. > > > Hogle> Freelance academic librarian> Instructor, online research> Email: jjhogle@...> Web: (under de- and re-construction) www.blueroom.com> > > Reality ain't what you think it is> Art Graphics & Photographs> [http://www.blueroom.com/realityaint.htm]> > > > > > ________________________________> From: alisonjhughes25 <alison.j.hughes@...>> > Sent: Wed, February 23, 2011 9:09:55 AM> Subject: [ ] new study- potential treatment for CD> > > has anyone seen this?> http://www.triumphdining.com/blog/gluten-free/2011/02/good-news-for-celiac-treatment-comes-in-a-small-package/?utm_source=Triumph+Dining+List & utm_campaign=060d3eeddd-Newsletter_Feb22_Stickers_Intro2_23_2011 & utm_medium=email> > > The results are of course preliminary (in a mouse model) and would need further > research, and IF this could be an effective treatment we would still be about > 10-15 years away from being able to have this, but it's still exciting that they > are getting closer.>

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