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Re: BMI and Mortality

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Rodney: the BMI's seem rather high by CR standards, don''t they? Mine is

20, and I'm not one of the extremely thin CRONIES by any means. According

to this, I'm under the optimum for long life (that is if I calculated

correctly). Whereas, by CRONIE standards, I'm not anywhere near what some

might consider " thin " or low BMI.

Also one also wonders if they lump the feeble, the sick and the frail (who

usually are very thin) into these factors. (They really shouldn't be

because that skews the healthy thin numbers).

on 3/8/2004 6:54 AM, Rodney at perspect1111@... wrote:

> Hi folks:

>

> Take a look at the two charts shown here:

>

> http://www.jr2.ox.ac.uk/bandolier/booth/hliving/BMIwords.html

>

> or at: http://snipurl.com/4y94

>

> Rodney.

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Hi Francesca:

" ... with no history of disease " . So counting in the sick does not

explain it.

But possibly in those who are intrinsically thin and apparently

healthy, their thinness (perhaps because of the lack of a 'healthy'

appetite) is a symptom of some as yet undiagnosed problem? It would

be interesting to know what the causes of death were among the low

body mass individuals.

Or ......... if we believe both this and Walford then the issue may

be how to maintain higher body mass with lower caloric

intake ........... calcium supplements and lean-body-mass-building

exercise?

Rodney.

> Also one also wonders if they lump the feeble, the sick and the

frail (who

> usually are very thin) into these factors. (They really shouldn't

be

> because that skews the healthy thin numbers).

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Just like obesity is the result of multiple factors (activity level,

consumption, and conversion efficiency or ability to extract energy from

calories consumed), thinness will also be caused by come combination of

these same factors. Trying to extract simple conclusions from multiple

causal factors is never easy.

IMO BMI is too conflicted to be a very reliable metric. Perhaps more

meaningful might be %BF as researchers continue to find hormonal influences

from our adipose mass. Also calories expended in work and normal bodily

functions might eliminate conversion efficiency as an error term.

It is very likely that favorable results are the combination of multiple

factors. Our best guess is that DR (eating less) is the most powerful

" common " factor. How much, and how to is still a work in process and not

likely to result in one answer fits all.

My personal choice is to not lose sleep over perfecting an answer but

practice moderation with continuous incremental improvement. I've seen too

many precise answers discredited over time to think we now know all the

answers. IMO, based on our current level of understanding, extreme practice

has as much chance of doing harm as doing good. Don't ask me to define what

extreme is. I can't, but like pornography I know it when I see it.....

JR

-----Original Message-----

From: Rodney [mailto:perspect1111@...]

Sent: Monday, March 08, 2004 8:24 AM

Subject: [ ] Re: BMI and Mortality

Hi Francesca:

" ... with no history of disease " . So counting in the sick does not

explain it.

But possibly in those who are intrinsically thin and apparently

healthy, their thinness (perhaps because of the lack of a 'healthy'

appetite) is a symptom of some as yet undiagnosed problem? It would

be interesting to know what the causes of death were among the low

body mass individuals.

Or ......... if we believe both this and Walford then the issue may

be how to maintain higher body mass with lower caloric

intake ........... calcium supplements and lean-body-mass-building

exercise?

Rodney.

> Also one also wonders if they lump the feeble, the sick and the

frail (who

> usually are very thin) into these factors. (They really shouldn't

be

> because that skews the healthy thin numbers).

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What it doesn't say is what happens if I drop from BMI 27 to 24, by whatever means other than illness.

Do I get the benefits of the 24 group?

Regards.

----- Original Message -----

From: Francesca Skelton

Sent: Monday, March 08, 2004 8:01 AM

Subject: Re: [ ] BMI and Mortality

Rodney: the BMI's seem rather high by CR standards, don''t they? Mine is20, and I'm not one of the extremely thin CRONIES by any means. Accordingto this, I'm under the optimum for long life (that is if I calculatedcorrectly). Whereas, by CRONIE standards, I'm not anywhere near what somemight consider "thin" or low BMI.Also one also wonders if they lump the feeble, the sick and the frail (whousually are very thin) into these factors. (They really shouldn't bebecause that skews the healthy thin numbers).on 3/8/2004 6:54 AM, Rodney at perspect1111@... wrote:> Hi folks:> > Take a look at the two charts shown here:> > http://www.jr2.ox.ac.uk/bandolier/booth/hliving/BMIwords.html> > or at: http://snipurl.com/4y94> > Rodney.

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Hi folks:

Perhaps this is the way to think about these data:

One can speculate that among a group of mice that have access to lots

of very tasty and calorically dense foods (as humans do these days)

the majority will be overweight and a few thin, just like the present

north american human population. So in this situation, as in the

case of humans, not many will be thin 'voluntarily'. Most will be

overweight.

But when a group of mice are all subjected to CR not only are

the 'voluntarily thin' ones thin, even those with a 'healthy

appetite' who would like to be fat, are thin also. Forcibly so.

Perhaps it is the mice with a big appetite, those that would like to

be fat if they were not constrained by food shortage, that account

for the benefits seen in CR mice. While the few who would be

voluntarily thin even with high availability of food, do not benefit

because of some cause (problem) of which their voluntary thinness is

a marker.

The thin individuals in the human case I linked earlier, were thin

because of what might be called the 'voluntary marker' (i.e. problem).

This is one possible way to reconcile the data sets we are talking

about.

Rodney.

>

> > Hi folks:

> >

> > Take a look at the two charts shown here:

> >

> > http://www.jr2.ox.ac.uk/bandolier/booth/hliving/BMIwords.html

> >

> > or at: http://snipurl.com/4y94

> >

> > Rodney.

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