Fish Oil supplementation studies

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Studies have shown that heart attack survivors who take fish oil

supplements have fewer cardiac deaths than controls:

http://tinyurl.com/3e2k7

http://tinyurl.com/2zqr5

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http://tinyurl.com/3e2k7Cardiovasc Drugs Ther. 1997

The findings of this study suggest that fish oil and mustard oil, possibly due to the presence of n-3 fatty acids, may provide rapid protective effects in patients with AMI. However, a large study is necessary to confirm this suggestion.http://tinyurl.com/2zqr5March 10, 1999All of the patients were following directions to eat a more healthful diet -- which means adding plenty of fruits and vegetables and cutting fat -- and exercising, Tognoni said. They were also trying to eat fish instead of meat twice a week.

The patients also received medication for heart attack patients, including anti-clotting drugs, beta-blockers and ACE inhibitors.

Tognoni said it is not fully understood why fish oil, which contains omega-3 fatty acids, benefits heart patients.

He said there is some evidence the fatty acids work on the inside lining of blood vessels, which become clogged with fatty plaques in heart disease.

Other good sources of omega-3 fatty acids are canola oil, flaxseed and flaxseed oil.

Braunwald: Heart Disease: A Textbook of Cardiovascular Medicine, 6th ed., Copyright © 2001

"The reduced incidence of atherosclerotic cardiovascular disease in Greenland Eskimos has been attributed, at least in part, to their diets rich in fish oils containing omega-3 polyunsaturated fatty acids. A major omega-3 fatty acid in fish oils is eicosapentaenoic acid (EPA), which incorporates into cell membrane phospholipids and competes with arachidonic acid as substrate for COX. The product of EPA oxygenation is TXA3 , an eicosanoid that is devoid of the potent platelet activating and vasoconstrictor actions of arachidonic acid–derived TXA2 . Large and often unpalatable doses (> 10 gm EPA daily) of medicinal fish oils are required to simulate changes in platelet membrane fatty acid content attained with Eskimo diets and thereby produce antiplatelet actions."

{avoid AA - don't eat meats, Niacin maybe?}

Regards.

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From: Clyde

Sent: Saturday, March 20, 2004 10:56 AM

Subject: [ ] Fish Oil supplementation studies

Studies have shown that heart attack survivors who take fish oil supplements have fewer cardiac deaths than controls:http://tinyurl.com/3e2k7http://tinyurl.com/2zqr5