Re: Alternate Fasting vs. Caloric Restriction

[Guest guest]

--- In , " Rodney " <perspect1111@y...>

wrote:

> Hi Hermit:

>

> If you are aware of studies in any kind of mammal which show that

> fasting groups live as long as CR groups, please post a link to it

> because it will be of great interest to everyone here.

>

======

There was an article in January about Alternate Fasting (eating every

other day without caloric restriction). The benefits were supposed

to be equal to Caloric Restriction.

Here is a quote from Newsweek Jan 26 issue from this link:

http://msnbc.msn.com/id/3990725/

" Meanwhile, scientists are looking at ways to get some of the

presumed benefits of CR without actually forcing people to skip lunch

for the rest of their lives. One approach is to tinker with eating

patterns in a way that might be easier for most people to sustain,

such as intermittent fasting. Neuroscientist Mark Mattson at the U.S.

National Institute on Aging has run experiments on mice that were fed

nothing on alternate days, and double rations the rest of the time.

They didn't lose weight, but they showed changes in blood pressure

and heart rate that suggested a lower risk of cardiovascular disease.

The " mild stress " of fasting seemed to have inoculated them against

more severe forms of stress that ordinarily cause adverse reactions

in mice, Mattson speculates. He hopes to begin testing the

proposition in humans soon. "

Live long and prosper,

A. Zamora

http://www.scientificpsychic.com/fitness/index.html

[Guest guest]

Hi Citpeks:

The thing that is absolutely remarkable about CR is its, so far,

unique ability to extend **maximum** lifespan. And to do so

substantially in experimental animals.

I believe the study that article referred to was this one in the

PNAS: " Intermittent fasting dissociates beneficial effects of

dietary restriction on glucose metabolism and neuronal resistance to

injury from calorie intake " - Anson et al. (and Mattson)

Unfortunately, that study did not look at the lifepan of the mice.

They did test blood glucose and insulin, and the numbers were even

better than for CR, but other numbers were not as good as on CR.

If indeed it is in due course shown that fasting can extend maximum

lifespan then, as I understand it, it will be the very first time

anything other than CR has been shown to have that effect.

In the meantime I am likely to stay with what we know for sure, at

least for experimental animals, and, by inference, probably for

humans.

Incidentally a couple of months ago I emailed two prominent fasting

gurus asking if they could refer me to studies demonstrating an

increase in maximum lifespan of any mammalian species from fasting.

Both replied, but neither was able to provide any such evidence.

I am not saying that fasting will not extend maximum lifespan. I

don't know if it will or not, because I am not aware of any of the

kind of evidence I would need to have in order to formulate an

opinion. As I have said, I hope it does. That would be better for

me.

Rodney.

> > Hi Hermit:

> >

> > If you are aware of studies in any kind of mammal which show that

> > fasting groups live as long as CR groups, please post a link to

it

> > because it will be of great interest to everyone here.

> >

> ======

>

> There was an article in January about Alternate Fasting (eating

every

> other day without caloric restriction). The benefits were supposed

> to be equal to Caloric Restriction.

>

> Here is a quote from Newsweek Jan 26 issue from this link:

> http://msnbc.msn.com/id/3990725/

>

> " Meanwhile, scientists are looking at ways to get some of the

> presumed benefits of CR without actually forcing people to skip

lunch

> for the rest of their lives. One approach is to tinker with eating

> patterns in a way that might be easier for most people to sustain,

> such as intermittent fasting. Neuroscientist Mark Mattson at the

U.S.

> National Institute on Aging has run experiments on mice that were

fed

> nothing on alternate days, and double rations the rest of the time.

> They didn't lose weight, but they showed changes in blood pressure

> and heart rate that suggested a lower risk of cardiovascular

disease.

> The " mild stress " of fasting seemed to have inoculated them against

> more severe forms of stress that ordinarily cause adverse reactions

> in mice, Mattson speculates. He hopes to begin testing the

> proposition in humans soon. "

>

>

> Live long and prosper,

> A. Zamora

> http://www.scientificpsychic.com/fitness/index.html

[Guest guest]

--- In , " Rodney " <perspect1111@y...>

wrote:

> If indeed it is in due course shown that fasting can extend maximum

> lifespan then, as I understand it, it will be the very first time

> anything other than CR has been shown to have that effect.

Hi All,

I appear to recall a number of articles on fasting and lifespan that

found either no effect of fasting or an effect apparently due to

unintentional CR/weight loss.

Cheers, Al Pater.