RE: RE: Low Body Weight and CR -- Both Help You

[Guest guest]

Thanks, Warren!

Exercise may not make life longer, but, I find, it makes life better, more

enjoyable.

>From: " Warren " <warren.taylor@...>

>Reply-

>< >, Subject: [ ] RE: Low

>Body Weight and CR -- Both Help You

>Date: Mon, 1 Mar 2004 22:17:55 -0800

>

>This article on exercise (a variable that is independent of both

>body weight and CR) has results that I found interesting. The effect

>of exercise increased lifespan by 9% in the following study -- but

>was not statistically significant within measurement error for

>the animal cohort sample size used in the study. -- Warren

>

>======================

>[1] Mech Ageing Dev 1998 Feb 16;100(3):211-9 Related Articles, Books,

>LinkOut

>

>Longevity of exercising male rats: effect of an antioxidant supplemented

>diet.

>

>Holloszy JO.

>

>Department of Medicine, Washington University School of Medicine, St.

>Louis,

>MO 63110, USA.

>

>Food restriction increases maximal life span in rodents. Male rats that

>exercise in voluntary running wheels do not have an increase in maximal

>longevity despite a relative caloric deficit. In contrast, sedentary rats

>that are food restricted so as to cause the same caloric deficit have an

>extension of maximal longevity. It seemed possible that exercise-induced

>oxidative stress might prevent a maximum life span-extending effect of a

>caloric deficit to manifest itself. This study was done to determine if

>antioxidants would allow a maximal longevity-extending effect of exercise

>to

>manifest itself in male rats. The antioxidant diet had no effect on

>longevity of the runners (Antiox., 951 +/- 158 days versus control 937 +

>171

>days), or of the sedentary controls (875 +/- 127 versus 858 +/- 152 days).

>As in previous studies, wheel running modestly increased average longevity

>(approximately 9%), but had no effect on maximal life span. The finding

>that

>antioxidants had no effect on longevity of the wheel runners supports the

>interpretation that the caloric deficit induced by exercise in male rats

>does not have a life-extending effect that is countered by oxidative tissue

>damage.

>

>PMID: 9578110

>

>