Vitamin D and Breast Cancer

[Guest guest]

I am sorry to see what is happening also, frankly don't understand it,

thought we were all here to discuss things and perhaps challenge things too.

I have been buying Dale cod liver oil, supposed to be from

Norwegian sources. I always take it in the cold weather for vit D and A.

What does the Omega Plan book say about cod liver oil?

Annette

----- Original Message -----

From: PJ Macon <pjmacon@...>

It saddens me to see what's happening on the list. I've seen this

>happen on other lists...on various topics in the past

>

>

>Vitamin D is very inexpensive!! If you purchase the dry form without

>the added Vitamin A...the risk of overdose is reduced.

>

>Regards,

>Pamela

>

>Vitamin D adequacy: a possible relationship to

>breast cancer.

>

>

>,

>

>-

>

>Vitamin D and breast cancer.

>

>Christakos S

>

>Department of Biochemistry and Molecular Biology, University of

>Medicine and

>Dentistry of New Jersey, New Jersey Medical School, Newark, USA.

>

>1. 1,25-Dihydroxyvitamin D3, the biologically active form of vitamin

>D, in addition to

>regulating calcium homeostasis, also has antiproliferative and

>prodifferentiating

>effects.

>

>2. Most studies concerning the therapeutic potential of analogs of

>1,25(OH)2D3, which are antiproliferative and prodifferentiating but do

>not cause

>hypercalcemia, have been done using leukemic cells.

>

>3. Recent evidence from both in

>vivo and in vitro studies has indicated that 1,25(OH)2D3 or analogs of

>1,25(OH)2D3

>can inhibit the growth of breast cancer cells, thus suggesting the

>therapeutic

>potential of analogs of 1,25(OH)2D3 in the treatment of breast cancer.

>

>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

>http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7955119 & form=6 & db=m

& Dopt=b

>

>Carcinogenesis 1994 Nov;15(11):2645-8

>

>Mammary ductal epithelial cell hyperproliferation

>and hyperplasia induced by a nutritional stress diet

>containing four components of a western-style

>diet.

>

>Khan N, Yang K, Newmark H, Wong G, Telang N, Rivlin R, Lipkin M

>

>Memorial Sloan-Kettering Cancer Center, Irving Weinstein Laboratory,

>New York, NY.

>

>We have studied effects of several nutrients on the proliferation of

>mammary ductal

>epithelial cells in C57BL/6J virgin female mice, using morphometry and

>[3H]dT in vivo

>labeling.

>

>A nutritional stress diet was given based on the AIN-76A

>semi-synthetic diet

>modified to contain four significant risk factors of a Western-style

>diet: high fat and

>phosphate and decreased calcium and vitamin D. The numbers of large,

>intermediate

>and terminal ducts and proliferating epithelial cells in mammary

>glands were assayed

>in control and stress diet groups.

>

>An increased number of mammary ducts and

>increased number of proliferating cells were found at the level of the

>small terminal

>ducts, a cancer-prone region in the mammary gland in the stress diet

>group

>compared to the control group after 20 weeks of diet administration.

>Thus, mammary

>terminal ductal hyperproliferation, expansion in the size of the

>proliferative epithelial

>cell compartment and excessive duplication of mammary ductal

>epithelial cells were

>found after this Western-style diet containing decreased dietary

>calcium and vitamin

>D. These changes are similar to those developing in colonic epithelium

>of mice

>maintained on the same diets and during chemically induced colonic

>carcinogenesis.

>

>

>

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[Guest guest]

Hi folks:

http://news.bbc.co.uk/2/hi/health/3542344.stm

http://snipurl.com/8b1b

Rodney.