Re: Re: Seven-year study suggests longer lifecomes from higher metabolism

[Guest guest]

Not necessarily- exercise might result in the creation of more free radicals

(inefficient mitochonria) vs. uncoupling (effecient mitochondrial

metabolism).

>From: Francesca Skelton <fskelton@...>

>Reply-

>< >

>Subject: Re: [ ] Re: " Seven-year study suggests longer

>lifecomes from higher metabolism "

>Date: Thu, 24 Jun 2004 13:34:10 -0400

>

>Doesn't this also fly in the face of " too much exercise is bad? " If lots

>of exercise is one way to get " thin " ?

>

>

>on 6/24/2004 1:22 PM, aequalsz at aequalsz@... wrote:

>

> >

> >> For the shallow-thinking among us, would someone care to explain

> > why

> >> this is not a complete repudiation of CRON?

> >>

> >> And if not, how the two theories fit together and how to get the

> >> benefits of both.

> >>

> >> Don

> >>

> >

> >

> > My guess is that " thin " is good for longevity. Whether it is due to

> > a hyperactive metabolism or a CRON diet or a combination of both.

> > Mainly to avoid obesity related health problems. (Or maybe over-

> > oxidation due to free radicals. Also fat seems to be a good way to

> > store toxic elements - not good).

> >

> > Anyone notice that animal studies seem to show a lessoning of

> > effectiveness of CRON diets to extend lifespan for larger, longer-

> > lived animals? Am thinking about a study of some Labrador Retriever

> > dogs who had a 15% increase in lifespan due to a CRON diet. But

> > vaguely remember something about mice and fruit flies that lived

> > proportionately much longer than that. Am wondering if by the time

> > you get to Homo Sapiens that the CRON effect will not be too

> > significant in extending lifespan.

> >

> > aequalsz

> >

> >

> >

> >

[Guest guest]

Correction: Efficiencies would appear to be reversed (i.e.

uncoupling=inefficient but low free radical production; exercise=possibly

efficient but with more free radical production and aging effects.)

>From: " Dowling " <dowlic@...>

>Reply-

>

>Subject: Re: [ ] Re: " Seven-year study suggests longer

>lifecomes from higher metabolism "

>Date: Thu, 24 Jun 2004 17:47:02 +0000

>

>Not necessarily- exercise might result in the creation of more free

>radicals

>(inefficient mitochonria) vs. uncoupling (effecient mitochondrial

>metabolism).

>

>

> >From: Francesca Skelton <fskelton@...>

> >Reply-

> >< >

> >Subject: Re: [ ] Re: " Seven-year study suggests longer

> >lifecomes from higher metabolism "

> >Date: Thu, 24 Jun 2004 13:34:10 -0400

> >

> >Doesn't this also fly in the face of " too much exercise is bad? " If

>lots

> >of exercise is one way to get " thin " ?

> >

> >

> >on 6/24/2004 1:22 PM, aequalsz at aequalsz@... wrote:

> >

> > >

> > >> For the shallow-thinking among us, would someone care to explain

> > > why

> > >> this is not a complete repudiation of CRON?

> > >>

> > >> And if not, how the two theories fit together and how to get the

> > >> benefits of both.

> > >>

> > >> Don

> > >>

> > >

> > >

> > > My guess is that " thin " is good for longevity. Whether it is due to

> > > a hyperactive metabolism or a CRON diet or a combination of both.

> > > Mainly to avoid obesity related health problems. (Or maybe over-

> > > oxidation due to free radicals. Also fat seems to be a good way to

> > > store toxic elements - not good).

> > >

> > > Anyone notice that animal studies seem to show a lessoning of

> > > effectiveness of CRON diets to extend lifespan for larger, longer-

> > > lived animals? Am thinking about a study of some Labrador Retriever

> > > dogs who had a 15% increase in lifespan due to a CRON diet. But

> > > vaguely remember something about mice and fruit flies that lived

> > > proportionately much longer than that. Am wondering if by the time

> > > you get to Homo Sapiens that the CRON effect will not be too

> > > significant in extending lifespan.

> > >

> > > aequalsz

> > >

> > >

> > >

> > >