Re: New Cholesterol guidelines

[Guest guest]

----- Original Message -----

Subject: [ ] New Cholesterol guidelines

>New LDL cholesterol guidelines just came out today. This represents

>a major change from the prior NCEP guidelines.

>Here's a news story that discusses it.

>If anyone has access to the report itself, appreciate an e-mail with

>it. I believe this is coming out tomorrow in the journal Circulation.

This post to another group presents some interesting points in regards to this:

> > The American Heart Association just announced a new lowered ldl

> > target for at risk adults from 100 to 70.

>

> That follows their incorrect dogma that low-density cholesterol

> causes problems; of course, it has never been proven. Oxidation does

> cause plaque to build up, and plaque has been proven to be comprised

> mainly of dietary unsaturated and polyunsaturated oils (74%).

>

> Another way of looking at it is that just as many people with normal

> cholesterol as high cholesterol have heart disease. The Heart

> Foundation only wishes a larger percentage of the population to

> use cholesterol-lowering drugs, which deplete coenzyme Q-10, causing

> muscle wasting, including to the heart muscle, and energy

> depletion, which carries a heart attack risk.

>

> The Oiling Of America is a good document, full of references, written

> by the world's top oils researcher.

>

> Our best defense is to not eat oxidizing polyunsaturated oils, and to

> take antioxidants. If you must, you can reduce LDL and VLDL levels

> naturally with food -- coconut oil and inulin, and also by increasing

> your natural growth hormone secretion with amino acids. Considering

> that low growth hormone levels have been proven to be behind

> metabolic syndrome, amino acids are an anti-aging tool that makes a

> lot of sense.

>

> Anti-aging specialists, the past president and V.P. of the American

> Academy of Anti-Aging in fact, say that they have never seen any drug

> or natural product that normalizes cholesterol and blood pressure as

> well as youthful HGH levels. They use SomaLife gHP in their practice

> in preference to HGH shots.

>

> regards,

>

> Duncan Crow

[Guest guest]

Hi All,

Please see the pdf-available below.

Cheers, Al Pater.

Circulation. 2004;110:227-239.

Implications of Recent Clinical Trials for the National Cholesterol

Education Program Adult Treatment Panel III Guidelines.

Grundy, M.; Cleeman, I.; Merz, C. Noel Bairey;

Brewer,

H. Jr; , Luther T.; Hunninghake, B. *; Pasternak,

C.; , Sidney C. Jr; Stone, Neil J.; for the Coordinating

Committee of the National Cholesterol Education Program[NCEP Report]

Abstract—The Adult Treatment Panel III (ATP III) of

the National Cholesterol Education Program issued an

evidence-based set of guidelines on cholesterol management

in 2001. Since the publication of ATP III, 5 major clinical

trials of statin therapy with clinical end points have been

published. These trials addressed issues that were not examined

in previous clinical trials of cholesterol-lowering therapy.

The present document reviews the results of these recent trials

and assesses their implications for cholesterol management.

Therapeutic lifestyle changes (TLC) remain an essential

modality in clinical management. The trials confirm

the benefit of cholesterol-lowering therapy in high-risk patients and

support the ATP III treatment goal of low-density

lipoprotein cholesterol (LDL-C) <100 mg/dL. They support the

inclusion of patients with diabetes in the high-risk category

and confirm the benefits of LDL-lowering therapy in these

patients. They further confirm that older persons benefit

from therapeutic lowering of LDL-C. The major recommen-dations

for modifications to footnote the ATP III treatment

algorithm are the following. In high-risk persons, the

recommended LDL-C goal is <100 mg/dL, but when risk

is very high, an LDL-C goal of <70 mg/dL is a therapeutic

option, ie, a reasonable clinical strategy, on the basis of

available clinical trial evidence. This therapeutic option extends

also to patients at very high risk who have a baseline

LDL-C <100 mg/dL. Moreover, when a high-risk patient has high

triglycerides or low high-density lipoprotein cholesterol

(HDL-C), consideration can be given to combining a fibrate or

nicotinic acid with an LDL-lowering drug. For moderately

high-risk persons (2 risk factors and 10-year risk 10% to

20%), the recommended LDL-C goal is <130 mg/dL, but

an LDL-C goal <100 mg/dL is a therapeutic option on the

basis of recent trial evidence. The latter option extends

also to moderately high-risk persons with a baseline LDL-C of

100 to 129 mg/dL. When LDL-lowering drug therapy is

employed in high-risk or moderately high-risk persons, it is

advised that intensity of therapy be sufficient to achieve

at least a 30% to 40% reduction in LDL-C levels. Moreover,

any person at high risk or moderately high risk who has

lifestyle-related risk factors (eg, obesity, physical inactivity,

elevated triglycerides, low HDL-C, or metabolic syndrome)

is a candidate for TLC to modify these risk factors

regardless of LDL-C level. Finally, for people in lower-risk

categories, recent clinical trials do not modify the goals and

cutpoints of therapy.

Key Words: cholesterol trials lipoproteins coronary disease

> New LDL cholesterol guidelines just came out today. This

represents

> a major change from the prior NCEP guidelines.

> Here's a news story that discusses it.

> If anyone has access to the report itself, appreciate an e-mail

with

> it. I believe this is coming out tomorrow in the journal

Circulation.

>

> rjb112@y...

> ------------------------------

>

> Experts Urge a New Low for Cholesterol

>

> By Salynn Boyles

> WebMD Medical News Reviewed By Brunilda Nazario, MD

> on Monday, July 12, 2004

>

> July 12, 2004 -- The nation's top heart groups are calling for more

> aggressive cholesterol treatment of people at the highest risk of

> dying from heart attacks and strokes.

>

>

> The message from the clinical trials that prompted the guideline

> changes is clear, the experts say. When it comes to low-density

> lipoprotein (LDL), or " bad, " cholesterol, the lower the levels, the

> better it is for those with cardiovascular risk factors.

> .....

[Guest guest]

The International Network of Cholesterol Skeptics

http://www.thincs.org/

----- Original Message -----

From: " old542000 " <apater@...>

< >

Sent: Wednesday, July 14, 2004 8:17 AM

Subject: [ ] Re: New Cholesterol guidelines

Hi All,

Please see the pdf-available below.

Cheers, Al Pater.

[Guest guest]

Hi Bruce:

" In the Framingham study, there has never been a heart

attack in anyone with a total cholesterol under 155. "

Source: Jeff Novick, in post #13230 at .

Rodney.

> The International Network of Cholesterol Skeptics

> http://www.thincs.org/

[Guest guest]

>>> " In the Framingham study, there has never been a heart attack in

anyone with a total cholesterol under 155. "

>>Source: Jeff Novick, in post #13230 at .

That's actually a statement from Dr Castelli, who directed the

Framingham study for almost 50 years.