Guest guest Posted April 16, 2004 Report Share Posted April 16, 2004 Hi folks: I see this did not format too well: The lower half shows the vitamin and 'mineral' pre-mixes that are referred to in the nutrient list in the top half. The left side is the mineral premix and the right side the vitamin premix. What is the most important though for our purposes is the proportions of them in the two diets in the top half of the page. Rodney. --- In , " Rodney " <perspect1111@y...> wrote: > Hi folks: > > OK. I got permission to reproduce the data here. So here they are > for a start. More information (analysis) in subsequent posts. > > Rodney. > > The following data, for the control and CR diets in Dr. Spindler's > very recently published study, is very kindly provided by: > > Yisheng Bai. Ph.D. > Director of Nutrition > Bio-Serv > One 8th Street, Suite One > Frenchtown, NJ 08825 > PH: 908-996-2155 ext. 117 > PH: 800-996-9908 ext. 117 > FAX: 908-996-4123 > > > Ingredient List > Bio-Servís Formulas of F05312, F05314, F05553 > > Dustless Precision Pellets, 1 gm, Rodent Diet, AIN-93M > Control (F05312), 40% DR (F05314) > > F05312 F05314 > Ingredient gm/kg gm/kg > Casein 140.00 233.33 > Sucrose 100.00 200.00 > Fiber 40.00 57.80 > Dextrin 470.00 355.00 > Starch 160.70 5.00 > Salt Mix (AIN-93MMX) 35.00 58.30 > Soybean oil 40.00 66.70 > Vitamin Mix (AIN-93MVX)10.00 16.70 > L-Cystine 1.80 3.00 > Choline Bitartrate 2.50 4.20 > > ------------------------- > > 1. Mineral Premix, AIN-93MMX 2. Vitamin Premix, AIN-93MVX > Ingredient (g/kg mix) Ingredient (g/kg mix) > Calcium carbonate, anhydrous 357.00 Nicotinic acid 3.000 > Potassium phosphat, monobasic 250.00 Calcium pantothenate 1.600 > > Potassium sulfate 46.60 Pyridoxine-HCl 0.700 > Potassium citrate tri-K, H2O 28.00 Thiamin-HCl 0.600 > Sodium chloride 74.00 Riboflavin 0.600 > Magnesium oxide 24.00 Folic acid 0.200 > Ferric citrate 6.06 d-Biotin 0.020 > Zinc carbonate 1.65 Vitamin B12(0.1% mannitol) > Manganous carbonate 0.63 2.500 > Cupric carbonate 0.30 Vitamin E acetate(500 IU/g) > 15.000 > Potasium iodate 0.01 Vitamin A palmitate > Sodium selenate, anhydrate 0.01025 (500,000 IU/g) 0.800 > Ammonium paramolybdate , 4H2O 0.00795 Vitamin D3(400,000 IU/g)0.250 > Sodium meta-silicate, 9H2O 1.4500 Vitamin K1 0.075 > Chromium potassium sulfate, 0.2750 Powdered sucrose 974.655 > Lithium chloride 0.0174 > Boric acid 0.0815 > Sodium fluoride 0.0635 > Nickel carbonate 0.0318 > Ammonium vanadate 0.0066 > Powdered sucrose 209.8060 > > Prepared by Dr. Yisheng Bai, Bio-Serv > > Revised date: 2/7/02 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 17, 2004 Report Share Posted April 17, 2004 This is perhaps interesting for those without enough to micro-manage. While I don't wish to encourage that there will be substantive value at the end of this pursuit, here is a link to Rat vs., Human RDAs. Mouse RDA is supposed to be similar to Rats. http://www.rmca.org/Articles/homemadediet.htm have fun.... JR -----Original Message----- From: Rodney [mailto:perspect1111@...] Sent: Friday, April 16, 2004 5:23 PM Subject: [ ] Dr. Spindler's Mice Hi folks: OK. I got permission to reproduce the data here. So here they are for a start. More information (analysis) in subsequent posts. Rodney. The following data, for the control and CR diets in Dr. Spindler's very recently published study, is very kindly provided by: Yisheng Bai. Ph.D. Director of Nutrition Bio-Serv One 8th Street, Suite One Frenchtown, NJ 08825 PH: 908-996-2155 ext. 117 PH: 800-996-9908 ext. 117 FAX: 908-996-4123 Ingredient List Bio-Servís Formulas of F05312, F05314, F05553 Dustless Precision Pellets, 1 gm, Rodent Diet, AIN-93M Control (F05312), 40% DR (F05314) F05312 F05314 Ingredient gm/kg gm/kg Casein 140.00 233.33 Sucrose 100.00 200.00 Fiber 40.00 57.80 Dextrin 470.00 355.00 Starch 160.70 5.00 Salt Mix (AIN-93MMX) 35.00 58.30 Soybean oil 40.00 66.70 Vitamin Mix (AIN-93MVX)10.00 16.70 L-Cystine 1.80 3.00 Choline Bitartrate 2.50 4.20 ------------------------- 1. Mineral Premix, AIN-93MMX 2. Vitamin Premix, AIN-93MVX Ingredient (g/kg mix) Ingredient (g/kg mix) Calcium carbonate, anhydrous 357.00 Nicotinic acid 3.000 Potassium phosphat, monobasic 250.00 Calcium pantothenate 1.600 Potassium sulfate 46.60 Pyridoxine-HCl 0.700 Potassium citrate tri-K, H2O 28.00 Thiamin-HCl 0.600 Sodium chloride 74.00 Riboflavin 0.600 Magnesium oxide 24.00 Folic acid 0.200 Ferric citrate 6.06 d-Biotin 0.020 Zinc carbonate 1.65 Vitamin B12(0.1% mannitol) Manganous carbonate 0.63 2.500 Cupric carbonate 0.30 Vitamin E acetate(500 IU/g) 15.000 Potasium iodate 0.01 Vitamin A palmitate Sodium selenate, anhydrate 0.01025 (500,000 IU/g) 0.800 Ammonium paramolybdate , 4H2O 0.00795 Vitamin D3(400,000 IU/g)0.250 Sodium meta-silicate, 9H2O 1.4500 Vitamin K1 0.075 Chromium potassium sulfate, 0.2750 Powdered sucrose 974.655 Lithium chloride 0.0174 Boric acid 0.0815 Sodium fluoride 0.0635 Nickel carbonate 0.0318 Ammonium vanadate 0.0066 Powdered sucrose 209.8060 Prepared by Dr. Yisheng Bai, Bio-Serv Revised date: 2/7/02 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 17, 2004 Report Share Posted April 17, 2004 Hi folks: More on the diets of Dr. Spindler's mice. I find these data fascinating not only because of the fact that some of the mice lived 42% longer than the others. In addition to that remarkable finding, consider the following: [As a reminder ..... in order to see the data in this table much better formatted click the 'reply' button and view it in the reply window that pops up]. Does anyone remember the science fiction magazine stories of fifty years ago, when it was quite popular to speculate that the world was going to run out of food and we would all be eating just pills made of chemicals? Well we (or at least Dr. Spindler's mice at least) have arrived. Take a look at this diet, which, incidentally, does an excellent job of feeding these mice. Pretty much the only item which might be considered to be more complex than a known organic molecule is 'soybean oil'. Most of the items are just simple inorganic molecules like sodium chloride, zinc carbonate, potassium iodate etc... Others are a bit more complex, but still well known, relatively straightforward organic molecules, like starch or dextrin or sucrose. Even soybean oil, pretty much the only 'non-chemical' on the list, is a mixture of, for the most part, well known (organic) fat molecules. Now in my opinion this is interesting not only because it shows we have 'arrived' in a science fiction sense, but also because it clearly demonstrates that science now knows ***all*** the specific chemical substances that we animals need to keep ourselves alive. I have argued here before that we need variety in our diet because you never know what trace nutrients there may be in some healthy food that does wonders for our health that science as yet knows nothing about. LOL (at myself). Well these data are a powerful argument AGAINST that point of view. I still believe, based on such known epidemiological evidence as that which shows certain foods (cruciform vegetables, tea, for example) are associated with quite powerful protection against cancer, that there are micronutrients science still knows nothing about that can help optimize our health. But that seems to be a matter of the little details. The bulk of nutrition science seems to be very firmly understood, as demonstrated by the survival to very decent ages of these mice on the Bio-Serv cocktail of specific chemical nutrients. Rodney. --- In , " Rodney " <perspect1111@y...> wrote: > Hi folks: > > OK. I got permission to reproduce the data here. So here they are > for a start. More information (analysis) in subsequent posts. > > Rodney. > > The following data, for the control and CR diets in Dr. Spindler's > very recently published study, is very kindly provided by: > > Yisheng Bai. Ph.D. > Director of Nutrition > Bio-Serv > One 8th Street, Suite One > Frenchtown, NJ 08825 > PH: 908-996-2155 ext. 117 > PH: 800-996-9908 ext. 117 > FAX: 908-996-4123 > > > Ingredient List > Bio-Servís Formulas of F05312, F05314, F05553 > > Dustless Precision Pellets, 1 gm, Rodent Diet, AIN-93M > Control (F05312), 40% DR (F05314) > > F05312 F05314 > Ingredient gm/kg gm/kg > Casein 140.00 233.33 > Sucrose 100.00 200.00 > Fiber 40.00 57.80 > Dextrin 470.00 355.00 > Starch 160.70 5.00 > Salt Mix (AIN-93MMX) 35.00 58.30 > Soybean oil 40.00 66.70 > Vitamin Mix (AIN-93MVX)10.00 16.70 > L-Cystine 1.80 3.00 > Choline Bitartrate 2.50 4.20 > > ------------------------- > > 1. Mineral Premix, AIN-93MMX 2. Vitamin Premix, AIN-93MVX > Ingredient (g/kg mix) Ingredient (g/kg mix) > Calcium carbonate, anhydrous 357.00 Nicotinic acid 3.000 > Potassium phosphat, monobasic 250.00 Calcium pantothenate 1.600 > > Potassium sulfate 46.60 Pyridoxine-HCl 0.700 > Potassium citrate tri-K, H2O 28.00 Thiamin-HCl 0.600 > Sodium chloride 74.00 Riboflavin 0.600 > Magnesium oxide 24.00 Folic acid 0.200 > Ferric citrate 6.06 d-Biotin 0.020 > Zinc carbonate 1.65 Vitamin B12(0.1% mannitol) > Manganous carbonate 0.63 2.500 > Cupric carbonate 0.30 Vitamin E acetate(500 IU/g) > 15.000 > Potasium iodate 0.01 Vitamin A palmitate > Sodium selenate, anhydrate 0.01025 (500,000 IU/g) 0.800 > Ammonium paramolybdate , 4H2O 0.00795 Vitamin D3(400,000 IU/g)0.250 > Sodium meta-silicate, 9H2O 1.4500 Vitamin K1 0.075 > Chromium potassium sulfate, 0.2750 Powdered sucrose 974.655 > Lithium chloride 0.0174 > Boric acid 0.0815 > Sodium fluoride 0.0635 > Nickel carbonate 0.0318 > Ammonium vanadate 0.0066 > Powdered sucrose 209.8060 > > Prepared by Dr. Yisheng Bai, Bio-Serv > > Revised date: 2/7/02 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 18, 2004 Report Share Posted April 18, 2004 Hi folks: Another detail. The intermediate period of 25% CR in Dr. Spindler's mice lasted two weeks. Assuming an approximately 40:1 human/mouse lifespan ratio, the intermediate period, in human terms, was about eighteen months. Rodney. --- In , " Rodney " <perspect1111@y...> wrote: > Hi folks: > > More on the diets of Dr. Spindler's mice. Quote Link to comment Share on other sites More sharing options...
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