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RE: Who is Caloric Restriction?

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Perhaps this is an opportunity to better define or clarify the goals and

appropriate discussions for the sundry CR lists.

I am familiar with Dean Pomerleau and Rae. While I wouldn't

characterize either as moderate I'm not ready to label either as fanatical.

I consider both to be in honest pursuit of scientific knowledge and how it

relates to practice of CR.

I will leave it to Francesca to define where the " support " list fits in the

grand scheme of all things " CR " , but I agree it is probably not " the " forum

for rehashing technical questions that have been previously well explored on

the science list. While CR may be fresh and new to many, the classic

questions (like " how " ) have been explored for years. While I don't pretend

all (or any) of the answer are final, these issues have been long debated by

wiser than I.

JR

PS: for the record I hold Dean and in high regard. Both are more

rigorous than I in research before making posts and in general conservative

about offering advice. They have both advanced our understanding of CR

science greatly.

-----Original Message-----

From: Francesca Skelton [mailto:fskelton@...]

Sent: Sunday, August 01, 2004 8:26 AM

Subject: Re: [ ] What is Caloric Restriction?

My point is that that we don't all hold in such awe that we take

every word he speaks as gospel. As said recently (something

like): " If you think you know everything about CR or the human body,

you're just kidding yourself " : (or something like that).

Both Dean and are (or at least used to be) quite fanatical in their

CR agendas - by their own definitions. That alone is a turn off for me (and

probably a few others). But of course we won't know who's right for a long

time (unless some of us get sick or drop dead before that).

on 8/1/2004 6:07 AM, Dowling at dowlic@... wrote:

> True, Francesca, it would be more direct of me to directly quote the study

> or analysis thereof that led to 's statement, rather than quote

him.

> I do think, however, that much of what members of other CR organizations

> have offered regarding information pertinent to CR is rather relevant to

us

> all.

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I have an old e-mail in my archives which states that is 6 feet tall

and weighs 115 lbs (unless he's gained some weight since then). What would

it take to be fanatical? (A rhetorical question).

on 8/1/2004 10:59 AM, john roberts at johnhrob@... wrote:

> I am familiar with Dean Pomerleau and Rae. While I wouldn't

> characterize either as moderate I'm not ready to label either as fanatical.

> I consider both to be in honest pursuit of scientific knowledge and how it

> relates to practice of CR.

>

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Hi folks:

I guess it is nice to have people like that around. Makes me think

of the canaries in the coal mine.

Rodney.

>

>

> > I am familiar with Dean Pomerleau and Rae. While I

wouldn't

> > characterize either as moderate I'm not ready to label either as

fanatical.

> > I consider both to be in honest pursuit of scientific knowledge

and how it

> > relates to practice of CR.

> >

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I guess I was reacting to what seemed (to me) like a pejorative

characterization of an individual who wasn't even posting here. I guess we

could " all " be considered fanatical for actually considering eating " less "

food than normal.

I consider 115 @ 6' well below what I would personally be comfortable with,

but as long as he is healthy, and afaik his practice hasn't led to ER

visits, I respect his right to pursue his beliefs and perhaps in so doing

expand our knowledge of what the practical limits may be.

I consider like the strict mentor who doesn't suffer fools kindly

but is willing to share what he knows with those willing to present

thoughtful questions. I don't know or care what he weighs as long as he

lives longer than me and I can continue to benefit from his knowledge.

I very much appreciate the work you do here, I also see value in the other

list(s).

JR

FWIW I have actively lobbied at least one individual who does appear to be

hurting himself with his version of CR (without apparent success).

-----Original Message-----

From: Francesca Skelton [mailto:fskelton@...]

Sent: Sunday, August 01, 2004 8:00 PM

Subject: Re: [ ] Who is Caloric Restriction?

I have an old e-mail in my archives which states that is 6 feet tall

and weighs 115 lbs (unless he's gained some weight since then). What would

it take to be fanatical? (A rhetorical question).

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This email has been scanned by Internet Pathway's Email

Gateway scanning system for potentially harmful content,

such as viruses or spam. Nothing out of the ordinary was

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I have a son 6-2 175# - he's skinny - naturally.

Son-in-law 6-1 175# - he's skinny - naturally.

Another son 6' - always been 135# - skinny - naturally.

Another son got up to 225# - not skinny - not "fat" - presses 350#. Now 204# - still presses a lot. He's a big guy - not the biggest, but nobody messes with him (except women). That's important to some guys.

I was 234# fat, now a sure 175# as of this morning. Not skinny ( I used to be) - not fat - I can pick up MR AND Dean and I can carry Dean up the stairs easily (not bad for 68yo?). It's all about what you want your body to be.

I kinda like Micky who is proud of his physique, and does it on CR.

I heard a guy , this morning on CSP2 - Weiner, a Princeton scientist, talking about his book "His Brothers Keeper". He was emphatic about how complicated things get at the cellular level (that in 2004).

We're only scratching the surface on knowledge of the human body. No one can be a guru yet. And this health nut business has been going on to my recollection, since 1947 when Gaylord Houser first appeared on TV. He was instrumental in the demise of my aunt at 59yo, who thought he was an expert. Perhaps that's why I'm so critical of the "experts".

Regards.

----- Original Message -----

From: Francesca Skelton

Sent: Sunday, August 01, 2004 8:00 PM

Subject: Re: [ ] Who is Caloric Restriction?

I have an old e-mail in my archives which states that is 6 feet talland weighs 115 lbs (unless he's gained some weight since then). What wouldit take to be fanatical? (A rhetorical question).on 8/1/2004 10:59 AM, john roberts at johnhrob@... wrote:> I am familiar with Dean Pomerleau and Rae. While I wouldn't> characterize either as moderate I'm not ready to label either as fanatical.> I consider both to be in honest pursuit of scientific knowledge and how it> relates to practice of CR.>

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  • 2 months later...

Why would you be uncomfortable at this height/weight ratio if you knew

you were on right track with your CRON?

I ask becuase I don't know.

--- In , " john roberts " <johnhrob@n...>

wrote:

> I guess I was reacting to what seemed (to me) like a pejorative

> characterization of an individual who wasn't even posting here. I

guess we

> could " all " be considered fanatical for actually considering eating

" less "

> food than normal.

>

> I consider 115 @ 6' well below what I would personally be

comfortable with,

> but as long as he is healthy, and afaik his practice hasn't led to ER

> visits, I respect his right to pursue his beliefs and perhaps in so

doing

> expand our knowledge of what the practical limits may be.

>

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Hi Chris:

Because weighing 115 pounds at six foot tall will seem excessively

thin to many people, including me.

Rodney.

> > I guess I was reacting to what seemed (to me) like a pejorative

> > characterization of an individual who wasn't even posting here. I

> guess we

> > could " all " be considered fanatical for actually considering

eating

> " less "

> > food than normal.

> >

> > I consider 115 @ 6' well below what I would personally be

> comfortable with,

> > but as long as he is healthy, and afaik his practice hasn't led

to ER

> > visits, I respect his right to pursue his beliefs and perhaps in

so

> doing

> > expand our knowledge of what the practical limits may be.

> >

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Practicing CRAN if we are correct in our assumptions promises to slow aging.

The relationship appears to be pretty linear with more restriction resulting

in slower aging and longer " potential " lifespan. OTOH modest restriction

promises significant benefit in squaring the curve or not killing your self

fast.

About the only downside to modest restriction is that you can't eat

unlimited jelly donuts a non-issue since the vast majority of foods that

made me fat just aren't that appealing anymore. I enjoy eating well a few

times a year. When I do splurge I don't spend the calories I now value

highly on mediocre meals.

Regarding degree of restriction, while eating less and less calories can

drive the body into an even more hungry survival mode there are numerous

strategies to manage that. The real issue for me is philosophical or

perspective.

An interesting mental exercise is to ask yourself what would you do if you

knew you only had 1 day to live (hello jelly donuts). Than ask yourself the

same question for 1 week? 1 month? 1 year? There is not a right or wrong

answer to this exercise, but it should reveal things you really want to do

but have postponed for whatever reason. Now the kicker to this, is the fact

we may actually die tomorrow (me while jogging :-)... but guess what. I

can't think of a much better way to die that doesn't involve a pretty young

blond movie starlet.... oops sorry.

I am trying to hedge my bets. Live my life so if I do die tomorrow I have no

regrets, but not incur any physical debt today my body can't easily pay when

I don't die tomorrow. I recall my shock when I lived past 40. I now

appreciate that I could live twice that or more, but I am not skipping my

Thursday basketball game because of how my knees " may " feel at 100, or

allowing my weight/strength to drop so low I can no longer compensate for

competitors' size advantage while playing ball by knocking down the outside

shot or out-hustling the usually out of breath ad-libbers I match up with.

I'm a few weeks away from 56YO and I don't expect to compete against players

as young as HS forever, but I'm sure going to try.

I am aware of one CR'd individual who started out with my height (5'10 " ) and

has restricted himself down below 100 lbs. He has even lost a few inches of

height in the process. I see that as a clear example of where I could be if

I chose extreme CR. For right now I feel the cost of carrying some 50 more

pounds is well worth the price in the QOL I enjoy from them. Who knows how

I'll feel tomorrow, that's another day.

You must find your own path, as you will have different goals and sources of

pleasure.

JR

-----Original Message-----

From: chrisjohns2 [mailto:chrisjohns2@...]

Sent: Monday, October 18, 2004 5:38 PM

Subject: [ ] Re: Who is Caloric Restriction?

Why would you be uncomfortable at this height/weight ratio if you knew

you were on right track with your CRON?

I ask becuase I don't know.

--- In , " john roberts " <johnhrob@n...>

wrote:

> I guess I was reacting to what seemed (to me) like a pejorative

> characterization of an individual who wasn't even posting here. I

guess we

> could " all " be considered fanatical for actually considering eating

" less "

> food than normal.

>

> I consider 115 @ 6' well below what I would personally be

comfortable with,

> but as long as he is healthy, and afaik his practice hasn't led to ER

> visits, I respect his right to pursue his beliefs and perhaps in so

doing

> expand our knowledge of what the practical limits may be.

>

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I would say it doesn't just "seem" excessively thin. It may very well be. I calculate that to be a BMI of about 16.53. He may be a bit higher than that, but he is clearly under 17. Bone mass issues come into play before this level, don't they? Also, what about heart muscle mass? Seems a bit dangerous . . .

Rodney <perspect1111@...> wrote:

Hi Chris:Because weighing 115 pounds at six foot tall will seem excessively thin to many people, including me.Rodney.> > I guess I was reacting to what seemed (to me) like a pejorative> > characterization of an individual who wasn't even posting here. I> guess we> > could "all" be considered fanatical for actually considering eating> "less"> > food than normal.> > > > I consider 115 @ 6' well

below what I would personally be> comfortable with,> > but as long as he is healthy, and afaik his practice hasn't led to ER> > visits, I respect his right to pursue his beliefs and perhaps in so> doing> > expand our knowledge of what the practical limits may be.> >__________________________________________________

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Hi folks:

The mice that are put on 40% CR weigh about 50% less than those that

are fully fed, and live about 40% longer. Presumably this is not

translatable to humans. But if it were translatable, can many of us

imagine ourselves weighing 50% less than our set points? GULP!

So perhaps in comparison with the CR mice 115 pounds at 6 foot is not

much out of line. But I would want to see a few more canaries out

there before I would try a 50% weight reduction. In my case I would

have a BMI of 12.3! I seem to remember that that is the level

associated with death from starvation in famines.

Rodney.

> > > I guess I was reacting to what seemed (to me) like a pejorative

> > > characterization of an individual who wasn't even posting here.

I

> > guess we

> > > could " all " be considered fanatical for actually considering

> eating

> > " less "

> > > food than normal.

> > >

> > > I consider 115 @ 6' well below what I would personally be

> > comfortable with,

> > > but as long as he is healthy, and afaik his practice hasn't led

> to ER

> > > visits, I respect his right to pursue his beliefs and perhaps

in

> so

> > doing

> > > expand our knowledge of what the practical limits may be.

> > >

>

>

>

>

>

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Correction: I calculate the BMI to be 15.63, a bit under 16. That is quite thin indeed.

I know some people can't help it, even at very moderate calorie restriction, but I wouldn't want to get there myself.

Rodney <perspect1111@...> wrote:

Hi folks:The mice that are put on 40% CR weigh about 50% less than those that are fully fed, and live about 40% longer. Presumably this is not translatable to humans. But if it were translatable, can many of us imagine ourselves weighing 50% less than our set points? GULP!So perhaps in comparison with the CR mice 115 pounds at 6 foot is not much out of line. But I would want to see a few more canaries out there before I would try a 50% weight reduction. In my case I would have a BMI of 12.3! I seem to remember that that is the level associated with death from starvation in famines.Rodney.> > > I guess I was reacting

to what seemed (to me) like a pejorative> > > characterization of an individual who wasn't even posting here. I> > guess we> > > could "all" be considered fanatical for actually considering > eating> > "less"> > > food than normal.> > > > > > I consider 115 @ 6' well below what I would personally be> > comfortable with,> > > but as long as he is healthy, and afaik his practice hasn't led > to ER> > > visits, I respect his right to pursue his beliefs and perhaps in > so> > doing> > > expand our knowledge of what the practical limits may be.> > >> > > > >

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Another possible consideration is that animals CR'd from birth or before

will attain less stature and will have a smaller frame. In absolute caloric

terms the smaller critter may not be as restricted. A human CR'd from birth

may not grow to 6'. This is a complex issue with many considerations.

IMO the bottom line still remains QOL. What is the point of extending life

if we are not living it fully? Postponing present for future gratification

is a characteristic of higher level though, but I wouldn't forgo a vital

middle age for some hypothetical golden years. We should be able to have our

cake and not eat it too..

YMMV

JR

-----Original Message-----

From: Rodney [mailto:perspect1111@...]

Sent: Tuesday, October 19, 2004 3:16 PM

Subject: [ ] Re: Who is Caloric Restriction?

Hi folks:

The mice that are put on 40% CR weigh about 50% less than those that

are fully fed, and live about 40% longer. Presumably this is not

translatable to humans. But if it were translatable, can many of us

imagine ourselves weighing 50% less than our set points? GULP!

So perhaps in comparison with the CR mice 115 pounds at 6 foot is not

much out of line. But I would want to see a few more canaries out

there before I would try a 50% weight reduction. In my case I would

have a BMI of 12.3! I seem to remember that that is the level

associated with death from starvation in famines.

Rodney.

> I would say it doesn't just " seem " excessively thin. It may very

well be. I calculate that to be a BMI of about 16.53. He may be a bit

higher than that, but he is clearly under 17. Bone mass issues come

into play before this level, don't they? Also, what about heart

muscle mass? Seems a bit dangerous . . .

>

>

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In message 14018 (Aug 5, 2004), I asked the question " What is CRON? -

18% more food? " . The reason for the question was that the food

consumed on a weight basis is greater for CR animals than those fed ad

libitum. This is even reported on Masoro's classic paper " Action of

food restriction in delaying the aging process " Proc. Natl Acad. Sci.

Vol 79, pp.4239-4241, July 1982.

I think that food consumption must be adjusted according to the

stature at which CR is commenced. When CR is started in adolescence,

the body grows only to the level that the nutrition can sustain.

Thus, animals on a 40% restriction diet achive a size that is only 50%

of animals fed ad libitum. Once you have achieved full size you

cannot hope to survive on a 40% calorie restriction. Recent postings

indicated that around 14% was optimum.

If you are a 6-foot male and eat less than 2000 calories, you are more

likely to have nutritional deficiencies rather than a long life. The

minimum recommended for that height is around 2300 calories/day, but

you can calculate the requirements for your specific measurements

using the -Benedict equations and plug in the proper level of

activity. 2000 calories per day is about a 13% caloric restriction

(300/2300).

Tony

====

From: " " <crjohnr@b...>

Date: Tue Oct 19, 2004 4:46 pm

Subject: RE: [ ] Re: Who is Caloric Restriction?

Another possible consideration is that animals CR'd from birth or

before will attain less stature and will have a smaller frame. In

absolute caloric terms the smaller critter may not be as restricted. A

human CR'd from birth may not grow to 6'. This is a complex issue with

many considerations.

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I agree. We now have a file of previous posts (Extreme vs. Moderate CRON)

based on studies that an optimum BMI is between 18 and 22, and about a 15%

(only) reduction in Cal may be optimum (how fast we forget these previous

postings :-)). We also have some evidence that the human brain may not

function well on extreme CRON.

Of course time will tell. But between the evidence as discussed in the

aforementioned file, QOL issues, and my age, I'm sticking to moderation.

on 10/19/2004 6:25 PM, citpeks at citpeks@... wrote:

>

> In message 14018 (Aug 5, 2004), I asked the question " What is CRON? -

> 18% more food? " . The reason for the question was that the food

> consumed on a weight basis is greater for CR animals than those fed ad

> libitum. This is even reported on Masoro's classic paper " Action of

> food restriction in delaying the aging process " Proc. Natl Acad. Sci.

> Vol 79, pp.4239-4241, July 1982.

>

> I think that food consumption must be adjusted according to the

> stature at which CR is commenced. When CR is started in adolescence,

> the body grows only to the level that the nutrition can sustain.

> Thus, animals on a 40% restriction diet achive a size that is only 50%

> of animals fed ad libitum. Once you have achieved full size you

> cannot hope to survive on a 40% calorie restriction. Recent postings

> indicated that around 14% was optimum.

>

> If you are a 6-foot male and eat less than 2000 calories, you are more

> likely to have nutritional deficiencies rather than a long life. The

> minimum recommended for that height is around 2300 calories/day, but

> you can calculate the requirements for your specific measurements

> using the -Benedict equations and plug in the proper level of

> activity. 2000 calories per day is about a 13% caloric restriction

> (300/2300).

>

> Tony

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Hi Tony:

You raise an important distinction - between CR started at birth, or

instead at some later time. Do we know for sure that the 50% number

compares fully fed mice on the one hand, with those with CR onset at

birth? If the 50% lower body weight does indeed reflect those

differences then it doesn't have much relevance for us humans, since

few if any are going to choose to put their baby on CR immediately

following birth.

Do we know of studies where mice were restricted only after becoming

fully grown (the equivalent of, say, 22 years in human terms)? If

so, what happened to lifespan in that study at various degrees of

restriction? And what happened to body weight relative to set point?

Is this perhaps where the lifespan-shortened 'extreme CRON mice' data

come in?

While they didn't measure the weights of the fruit flies, it made no

difference to the *mortality rates* of the flies whatever age they

were put on 40% CR. For flies currently on CR mortality was 80% less

(sic) than for fully fed flies of the same age. Even if put on CR

very late in life, or if fully fed starting at age 60, after being on

CR from an early age.

Of course the same may not apply to mice. Nor humans.

Rodney.

>

> In message 14018 (Aug 5, 2004), I asked the question " What is

CRON? -

> 18% more food? " . The reason for the question was that the food

> consumed on a weight basis is greater for CR animals than those fed

ad

> libitum. This is even reported on Masoro's classic paper " Action of

> food restriction in delaying the aging process " Proc. Natl Acad.

Sci.

> Vol 79, pp.4239-4241, July 1982.

>

> I think that food consumption must be adjusted according to the

> stature at which CR is commenced. When CR is started in

adolescence,

> the body grows only to the level that the nutrition can sustain.

> Thus, animals on a 40% restriction diet achive a size that is only

50%

> of animals fed ad libitum. Once you have achieved full size you

> cannot hope to survive on a 40% calorie restriction. Recent

postings

> indicated that around 14% was optimum.

>

> If you are a 6-foot male and eat less than 2000 calories, you are

more

> likely to have nutritional deficiencies rather than a long life.

The

> minimum recommended for that height is around 2300 calories/day, but

> you can calculate the requirements for your specific measurements

> using the -Benedict equations and plug in the proper level of

> activity. 2000 calories per day is about a 13% caloric restriction

> (300/2300).

>

> Tony

>

> ====

> From: " " <crjohnr@b...>

> Date: Tue Oct 19, 2004 4:46 pm

> Subject: RE: [ ] Re: Who is Caloric Restriction?

>

> Another possible consideration is that animals CR'd from birth or

> before will attain less stature and will have a smaller frame. In

> absolute caloric terms the smaller critter may not be as

restricted. A

> human CR'd from birth may not grow to 6'. This is a complex issue

with

> many considerations.

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Hi All,

I beleve that CR initiated at earlier ages leads to reduced stature.

If we have much less height, 50% reduction in weight would not

translate into such a great affect on BMI.

Cheers, Al Pater.

--- In , " Rodney " <perspect1111@y...>

wrote:

>

> Hi folks:

>

> The mice that are put on 40% CR weigh about 50% less than those

that

> are fully fed, and live about 40% longer. Presumably this is not

> translatable to humans. But if it were translatable, can many of

us

> imagine ourselves weighing 50% less than our set points? GULP!

>

> So perhaps in comparison with the CR mice 115 pounds at 6 foot is

not

> much out of line. But I would want to see a few more canaries out

> there before I would try a 50% weight reduction. In my case I

would

> have a BMI of 12.3! I seem to remember that that is the level

> associated with death from starvation in famines.

>

> Rodney.

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--- In , " Rodney " <perspect1111@y...>

wrote:

> The mice that are put on 40% CR weigh about 50% less than those

that

> are fully fed, and live about 40% longer.

Do you know if those figures are for adult onset CR, or for CR

commenced immediately after weening?

Tim

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In a nutshell isn't adult onset CRON all about 'leaning down' to a few

%BF then sustaining that leanness over time with a nutrient dense

diet? Isn't this practicing CRON?

Just curious, Is anyone here under 5% BF??

> >

> > Hi folks:

> >

> > The mice that are put on 40% CR weigh about 50% less than those

> that

> > are fully fed, and live about 40% longer. Presumably this is not

> > translatable to humans. But if it were translatable, can many of

> us

> > imagine ourselves weighing 50% less than our set points? GULP!

> >

> > So perhaps in comparison with the CR mice 115 pounds at 6 foot is

> not

> > much out of line. But I would want to see a few more canaries out

> > there before I would try a 50% weight reduction. In my case I

> would

> > have a BMI of 12.3! I seem to remember that that is the level

> > associated with death from starvation in famines.

> >

> > Rodney.

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Hi Tim:

No I don't. That is the point I raise in my #15520.

Rodney.

>

> > The mice that are put on 40% CR weigh about 50% less than those

> that

> > are fully fed, and live about 40% longer.

>

> Do you know if those figures are for adult onset CR, or for CR

> commenced immediately after weening?

>

> Tim

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There are a number who measure <0% on tanita (not me).

Very low percentage BF is difficult to accurately measure.

I wouldn't try for the most CR'd award, which will be rewarded posthumously.

Eat good food. Eat less. Perhaps age slower and live longer, but always do

no harm.

JR

-----Original Message-----

From: chrisjohns2 [mailto:chrisjohns2@...]

Sent: Tuesday, October 19, 2004 7:51 PM

Subject: [ ] Re: Who is Caloric Restriction?

In a nutshell isn't adult onset CRON all about 'leaning down' to a few

%BF then sustaining that leanness over time with a nutrient dense

diet? Isn't this practicing CRON?

Just curious, Is anyone here under 5% BF??

-

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The 40% CR resulting in the 50% body weight is started after weaning

(on the 9th week for mice). Although I have read that mice started on

caloric restriction during adulthood can live longer, I don't recall

the degree of restriction that resulted in longevity and the resulting

body weights of the restricted mice compared to the controls.

With regard to percent of body fat, the American Council on Exercise

has these classifications:

.. . . . . . . . . . Women . . . . Men

Essential fat . . . 10-12% . . . 2-4%

Athletes . . . .. . 14-20% . . . 6-13%

I suppose that if you get below the essential fat you would have

to be dead, specially since the brain is over 50% fat. A 120 pound

man with a 2% body fat would have a total fat weight of 2.4 pounds.

The average human brain weighs about 1,300 to 1,400 grams

(http://faculty.washington.edu/chudler/facts.html). At 50% fat this

is 1300g*0.5/(454g/lb) = 1.43 lb of fat just in the brain. If the

total fat is only 2.4 in the whole body, and the brain has not been

compromised by reduction of fat, this leaves only one pound of fat for

the rest of the body (basically only the cell walls).

Myelin, the protective sheath that covers communicating neurons, is

composed of 30% protein and 70% fat. It does not seem wise to go

below 6% of body fat. If you do, you are going to lose some brain

mass.

Tony

>>>

From: " timwilliamrogers " <timwilliamrogers@y...>

Date: Tue Oct 19, 2004 8:28 pm

Subject: Re: Who is Caloric Restriction?

--- In , " Rodney " <perspect1111@y...>

wrote:

> The mice that are put on 40% CR weigh about 50% less than those

that are fully fed, and live about 40% longer.

Do you know if those figures are for adult onset CR, or for CR

commenced immediately after weaning?

>>>

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----- Original Message -----

From: Rodney

Sent: Tuesday, October 19, 2004 3:15 PM

Subject: [ ] Re: Who is Caloric Restriction?

Hi folks:The mice that are put on 40% CR weigh about 50% less than those that are fully fed, and live about 40% longer. Presumably this is not translatable to humans. But if it were translatable, can many of us imagine ourselves weighing 50% less than our set points? GULP!

If we started at birth we would be smaller and could eat less food comfortably. We have no idea how to translate the "set point" of the mice to humans.So perhaps in comparison with the CR mice 115 pounds at 6 foot is not much out of line. But I would want to see a few more canaries out there before I would try a 50% weight reduction. In my case I would have a BMI of 12.3! I seem to remember that that is the level associated with death from starvation in famines.Rodney.> I would say it doesn't just "seem" excessively thin. It may very well be. I calculate that to be a BMI of about 16.53. He may be a bit higher than that, but he is clearly under 17. Bone mass issues come into play before this level, don't they? Also, what about heart muscle mass? Seems a bit dangerous . . . > > >

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(Question) Francesca says 15%, others try 30% but how do you work

out the norm you are taking that percentage off.

I am five foot eleven and can keep a steady BMI of 18.5 on 1500

calories, so that is a 40% reduction on say 2500 cals (presuming

2500 is the norm for a male my height) which would seem okay, but

very low. But some studies that get trumpeted in popular press say

3000 calories is more the norm these days, in which case I would be

doing 50% CR and therefore that would be to low, so which is it ?.

When I try to work out my set point and then my target weight

via " beyond 120 year diet " I get 134 pounds which is roughly my

weight now.

...

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so you'd be about 28yo?

regards.

----- Original Message -----

From: rwalkerad1970

Sent: Wednesday, October 20, 2004 9:19 AM

Subject: [ ] Re: Who is Caloric Restriction?

(Question) Francesca says 15%, others try 30% but how do you work out the norm you are taking that percentage off.I am five foot eleven and can keep a steady BMI of 18.5 on 1500 calories, so that is a 40% reduction on say 2500 cals (presuming 2500 is the norm for a male my height) which would seem okay, but very low. But some studies that get trumpeted in popular press say 3000 calories is more the norm these days, in which case I would be doing 50% CR and therefore that would be to low, so which is it ?. When I try to work out my set point and then my target weight via "beyond 120 year diet" I get 134 pounds which is roughly my weight now. ...

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:

1) I'm not the one saying 15%. I'm saying read the files which have

studies in it that say so. Then do what you think best depending of which

studies you want to pay attention to.

I do suggest moderation for many reasons, one of which is that we just don't

really know what is optimum for humans. As says: " first do no

harm " . Some extremists have harmed their health.

When one of us reaches 115 years old or so, maybe we'll know more. Or

perhaps the opposite, when some of us drop dead from doing CR all wrong.

2) If you are a 5'11 " male and only weigh 134 pounds you must be quite thin.

I wouldn't lose any more weight if I were you. Especially if you are past

your youth.

3) Each must decide for themselves taking the various viewpoints into

account.

4) Bear in mind that if you get much thinner, you may start to " enjoy " the

side effects: feeling cold all the time, reduced or no libido,

osteoporosis, bony tush making it hard to sit, irritability, and others. I

personally don't feel that these side effects point to good health. But who

knows?

on 10/20/2004 10:19 AM, rwalkerad1970 at rwalkerad1970@... wrote:

>

> (Question) Francesca says 15%, others try 30% but how do you work

> out the norm you are taking that percentage off.

>

> I am five foot eleven and can keep a steady BMI of 18.5 on 1500

> calories, so that is a 40% reduction on say 2500 cals (presuming

> 2500 is the norm for a male my height) which would seem okay, but

> very low. But some studies that get trumpeted in popular press say

> 3000 calories is more the norm these days, in which case I would be

> doing 50% CR and therefore that would be to low, so which is it ?.

>

> When I try to work out my set point and then my target weight

> via " beyond 120 year diet " I get 134 pounds which is roughly my

> weight now.

>

> ...

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