Re: Vitamin E Does NOT Protect against CVD

[Guest guest]

" Vitamin E " is a rather non-specific term. Vitamin E gamma (gamma

tocopherol) is the most abundant form found in the body due to ingestion of

food, while synthetic forms of alpha tocopherol are often given as

supplements. The supplemental form may cause displacement of the natural

gamma form, and thus cause imbalances in the body's homeostatic anti-oxidant

status.

It might be helpful to know what types of vitamin E are being referred to by

this study.

>From: " Rodney " <perspect1111@...>

>Reply-

>

>Subject: [ ] Vitamin E Does NOT Protect against CVD

>Date: Wed, 04 Aug 2004 22:39:38 -0000

>

>Hi folks:

>

>http://www.heartcenteronline.com/myheartdr/home/research-detail.cfm?

>reutersid=4562 & nl=4

>

>http://snipurl.com/88mx

>

>Rodney.

>

[Guest guest]

Hi :

Valid point. But this is a review of seven major studies. Do we

expect that they all got it wrong, by studying the wrong type of

vitamin E? Possibly. But I wouldn't bank on it. Probably the text

of the paper would tell ;; ^ )))

Rodney.

> " Vitamin E " is a rather non-specific term. Vitamin E gamma (gamma

> tocopherol) is the most abundant form found in the body due to

ingestion of

> food, while synthetic forms of alpha tocopherol are often given as

> supplements. The supplemental form may cause displacement of the

natural

> gamma form, and thus cause imbalances in the body's homeostatic

anti-oxidant

> status.

>

> It might be helpful to know what types of vitamin E are being

referred to by

> this study.

>

>

> >From: " Rodney " <perspect1111@y...>

> >Reply-

> >

> >Subject: [ ] Vitamin E Does NOT Protect against CVD

> >Date: Wed, 04 Aug 2004 22:39:38 -0000

> >

> >Hi folks:

> >

> >http://www.heartcenteronline.com/myheartdr/home/research-

detail.cfm?

> >reutersid=4562 & nl=4

> >

> >http://snipurl.com/88mx

> >

> >Rodney.

> >

[Guest guest]

Hi :

Just to clarify, I am not making a big issue about vitamin E. I

posted the reference to that study because it hopefully adds one more

piece that will eventually help complete the puzzle. (Very possibly

it is the piece you are suggesting. I.E. showing that alpha is not

the best way to go). I take 400 IU weekly (regular alpha) because I

thinks it very likely benefits in other ways. But I am more than

willing to change that (once the current jar is finished up!) if I

see persuasive information indicating that the form of the vitamin is

important.

Rodney.

> > > " Vitamin E " is a rather non-specific term. Vitamin E gamma

(gamma

> > > tocopherol) is the most abundant form found in the body due to

> >ingestion of

> > > food, while synthetic forms of alpha tocopherol are often given

as

> > > supplements. The supplemental form may cause displacement of the

> >natural

> > > gamma form, and thus cause imbalances in the body's homeostatic

> >anti-oxidant

> > > status.

> > >

> > > It might be helpful to know what types of vitamin E are being

> >referred to by

> > > this study.

> > >

> > >

> > > >From: " Rodney " <perspect1111@y...>

> > > >Reply-

> > > >

> > > >Subject: [ ] Vitamin E Does NOT Protect against

CVD

> > > >Date: Wed, 04 Aug 2004 22:39:38 -0000

> > > >

> > > >Hi folks:

> > > >

> > > >http://www.heartcenteronline.com/myheartdr/home/research-

> >detail.cfm?

> > > >reutersid=4562 & nl=4

> > > >

> > > >http://snipurl.com/88mx

> > > >

> > > >Rodney.

> > > >

> >

[Guest guest]

Hi All,

I was under the understanding that the alpha form is most abundant in

food.

Cheers, Al Pater.

> " Vitamin E " is a rather non-specific term. Vitamin E gamma (gamma

> tocopherol) is the most abundant form found in the body due to

ingestion of

> food, while synthetic forms of alpha tocopherol are often given as

> supplements. The supplemental form may cause displacement of the

natural

> gamma form, and thus cause imbalances in the body's homeostatic

anti-oxidant

> status.

>

> It might be helpful to know what types of vitamin E are being

referred to by

> this study.

>

>

> >From: " Rodney " <perspect1111@y...>

> >Reply-

> >

> >Subject: [ ] Vitamin E Does NOT Protect against CVD

> >Date: Wed, 04 Aug 2004 22:39:38 -0000

> >

> >Hi folks:

> >

> >http://www.heartcenteronline.com/myheartdr/home/research-

detail.cfm?

> >reutersid=4562 & nl=4

> >

> >http://snipurl.com/88mx

[Guest guest]

Hi All,

Eidelman RS, Hollar D, Hebert PR, Lamas GA, Hennekens CH.

Randomized trials of vitamin E in the treatment and prevention of

cardiovascular disease.

Arch Intern Med. 2004 Jul 26;164(14):1552-6.

PMID: 15277288 [PubMed - in process]

says only the alpha form was used.

Cheers, Al Pater.

> > " Vitamin E " is a rather non-specific term. Vitamin E gamma (gamma

> > tocopherol) is the most abundant form found in the body due to

> ingestion of

> > food, while synthetic forms of alpha tocopherol are often given

as

> > supplements. The supplemental form may cause displacement of the

> natural

> > gamma form, and thus cause imbalances in the body's homeostatic

> anti-oxidant

> > status.

> >

> > It might be helpful to know what types of vitamin E are being

> referred to by

> > this study.

> >

> >

> > >From: " Rodney " <perspect1111@y...>

> > >Reply-

> > >

> > >Subject: [ ] Vitamin E Does NOT Protect against CVD

> > >Date: Wed, 04 Aug 2004 22:39:38 -0000

> > >

> > >Hi folks:

> > >

> > >http://www.heartcenteronline.com/myheartdr/home/research-

> detail.cfm?

> > >reutersid=4562 & nl=4

> > >

> > >http://snipurl.com/88mx

> > >

> > >Rodney.

> > >

[Guest guest]

Hi All,

Shucks, just ask me for it.

Cheers, Al Pater.

> > > " Vitamin E " is a rather non-specific term. Vitamin E gamma

(gamma

> > > tocopherol) is the most abundant form found in the body due to

> >ingestion of

> > > food, while synthetic forms of alpha tocopherol are often given

as

> > > supplements. The supplemental form may cause displacement of the

> >natural

> > > gamma form, and thus cause imbalances in the body's homeostatic

> >anti-oxidant

> > > status.

> > >

> > > It might be helpful to know what types of vitamin E are being

> >referred to by

> > > this study.

> > >

> > >

> > > >From: " Rodney " <perspect1111@y...>

> > > >Reply-

> > > >

> > > >Subject: [ ] Vitamin E Does NOT Protect against

CVD

> > > >Date: Wed, 04 Aug 2004 22:39:38 -0000

> > > >

> > > >Hi folks:

> > > >

> > > >http://www.heartcenteronline.com/myheartdr/home/research-

> >detail.cfm?

> > > >reutersid=4562 & nl=4

> > > >

> > > >http://snipurl.com/88mx

> > > >

> > > >Rodney.

> > > >

> >

[Guest guest]

Hi All,

The alpha form in a huge study in a highly reputable journal found

the alpha form increased the risk of heart disease incidence or death

when supplemented. I recommend to get the balanced, somewhat more $,

mixed form of the vitamin E.

Cheers, Al.

> > > > " Vitamin E " is a rather non-specific term. Vitamin E gamma

> (gamma

> > > > tocopherol) is the most abundant form found in the body due to

> > >ingestion of

> > > > food, while synthetic forms of alpha tocopherol are often

given

> as

> > > > supplements. The supplemental form may cause displacement of

the

> > >natural

> > > > gamma form, and thus cause imbalances in the body's

homeostatic

> > >anti-oxidant

> > > > status.

> > > >

> > > > It might be helpful to know what types of vitamin E are being

> > >referred to by

> > > > this study.

> > > >

> > > >

> > > > >From: " Rodney " <perspect1111@y...>

> > > > >Reply-

> > > > >

> > > > >Subject: [ ] Vitamin E Does NOT Protect against

> CVD

> > > > >Date: Wed, 04 Aug 2004 22:39:38 -0000

> > > > >

> > > > >Hi folks:

> > > > >

> > > > >http://www.heartcenteronline.com/myheartdr/home/research-

> > >detail.cfm?

> > > > >reutersid=4562 & nl=4

> > > > >

> > > > >http://snipurl.com/88mx

> > > > >

> > > > >Rodney.

> > > > >

> > >

[Guest guest]

Hi All,

No, Rodney.

Cheers, Al Pater.

> Thanks, Al. Did it specify whether only the " natural " form of alpha

(d-alpha

> tocopherol) was used, or synthetic (dl-alpha-tocopherol)?

> > > > > >

> > > > >http://snipurl.com/88mx

[Guest guest]

Hi All,

I saw no mention of higher gamma form in food. Sure, on an equal

weight basis, the gamma form may perform some inportant functions

better.

Supplements are generally only in the alpha form.

Cheers, Al Pater.

>

Depends upon where one eats!

Ann Nutr Metab. 2004 Jul 12;48(3):169-188. Related Articles, Links

Gamma-Tocopherol - An Underestimated Vitamin?

Wagner KH, Kamal-Eldin A, Elmadfa I.

The main research activities of the last decades on tocopherols were

mainly

focused on alpha-tocopherol, in particular when considering the

biological

activities. However, recent studies have increased the knowledge on

gamma-tocopherol, which is the major form of vitamin E in the diet in

the

USA, but not in Europe. gamma-Tocopherol provides different

antioxidant

activities in food and in-vitro studies and showed higher activity in

trapping lipophilic electrophiles and reactive nitrogen and oxygen

species.

The lower plasma levels of gamma- compared to alpha-tocopherol might

be

discussed in the light of different bioavailability, but also in a

potential

transformation from gamma- into alpha-tocopherol. From the metabolism

end

product, only that of gamma-tocopherol

(2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman), but not

that of

alpha-tocopherol, was identified to provide natriuretic activity.

Studies

also indicate that only the gamma-tocopherol plasma level served as

biomarker for cancer and cardiovascular risk. Therefore, this paper

provides

a comprehensive review on gamma-tocopherol with emphasis on its

chemistry,

biosynthesis, occurrence in food, different intake linking to

different

plasma levels in USA and Europe, absorption and metabolism,

biological

activities, and possible role in human health. Copyright 2004 S.

Karger AG,

Basel

PMID: 15256801 [PubMed - as supplied by publisher]

>From: " old542000 "

>Reply-

>

>Subject: [ ] Re: Vitamin E Does NOT Protect against CVD

>Date: Thu, 05 Aug 2004 16:30:05 -0000

>

>Hi All,

>

>I was under the understanding that the alpha form is most abundant

in

>food.

>

>Cheers, Al Pater.

[Guest guest]

> > " Vitamin E " is a rather non-specific term. Vitamin E gamma (gamma

> > tocopherol) is the most abundant form found in the body due to

> ingestion of

> > food, while synthetic forms of alpha tocopherol are often given

as

> > supplements. The supplemental form may cause displacement of the

> natural

> > gamma form, and thus cause imbalances in the body's homeostatic

> anti-oxidant

> > status.

> >

> > It might be helpful to know what types of vitamin E are being

> referred to by

> > this study.

> >

> >

> > >From: " Rodney " <perspect1111@y...>

> > >Reply-

> > >

> > >Subject: [ ] Vitamin E Does NOT Protect against CVD

> > >Date: Wed, 04 Aug 2004 22:39:38 -0000

> > >

> > >Hi folks:

> > >

> > >http://www.heartcenteronline.com/myheartdr/home/research-

> detail.cfm?

> > >reutersid=4562 & nl=4

> > >

> > >http://snipurl.com/88mx

[Guest guest]

Hi All,

That was not the case in Israel or Europe. So, it depends. CRers

are hardly typical in their diets. I wonder.

Cheers, Al Pater.

> > Hi All,

> >

> > I was under the understanding that the alpha form is most

abundant

> in

> > food.

> >

> > Cheers, Al Pater.

>

> No. See:

>

> http://www.ajcn.org/cgi/content/full/74/6/714

[Guest guest]

I'm aware of only eight forms of vitamin E: alpha, beta, delta, and

gamma forms of tocopherol and of tocotrienol. What are the other 192

forms that you speak of?

> More junk science and junk meta-analysis then. There's over TWO

> HUNDRED different forms of Vitamin E in whole food. Who knows how

> many more remain yet to be identified?

>

> Logan

>

> --- In , " old542000 " <apater@m...>

> > says only the alpha form was used.

[Guest guest]

Here is More fog about Omega-3s, Pufa, Soy Isoflavones, Lycopene. Perhaps

this study is already been surpassed by more recent information, but here it

is, for whatever value it may have in clarifying this confusing area

Cohen LA.

American Health Foundation, Valhalla, New York 10595, USA. Lcohen@...

Nutrition and prostate cancer: a review.

Ann N Y Acad Sci 2002 Jun;963:148-55

Despite intense efforts, little is known about the etiology of prostate

cancer, and treatment of advanced forms of the disease has had limited

success. Nonetheless, epidemiologic studies combined with animal model and

in vitro experiments indicate that natural components of the diet, including

n-3 PUFA, the carotenoid lycopene, and the trace element selenium, may serve

as chemopreventive agents that suppress the growth and dissemination of

neoplastic prostate cells. Until further study, however, soy isoflavones

should be viewed with some caution, especially as adjuvant's to

chemotherapy, in patients with hormone-refractory prostate cancer. Future

studies, using different forms and doses of selenium and tomato carotenoids,

may shed new light on the etiology and prevention of prostate cancer.

Mike

-----Original Message-----

From: Rodney [mailto:perspect1111@...]

Sent: Wednesday, August 04, 2004 5:40 PM

Subject: [ ] Vitamin E Does NOT Protect against CVD

Hi folks:

http://www.heartcenteronline.com/myheartdr/home/research-detail.cfm?

reutersid=4562 & nl=4

http://snipurl.com/88mx

Rodney.

[Guest guest]

I don't think they've been formally named or even isolated yet.

Logan

> I'm aware of only eight forms of vitamin E: alpha, beta, delta, and

> gamma forms of tocopherol and of tocotrienol. What are the other

192

> forms that you speak of?