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Dr. Spindler's Mice (continued)

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Hi folks:

Diet F05314 is designed in such a way that, in comparison with mice

fed F05312, mice fed 40% less of F05314 will consume 40% fewer

calories but very nearly identical amounts of all nutrients except

carbohydrates. And the entire reduction in calories is achieved by a

reduction in the amount of carbohydrate.

Further, in summary, for almost every nutrient the CR feed, F05314,

contains 67% more grams of nutrient per kilogram of feed than does

the control feed, # F05312. This includes 67% more casein (the major

protein source) and 67% more soybean oil (the principal source of

fat). The result is that when one feeds 40% less (grams) of F05314

the mice are eating the same amounts of all the above nutrients as

the control mice.

There are four nutrients which, in the CR feed, are not 67% higher

(grams of nutrient per kilogram of feed) than in the control diet.

They are starch, dextrin, fiber and sucrose. To cut a longish story

short it appears that the CR mice consumed 98% less starch; 55% less

dextrin; 14% less fibre; and 20% more (sic) sucrose (compared with

the control mice, in absolute terms).

As a reminder ......... after going on this 43.9% CR diet at

age '60-65', in a two step process, the mice lived 42% longer than

those eating a 10% CR diet - equivalent, perhaps, to a ~twelve year

difference in humans.

Quite interesting.

Rodney.

(It looks like white sugar may not be as bad as some would have us

believe!)

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