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Ancient DNA Mutations

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Permitted Humans To Adapt To Colder Climates, Researchers Find

That last article, about test mice that used more oxygen, had a

faster metabolism, and produced more heat, (and lived longer)

reminded me of this article I read a few months ago.

http://www.sciencedaily.com/releases/2004/01/040114075853.htm

" Consider two individuals that eat the same number of calories and

get the same amount of exercise. The individual with a mtDNA mutant

that increases heat production will require more calories for energy

production and thus will have fewer calories left over to produce

oxygen radicals. This individual will be partially protected from

age-related diseases and will live longer. By contrast, the

individual with mitochondria that make more ATP per calorie burned

will store fat and generate more oxygen radicals if he or she eats

the same level of calories as the individual with the cold-adapted

mitochondria. "

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